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SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest.

Autor: Wang C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Wang T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Department of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, 510900, China., Li KJ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Hu LH; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Li Y; Laboratory Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China., Yu YZ; Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510500, China., Xie T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Zhu S; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China., Fu DJ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Wang Y; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China., Zeng XZ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Liu FP; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China., Chen H; Luoyang Key Laboratory of Organic Functional Molecules, College of Food and Drug, Luoyang Normal University, Luoyang, Henan, 471934, China., Chen ZS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA., Feng NH; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China. Electronic address: fnh888@njmu.edu.cn., Liu J; Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: liujhua@smu.edu.cn., Jiang Y; Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: jiang48231@163.com., Zhao SC; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510500, China. Electronic address: lulululu@smu.edu.cn.

Publikováno v: Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216464. Date of Electronic Publication: 2023 Oct 24.