Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Feng-Di T. Lung"'
Publikováno v:
Journal of Chemistry, Vol 2024 (2024)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by reduced dopamine levels in the brain, affecting over 6 million people worldwide. While current treatments for patients primarily focus on symptom relief, there is a necessity
Externí odkaz:
https://doaj.org/article/a30aeb799c97419198163bc133e8e04d
Publikováno v:
Journal of Peptide Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b37c969eec31bc48020b4cb1d153fd6
https://doi.org/10.1002/psc.3510
https://doi.org/10.1002/psc.3510
Publikováno v:
International Journal of Peptide Research and Therapeutics. 20:117-125
Osteoporosis is one of the major bone-related diseases. Among the biomarkers of bone resorption, type I collagen cross-linked N-telopeptides (NTx) are terminal metabolites specifically derived from the degradation of bone collagen, thus, the level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb5f30e8c80161cd03d692f6e3a4a176
https://doi.org/10.1007/s10989-013-9373-9
https://doi.org/10.1007/s10989-013-9373-9
Publikováno v:
Journal of Peptide Science. 19:676-683
Id proteins, inhibitors of DNA binding proteins, have highly conserved dimerization motif known as the helix-loop-helix (HLH) domain that acts as a negative regulator of basic HLH (bHLH) transcription factors. In signaling pathways, Id proteins play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0cc8df1f65a3de85cd4ed87cece6ed
https://doi.org/10.1002/psc.2549
https://doi.org/10.1002/psc.2549
Autor:
Yu-Cheng Hsiao, Wei-Ting Chao, Shu-Huai Tsai, Feng-Di T. Lung, Kee-Ching G. Jeng, Chen-Yu Lee, Yi-Jhen Lin
Publikováno v:
Medicinal Chemistry Research. 22:5337-5343
The growth factor receptor-bound protein-Src homology 2 (Grb2-SH2) domain plays an important role in the oncogenic Ras signaling pathway, which is involved in cell proliferation and differentiation. We focused on developing peptidic antagonists of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08547718ba4e829255d8a5f31004f39
https://doi.org/10.1007/s00044-013-0538-z
https://doi.org/10.1007/s00044-013-0538-z
Autor:
Zih-Jie Liao, Feng-Di T. Lung, Yu-Shan Wu, Chien-Chung Liou, Sheng-Kai Hsu, Fei-Yi Song, Kai-Shiuan Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:4185-4188
Antimicrobial peptides (AMPs) represent the first defense line against infection when organisms are infected by pathogens. These peptides are generally good targets for the development of antimicrobial agents. Peptide amide analogs of Ixosin-B, an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df906001ade3b925343316d62234cf39
https://doi.org/10.1016/j.bmcl.2012.04.018
https://doi.org/10.1016/j.bmcl.2012.04.018
Autor:
Feng-Di T. Lung, Shih-Ying Yang, Sheng-Chu Kuo, Yeh Chen, De-Len Yang, Chia-Xin Yang, Li-Jiau Huang
Publikováno v:
Journal of Peptide Science. 17:667-674
Id1 proteins, inhibitors of differentiation or DNA binding, act as dominant negative antagonists of the bHLH family of transcription factors, which play an important role in cellular development, proliferation, and differentiation. The mechanism of I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5483272b113c214e54eef1372bb01402
https://doi.org/10.1002/psc.1386
https://doi.org/10.1002/psc.1386
Publikováno v:
Protein & Peptide Letters. 15:806-810
The growth factor receptor-binding protein 2 – Src homology 2 (Grb2 – SH2) domain plays an important role in the oncogenic Ras signal transduction pathway, therefore, peptidic inhibitors of the Grb2 – SH2 domain has been chosen as our target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e6fa982830014a8a35f1c6a01b9924
https://doi.org/10.2174/092986608785203683
https://doi.org/10.2174/092986608785203683
Autor:
Bih-Show Lou, Peng Li, Marc C. Nicklaus, Feng-Di T. Lung, Megan L. Peach, Meng-Chin Chong, Chiung-Wen Chang, Peter P. Roller, Chien-Chung Liou
Publikováno v:
Biopolymers. 80:628-635
The growth factor receptor-binding protein-Src homology 2 (Grb2-SH2) domain plays an important role in the oncogenic Ras signal transduction pathway, which involves cell proliferation and differentiation. Therefore, the Grb2-SH2 domain has been chose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af571232fbc8ac9bba45715e4b2684b7
https://doi.org/10.1002/bip.20209
https://doi.org/10.1002/bip.20209
Autor:
Jya-Yin Tsai, Feng-Di T. Lung
Publikováno v:
Biopolymers. 71:132-140
The growth factor receptor-bound protein 2 (Grb2) plays an important role in the Ras signaling pathway. Several proteins were found to be overexpressed by oncogenes in the Ras signaling pathway, rendering Grb2 a potential target for the design of ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d29836f8dae3e2747e77b4a91a3d67
https://doi.org/10.1002/bip.10396
https://doi.org/10.1002/bip.10396