Výsledky vyhledávání - "Feng Chang Yen"

Relapse and Long-Acting Injectable Risperidone: A 1-Year Mirror Image Study with a National Claims Database in Taiwan

Autor: Kuan-Pin Su, Hui Chih Chang, Chao Hsiun Tang, Feng Chang Yen, Shih-Jen Tsai

Publikováno v: Value in Health. 12:S118-S121

Objectives: The development of long-acting, injectable atypical antipsychotics has provided a new paradigm for schizophrenia treatment. The study was designed to assess whether a risperidone long-acting injection (RLAI) is associated with reduced rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff61e7c5f36ec5746f2963719351c93c
https://doi.org/10.1111/j.1524-4733.2009.00643.x

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Haplotype analysis of single nucleotide polymorphisms in the vascular endothelial growth factor (VEGFA) gene and antidepressant treatment response in major depressive disorder

Autor: Tai-Jui Chen, Shih-Jen Tsai, Chen-Jee Hong, Ying-Jay Liou, Feng-Chang Yen, Younger W.-Y. Yu, Mao-Liang Chen, Sheue-Jane Hou

Publikováno v: Psychiatry Research. 169:113-117

Vascular endothelial growth factor (VEGF) has been implicated in neurotrophy and neurogenesis, which play a pivotal role in brain development and may be involved in antidepressant therapeutic mechanisms. Recent animal studies demonstrate that VEGF le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02aa810a49d9ed594e23f23e111cf00f
https://doi.org/10.1016/j.psychres.2008.06.028

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X-box binding protein 1 (XBP1) C−116G polymorphisms in bipolar disorders and age of onset

Autor: Shih-Jen Tsai, Sheue-Jane Hou, Chen-Jee Hong, Chih-Ya Cheng, Feng-Chang Yen

Publikováno v: Neuroscience Letters. 367:232-234

X-box binding protein 1(XBP1), a critical gene in the endoplasmic reticulum stress response, is located on chromosome 22q12, which has been linked with bipolar disorders in several studies. Recently, associations have been reported between a polymorp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc46d714962fd3f543719dbb79dcceaf
https://doi.org/10.1016/j.neulet.2004.06.012

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Polymorphisms in LMNA and near a SERPINA13 gene are not associated with cognitive performance in Chinese elderly males without dementia

Autor: Ying Jay Liou, Heng Liang Yeh, Feng Chang Yen, Shih-Jen Tsai, Mu En Liu, Chen-Jee Hong, Sheue Jane Hou, Albert C. Yang

Publikováno v: Neuroscience letters. 504(1)

Aging is associated with cognitive deterioration. A recent study showed two polymorphisms (rs505058 in LMNA and rs11622883 near a SERPINA13 gene), identified in a genome-wide association study of late-onset Alzheimer's disease, to be associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f635f84419b04957032bc383a2204f3
https://pubmed.ncbi.nlm.nih.gov/21903150

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TGF-β1 blockade of microglial chemotaxis toward Aβ aggregates involves SMAD signaling and down-regulation of CCL5

Autor: Young Ji Shiao, Huey Jen Tsay, Chih Ming Pan, Fong Lee Huang, Wei Chao Huang, Yen-Jen Sung, Feng Chang Yen, Feng Shiun Shie, Cheng Ning Yang

Publikováno v: Journal of Neuroinflammation, Vol 7, Iss 1, p 28 (2010)
Journal of Neuroinflammation

BackgroundOveractivated microglia that cluster at neuritic plaques constantly release neurotoxins, which actively contribute to progressive neurodegeneration in Alzheimer's disease (AD). Therefore, attenuating microglial clustering can reduce focal n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaa6f9fb8345734f7fb1901fe457d0f
http://www.jneuroinflammation.com/content/7/1/28

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Enlargement of Abeta aggregates through chemokine-dependent microglial clustering

Autor: Wei Chao Huang, Young Ji Shiao, Feng Chang Yen, Cheng Ning Yang, Huey Jen Tsay, Feng Shiun Shie, Fong Lee Huang, Yen-Jen Sung, Jin Lieh Chan

Publikováno v: Neuroscience research. 63(4)

The number of microglia surrounding senile plaques is correlated with the size of plaques in Alzheimer's disease (AD). It is unclear whether more microglia are passively recruited toward larger senile plaques or, conversely, microglia recruited to se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b390a8beabd00d621486dd253e638d9b
https://pubmed.ncbi.nlm.nih.gov/19367788

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Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant treatment response

Autor: Chen-Jee Hong, Sheue-Jane Hou, Tai-Jui Chen, Younger W.-Y. Yu, Ying-Jay Liou, Shih-Jen Tsai, Feng-Chang Yen

Publikováno v: Progress in neuro-psychopharmacologybiological psychiatry. 33(4)

Tryptophan hydroxylase-2 (TPH2) is the rate-limiting biosynthetic isoenzyme for serotonin that is preferentially expressed in the brain and has been implicated in the pathogenesis of major depressive disorder (MDD) and in the mechanism of antidepress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9598053b4f87c4e772f586e3ec36ac9a
https://pubmed.ncbi.nlm.nih.gov/19272410

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Is dysfunction of the tissue plasminogen activator (tPA)-plasmin pathway a link between major depression and cardiovascular disease?

Autor: Feng-Chang Yen, Shih-Jen Tsai, Sheue-Jane Hou

Publikováno v: Medical hypotheses. 72(2)

Epidemiological, genetic and clinical studies have demonstrated an association between major depressive disorder (MDD) and cardiovascular disease (CVD). For example, MDD is a risk factor for the development of CVD, while around one fifth of patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcde41be3cecde4f4701498c82a8826
https://pubmed.ncbi.nlm.nih.gov/18929445

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