Výsledky vyhledávání - "Feng-Guang Rong"

Boron-Containing Heterocycles: Syntheses, Structures, and Properties of Benzoborauracils and a Benzoborauracil Nucleoside

Autor: Sheldon G. Shore, Glenn T. Jordan, Jin-Cong Zhuo, Feng-Guang Rong, Weihua Ji, Beverly A. Barnum, John C. Beeson, and Jianping Liu, Albert H. Soloway, Werner Tjarks

Publikováno v: The Journal of Organic Chemistry. 64:9566-9574

Benzo-fused boron-containing heterocycles (benzoborauracils), 1-hydroxy-1H-2,4,1-benzodiazaborin-3-one (3a), 1-hydroxy-2-methyl-1H-2,4,1-benzodiazaborin-3-one (3b), and 1-hydroxy-2-phenyl-1H-2,4,1-benzodiazaborin-3-one (3c) were synthesized, and thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9d2a4d022bf4be8064c930c7d2dd2e8
https://doi.org/10.1021/jo991176q

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Identification, development, synthesis and evaluation of boron-containing nucleosides for neutron capture therapy

Autor: A. K. M. Anisuzzaman, A. J. Lunato, Feng-Guang Rong, Albert H. Soloway, Beverly A. Barnum, David H. Ives, C. D. Barth, Jin-Cong Zhuo, Rolf F. Barth

Publikováno v: Journal of Organometallic Chemistry. 581:150-155

The development of boron compounds with the capacity for selectively targeting tumor cells would offer the potential for specifically destroying such cells using the capture reaction of the nonradioactive 10 B nuclide and thermal neutrons. The key pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9872c0f0b6168aea93946c14721cf84
https://doi.org/10.1016/s0022-328x(99)00085-6

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Synthesis and Biochemical Activity of Hydrophilic Carborane-Containing Pyrimidine Nucleosides as Potential Agents for DNA Incorporation and BNCT

Autor: Feng-Guang Rong, David H. Ives, Seiichiro Ikeda, Albert H. Soloway

Publikováno v: Nucleosides and Nucleotides. 16:379-401

A novel type of hydrophilic 5-tethered carborane-containing 2′-deoxyuridine derivative, SUB-7-DIOL, has been developed. This compound is a potential agent for DNA incorporation and BNCT, because it showed satisfactory aqueous solubility and demonst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f2e73fd20107e16d7eca3d2d5fc1945
https://doi.org/10.1080/07328319708001357

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Synthesis and Biochemical Activity of 5-Tethered Carborane-Containing Pyrimidine Nucleosides as Potential Agents for DNA Incorporation

Autor: Feng-Guang Rong, Albert H. Soloway, David H. Ives, Seiichiro Ikeda

Publikováno v: Nucleosides and Nucleotides. 14:1873-1887

Synthesis and biochemical evaluation of a series of 5-tethered carborane-containing pyrimidine nucleosides have been undertaken. The biochemical studies with human TK demonstrated that these compounds can be phosphorylated to the corresponding 5′-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::622b3697a5e2b8bf347278a90dbc4f8e
https://doi.org/10.1080/15257779508010710

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Synthesis of 5-Tethered Carborane-Containing Pyrimidine Nucleosides as Potential Agents for DNA Incorporation

Autor: Albert H. Soloway, Feng-Guang Rong

Publikováno v: Nucleosides and Nucleotides. 13:2021-2034

Several 5-substituted-2′-deoxyuridines have been prepared in which the carborane moiety is attached at the terminus of a flexible hydrocarbon chain containing an ester linkage. These boron moieties as the B-10 enriched compounds have potentiality f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e8de0a2a3cca7c0ad044e47d04d0cdf
https://doi.org/10.1080/15257779408010680

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Strategies for the design and synthesis of boronated nucleic acid and protein components as potential delivery agents for neutron capture therapy

Autor: Iwona M. Wyzlic, Albert H. Soloway, A. K. M. Anisuzzaman, Werner Tjarks, Feng-Guang Rong, Rolf F. Barth

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 28:1203-1213

Purpose : Strategies for the design and synthesis of boronated nucleosides, amino acids, and peptides as potential delivery agents for boron neutron capture therapy (BNCT) are described. Methods and Materials : For BNCT to be a useful treatment modal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d2c725b7f07f15f53d8ef0e59ec674
https://doi.org/10.1016/0360-3016(94)90495-2

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