Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Feng Lai Yuan"'
Autor:
Qian-Yuan Wu, Xia Li, Zong-Ning Miao, Jun-Xing Ye, Bei Wang, Feng Zhang, Rui-Sheng Xu, Dong-Lin Jiang, Ming-Dong Zhao, Feng Lai Yuan
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Osteoporosis is a metabolic bone disease characterized by a decrease in bone mass and degradation of the bone microstructure, which increases bone fragility and fracture risk. However, the molecular mechanisms of osteoporosis remain unclear. Long non
Externí odkaz:
https://doaj.org/article/5cd54f397fa74a4ead92b480e4e62b47
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Rheumatoid arthritis is an autoimmune disease characterized by synovial hyperplasia and progressive joint destruction. As reported previously, recombinant human endostatin (rhEndostatin) is associated with inhibition of joint bone destruction present
Externí odkaz:
https://doaj.org/article/13bbbd7ca0b449f19efd9ec57588a288
Autor:
Tian‐Hao Liu, Chen‐Yang Zhang, Hang Zhang, Jing Jin, Xue Li, Shi‐Qiang Liang, Yu‐Zheng Xue, Feng‐Lai Yuan, Ya‐Hong Zhou, Xiu‐Wu Bian, Hong Wei
Publikováno v:
iMeta, Vol 3, Iss 3, Pp n/a-n/a (2024)
Abstract The drug response phenotype is determined by a combination of genetic and environmental factors. The high clinical conversion failure rate of gene‐targeted drugs might be attributed to the lack of emphasis on environmental factors and the
Externí odkaz:
https://doaj.org/article/62da27fcbce3441ab799f5abade67645
Autor:
Zhenyu Zhang, Minnan Chen, Wenjing Zhan, Yuechun Chen, Tongtong Wang, Zhonghua Chen, Yifei Fu, Gang Zhao, Dong Mao, Jingjing Ruan, Feng-Lai Yuan
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Acid-sensing ion channel 1a (ASIC1a), a prominent member of the acid-sensing ion channel (ASIC) superfamily activated by extracellular protons, is ubiquitously expressed throughout the human body, including the nervous system and peripheral
Externí odkaz:
https://doaj.org/article/17241a19dd864c518a9a0150f53f246f
Autor:
Dan-yang Guo, Zhong-hua Chen, Yi-fei Fu, Yue-yue Li, Meng-nan Chen, Jun-jie Wu, Zheng-dong Yuan, Jun-Xing Ye, Xia Li, Feng-lai Yuan
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e22629- (2024)
Externí odkaz:
https://doaj.org/article/9d2d3110ec3d40fb8e2b28e4237c4000
Autor:
Zhong-Hua Chen, De-Yan Du, Yi-Fei Fu, Jun-Jie Wu, Dan-Yang Guo, Yue-Yue Li, Meng-Nan Chen, Zheng-Dong Yuan, Kai-Wen Zhang, Zhen-Yu Zhang, Xia Li, Feng-Lai Yuan
Publikováno v:
Materials Today Bio, Vol 22, Iss , Pp 100747- (2023)
Bone targeted delivery of estrogen offers great promise for the clinical application of estrogen in the treatment of postmenopausal osteoporosis (PMOP). However, the current bone-targeted drug delivery system still has several issues that need to be
Externí odkaz:
https://doaj.org/article/920af887a1dc4aaa8803f480b8a6b734
Autor:
Dan-yang Guo, Zhong-hua Chen, Yi-fei Fu, Yue-yue Li, Meng-nan Chen, Jun-jie Wu, Zheng-dong Yuan, Jun-Xing Ye, Xia Li, Feng-lai Yuan
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17841- (2023)
The remodeling of actin cytoskeleton of osteoclasts on the bone matrix is essential for osteoclastic resorption activity. A specific regulator of the osteoclast cytoskeleton, integrin αvβ3, is known to provide a key role in the degradation of miner
Externí odkaz:
https://doaj.org/article/40cf2110105f4c2cb463a05c75c04bd2
Autor:
Ke-wei Wang, Mei-dan Wang, Zi-xi Li, Ben-shun Hu, Jian-feng Huang, Jun-jie Wu, Zheng-dong Yuan, Xiao-long Wu, Qin-fang Yuan, Yi-fan Sun, Feng-lai Yuan
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13831- (2023)
Cuprotosis is a new programmed cell death related to cancer. However, the characteristics of cuprotosis in gastric cancer (GC) remain unknown. Ten cuprotosis molecules from 1544 GC patients were used to identify three GC molecular genotypes. Cluster
Externí odkaz:
https://doaj.org/article/30daa71fde544ef9818514c7fae29d1e
Autor:
Yi Qin, Zhong-hua Chen, Jun-Jie Wu, Zhen-Yu Zhang, Zheng-Dong Yuan, Dan-Yang Guo, Meng-Nan Chen, Xia Li, Feng-Lai Yuan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114019- (2023)
The circadian clock regulates many key physiological processes such as the sleep–wake cycle, hormone release, cardiovascular health, glucose metabolism and body temperature. Recent evidence has suggested a critical role of the circadian system in c
Externí odkaz:
https://doaj.org/article/9ebde8020c8f4ce59a7f8043e4750d4b
Autor:
Ke-wei Wang, Mei-dan Wang, Zi-xi Li, Ben-shun Hu, Jun-jie Wu, Zheng-dong Yuan, Xiao-long Wu, Qin-fang Yuan, Feng-lai Yuan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveThe aim of the study was to propose a signature based on genes associated with antigen processing and presentation (APscore) to predict prognosis and response to immune checkpoint inhibitors (ICIs) in advanced gastric cancer (aGC).Background
Externí odkaz:
https://doaj.org/article/f37e3df173364d809e22fc82cc9d8efc