Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Fendt SM"'
Autor:
Nowak-Sliwinska, P, Alitalo, K, Allen, E, Anisimov, A, Aplin, AC, Auerbach, R, Augustin, HG, Bates, DO, van Beijnum, JR, Bender, RHF, Bergers, G, Bikfalvi, A, Bischoff, J, Böck, BC, Brooks, PC, Bussolino, F, Cakir, B, Carmeliet, P, Castranova, D, Cimpean, AM, Cleaver, O, Coukos, G, Davis, GE, De Palma, M, Dimberg, A, Dings, RPM, Djonov, V, Dudley, AC, Dufton, NP, Fendt, SM, Ferrara, N, Fruttiger, M, Fukumura, D, Ghesquière, B, Gong, Y, Griffin, RJ, Harris, AL, Hughes, CCW, Hultgren, NW, Iruela-Arispe, ML, Irving, M, Jain, RK, Kalluri, R, Kalucka, J, Kerbel, RS, Kitajewski, J, Klaassen, I, Kleinmann, HK, Koolwijk, P, Kuczynski, E, Kwak, BR, Marien, K, Melero-Martin, JM, Munn, LL, Nicosia, RF, Noel, A, Nurro, J, Olsson, AK, Petrova, TV, Pietras, K, Pili, R, Pollard, JW, Post, MJ, Quax, PHA, Rabinovich, GA, Raica, M, Randi, AM, Ribatti, D, Ruegg, C, Schlingemann, RO, Schulte-Merker, S, Smith, LEH, Song, JW, Stacker, SA, Stalin, J, Stratman, AN, Van de Velde, M, van Hinsbergh, VWM, Vermeulen, PB, Waltenberger, J, Weinstein, BM, Xin, H, Yetkin-Arik, B
Publikováno v:
Nowak-Sliwinska, P; Alitalo, K; Allen, E; Anisimov, A; Aplin, AC; Auerbach, R; et al.(2018). Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis, 21(3), 425-532. doi: 10.1007/s10456-018-9613-x. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/7q90m2m9
© 2018, The Author(s). The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::f2b0290b866c361f116c065e6486e5d6
http://www.escholarship.org/uc/item/7q90m2m9
http://www.escholarship.org/uc/item/7q90m2m9
Autor:
Talebi, A, Dehairs, J, Rambow, F, Rogiers, A, Nittner, D, Derua, R, Vanderhoydonc, F, Duarte, JAG, Bosisio, F, Van den Eynde, K, Nys, K, Pérez, MV, Agostinis, P, Waelkens, E, Van den Oord, J, Fendt, SM, Marine, JC, Swinnen, JV
Whereas significant anti-tumor responses are observed in most BRAFV600E-mutant melanoma patients exposed to MAPK-targeting agents, resistance almost invariably develops. Here, we show that in therapy-responsive cells BRAF inhibition induces downregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1131::4df29f800a85a03d6b5e65b3e8174356
https://lirias.kuleuven.be/handle/123456789/584843
https://lirias.kuleuven.be/handle/123456789/584843
Autor:
Buescher, JM, Antoniewicz, MR, Boros, LG, Burgess, SC, Brunengraber, H, Clish, CB, DeBerardinis, RJ, Feron, O, Frezza, C, Ghesquiere, B, Gottlieb, E, Hiller, K, Jones, RG, Kamphorst, JJ, Kibbey, RG, Kimmelman, AC, Locasale, JW, Lunt, SY, Maddocks, ODK, Malloy, C, Metallo, CM, Meuillet, EJ, Munger, J, Nöh, K, Rabinowitz, JD, Ralser, M, Sauer, U, Stephanopoulos, G, St-Pierre, J, Tennant, DA, Wittmann, C, Vander Heiden, MG, Vazquez, A, Vousden, K, Young, JD, Zamboni, N, Fendt, SM
Publikováno v:
Buescher, JM; Antoniewicz, MR; Boros, LG; Burgess, SC; Brunengraber, H; Clish, CB; et al.(2015). A roadmap for interpreting13C metabolite labeling patterns from cells. Current Opinion in Biotechnology, 34, 189-201. doi: 10.1016/j.copbio.2015.02.003. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5fr4f1fn
© 2015 Elsevier Ltd. Measuring intracellular metabolism has increasingly led to important insights in biomedical research.13C tracer analysis, although less information-rich than quantitative13C flux analysis that requires computational data integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4ec18484cc9545e4a28cce972d8bf60d
http://www.escholarship.org/uc/item/5fr4f1fn
http://www.escholarship.org/uc/item/5fr4f1fn
Immune cell function is tightly regulated by cellular metabolism, which in turn is strongly linked to the nutrient availability in the microenvironment surrounding the cells. This link is critical for effector CD8+ T cells which, after activation, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1131::75d6043e5ad0d51b486810896861579b
https://lirias.kuleuven.be/handle/123456789/628733
https://lirias.kuleuven.be/handle/123456789/628733
Publikováno v:
Metabolic Signaling ISBN: 9781493987689
Here, we offer you a high-throughput assay to measure the ATP synthesis capacity in cells or isolated mitochondria. More specifically, the assay is linked to the mitochondrial' electron transport chain components of your interest being either through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a0fa6091cbcc237cdc12560e5734b7
https://lirias.kuleuven.be/handle/123456789/628568
https://lirias.kuleuven.be/handle/123456789/628568
Autor:
Broekaert, Dorien, Fendt, Sarah-Maria
Metabolic alterations are a hallmark of cancer. While determining metabolic changes in vitro has delivered valuable insight into the metabolism of cancer cells, it emerges that determining the in vivo metabolism adds an additional layer of informatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1131::44005543bceaf4894a55abfc7ed2643d
https://lirias.kuleuven.be/handle/123456789/628727
https://lirias.kuleuven.be/handle/123456789/628727
Autor:
Vanthienen W; Center for Microbiology, VIB, Leuven-Heverlee, Belgium.; Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium., Fernández-García J; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Baietti MF; TRACE PDX Platform, Laboratory of RNA Cancer Biology, LKI Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Claeys E; TRACE PDX Platform, Laboratory of RNA Cancer Biology, LKI Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Van Leemputte F; Center for Microbiology, VIB, Leuven-Heverlee, Belgium.; Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium., Nguyen L; Screening Core, VIB, Ghent, Belgium.; Centre for Bioassay Development and Screening (C-BIOS), Ghent University, Ghent, Belgium., Goossens V; Screening Core, VIB, Ghent, Belgium.; Centre for Bioassay Development and Screening (C-BIOS), Ghent University, Ghent, Belgium., Deparis Q; Center for Microbiology, VIB, Leuven-Heverlee, Belgium.; Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium., Broekaert D; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Vlayen S; LKI Leuven Cancer Institute Leuven, KU Leuven, Leuven, Belgium., Audenaert D; Screening Core, VIB, Ghent, Belgium.; Centre for Bioassay Development and Screening (C-BIOS), Ghent University, Ghent, Belgium., Delforge M; LKI Leuven Cancer Institute Leuven, KU Leuven, Leuven, Belgium., D'Amuri A; Anatomic Pathology Unit, 'A. Perrino' Hospital, Brindisi, Italy., Van Zeebroeck G; Center for Microbiology, VIB, Leuven-Heverlee, Belgium.; Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium., Leucci E; TRACE PDX Platform, Laboratory of RNA Cancer Biology, LKI Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Fendt SM; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Thevelein JM; Center for Microbiology, VIB, Leuven-Heverlee, Belgium.; Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven-Heverlee, Belgium.; NovelYeast bv, Bio-Incubator, BIO4, Leuven-Heverlee, Belgium.
Publikováno v:
Frontiers in oncology [Front Oncol] 2024 Aug 22; Vol. 14, pp. 1411983. Date of Electronic Publication: 2024 Aug 22 (Print Publication: 2024).
Autor:
Scolaro T; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Manco M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Pecqueux M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Amorim R; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium.; Life and Health Sciences Research Institute, School of Medicine, University of Minho, Campus de Gualtar, Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Trotta R; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Van Acker HH; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Van Haele M; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Shirgaonkar N; Laboratory of Precision Oncology and Cancer Evolution, Genome Institute of Singapore, A*STAR, Singapore, Singapore., Naulaerts S; Laboratory for Cell Stress & Immunity (CSI), Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium., Daniluk J; Laboratory of Ion Channel Research (LICR), VIB-KU Leuven Centre for Brain & Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Prenen F; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Varamo C; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Ponti D; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Medical-Surgical Sciences and Biotechnologies, University of Rome Sapienza, Latina, Italy., Doglioni G; Laboratory of Cellular Metabolism and Metabolic Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Ferreira Campos AM; Laboratory of Cellular Metabolism and Metabolic Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Fernandez Garcia J; Laboratory of Cellular Metabolism and Metabolic Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Radenkovic S; Metabolomics Core Facility, Center for Cancer Biology, VIB, Leuven, Belgium.; Metabolomics Core Facility, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Rouhi P; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Beatovic A; Unicle Biomedical Data Science, Leuven, Belgium., Wang L; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Department of Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Wang Y; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Department of Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Tzoumpa A; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Antoranz A; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Sargsian A; Translation Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Di Matteo M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Berardi E; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Goveia J; Unicle Biomedical Data Science, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Ghesquière B; Metabolomics Core Facility, Center for Cancer Biology, VIB, Leuven, Belgium.; Metabolomics Core Facility, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Roskams T; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Soenen S; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Voets T; Laboratory of Ion Channel Research (LICR), VIB-KU Leuven Centre for Brain & Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Manshian B; Translation Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Garg AD; Laboratory for Cell Stress & Immunity (CSI), Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium., DasGupta R; Laboratory of Precision Oncology and Cancer Evolution, Genome Institute of Singapore, A*STAR, Singapore, Singapore., Topal B; Department of Visceral Surgery, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium. massimiliano.mazzone@kuleuven.vib.be.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium. massimiliano.mazzone@kuleuven.vib.be.
Publikováno v:
Nature cancer [Nat Cancer] 2024 Aug; Vol. 5 (8), pp. 1206-1226. Date of Electronic Publication: 2024 Jun 06.
Autor:
Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000 Leuven, Belgium; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000 Leuven, Belgium. Electronic address: sarah-maria.fendt@kuleuven.be.
Publikováno v:
Cell [Cell] 2024 Jul 25; Vol. 187 (15), pp. 3824-3828.
Autor:
Krieg S; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Herestraat, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat, Leuven, Belgium., Fernandes SI; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Herestraat, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat, Leuven, Belgium., Kolliopoulos C; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Herestraat, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat, Leuven, Belgium., Liu M; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Herestraat, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat, Leuven, Belgium., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Herestraat, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat, Leuven, Belgium.
Publikováno v:
Cancer discovery [Cancer Discov] 2024 Jun 03; Vol. 14 (6), pp. 934-952.