Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Fenfei Leng"'
Autor:
Gabriela Hernández-Martínez, Miguel A. Ares, Roberto Rosales-Reyes, Jorge Soria-Bustos, Jorge Antonio Yañez-Santos, María L. Cedillo, Jorge A. Girón, Ygnacio Martínez-Laguna, Fenfei Leng, J. Antonio Ibarra, Miguel A. De la Cruz
Publikováno v:
mSphere, Vol 9, Iss 5 (2024)
ABSTRACT Enterobacter cloacae is an emerging pathogen isolated in healthcare-associated infections. A major virulence factor of this bacterium is the type VI secretion system (T6SS). The genome of E. cloacae harbors two T6SS gene clusters (T6SS-1 and
Externí odkaz:
https://doaj.org/article/677848c9969443dfbb7684f48f9008b9
Autor:
Zifang Deng, Fenfei Leng
Publikováno v:
ACS Omega, Vol 6, Iss 18, Pp 12205-12212 (2021)
Externí odkaz:
https://doaj.org/article/61fe109254424e43bfd75503a7b7689e
Autor:
Yunke Wang, Samantha Rakela, Jeremy W. Chambers, Zi-Chun Hua, Mark T. Muller, John L. Nitiss, Yuk-Ching Tse-Dinh, Fenfei Leng
Publikováno v:
ACS Omega, Vol 4, Iss 19, Pp 18413-18422 (2019)
Externí odkaz:
https://doaj.org/article/160a7ee6f656476ca20d7340cea6570e
Autor:
Kevin Jeanne Dit Fouque, Alyssa Garabedian, Fenfei Leng, Yuk-Ching Tse-Dinh, Francisco Fernandez-Lima
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 3619-3626 (2019)
Externí odkaz:
https://doaj.org/article/4e8f38d8c1e44760b5d954fe73f1e74f
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 74, Iss 3, Pp 400-405 (2018)
Crystal structure determination of doxorubicin nitrate, (DoxH)NO3, systematic name (7S,9S)-7-{[(2R,4S,5S,6S)-4-azaniumyl-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracen-5,12-dione nitrate, sho
Externí odkaz:
https://doaj.org/article/49d20c18df7447b286b31c59c09563d9
Autor:
Pamela K Garcia, Thirunavukkarasu Annamalai, Wenjie Wang, Raven S Bell, Duc Le, Paula Martin Pancorbo, Sabah Sikandar, Ahmed Seddek, Xufen Yu, Dianqing Sun, Anne-Catrin Uhlemann, Purushottam B Tiwari, Fenfei Leng, Yuk-Ching Tse-Dinh
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0207733 (2019)
We have previously reported the inhibition of bacterial topoisomerase I activity by a fluoroquinophenoxazine compound (FP-11g) with a 6-bipiperidinyl lipophilic side chain that exhibited promising antituberculosis activity (MIC = 2.5 μM against Myco
Externí odkaz:
https://doaj.org/article/d9bfda57d9f048fe980faa0d20768f76
Autor:
Lorraine Frost, Maria A M Baez, Christopher Harrilal, Alyssa Garabedian, Francisco Fernandez-Lima, Fenfei Leng
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130478 (2015)
The mammalian high mobility group protein AT-hook 2 (HMGA2) is a chromosomal architectural transcription factor involved in cell transformation and oncogenesis. It consists of three positively charged "AT-hooks" and a negatively charged C-terminus. S
Externí odkaz:
https://doaj.org/article/8209ad5dfdc14a1081ba9a391d91adc4
Autor:
Hernández-Martínez, Gabriela, Ares, Miguel A., Rosales-Reyes, Roberto, Soria-Bustos, Jorge, Antonio Yañez-Santos, Jorge, Cedillo, María L., Girón, Jorge A., Martínez-Laguna, Ygnacio, Fenfei Leng, Ibarra, J. Antonio, De la Cruz, Miguel A.
Publikováno v:
MSphere; May2024, Vol. 9 Issue 5, p1-15, 15p
Autor:
Eddy E. Alfonso, Zifang Deng, Daniel Boaretto, Becky L. Hood, Stefan Vasile, Layton H. Smith, Jeremy W. Chambers, Prem Chapagain, Fenfei Leng
Publikováno v:
ACS Pharmacology & Translational Science. 5:932-944
Bacterial DNA gyrase, a type IIA DNA topoisomerase that plays an essential role in bacterial DNA replication and transcription, is a clinically validated target for discovering and developing new antibiotics. In this article, based on a supercoiling-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce647a75e9c077c0e118928d51be37a
https://doi.org/10.1021/acsptsci.2c00113
https://doi.org/10.1021/acsptsci.2c00113
Autor:
Kevin Jeanne Dit Fouque, Sarah N. Sipe, Alyssa Garabedian, German Mejia, Linjia Su, Md Lokman Hossen, Prem P. Chapagain, Fenfei Leng, Jennifer S. Brodbelt, Francisco Fernandez-Lima
Publikováno v:
J Am Soc Mass Spectrom
The mammalian high mobility group protein AT-hook 2 (HMGA2) is an intrinsically disordered DNA-binding protein expressed during embryogenesis. In the present work, the conformational and binding dynamics of HMGA2 and HMGA2 in complex with a 22-nt (DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3389070603403b63c2d1910778e53dab
https://doi.org/10.1021/jasms.2c00101
https://doi.org/10.1021/jasms.2c00101