Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fen-Ni Fu"'
Autor:
Petr O Ilyinskii, Grigoriy I Kovalev, Conlin P O'Neil, Christopher J Roy, Alicia M Michaud, Natalia M Drefs, Mikhail A Pechenkin, Fen-Ni Fu, Lloyd P M Johnston, Dmitry A Ovchinnikov, Takashi Kei Kishimoto
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197694 (2018)
We previously reported that synthetic vaccine particles (SVP) encapsulating antigens and TLR agonists resulted in augmentation of immune responses with minimal production of systemic inflammatory cytokines. Here we evaluated two different polymer for
Externí odkaz:
https://doaj.org/article/9f01f61eeda54a439de2914fa8f41d1c
Autor:
Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-ni Fu, Derek VanDyke, Peter G. Traber, Jamie B. Spangler, Sheldon S. Leung, Petr O. Ilyinskii
Low dose IL-2 therapy and IL-2 molecules engineered to be selective for the high affinity IL-2 receptor have been shown to expand Tregs in vivo, and, in the case of low dose IL-2 therapy, has demonstrated promising therapeutic benefit in autoimmune d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be2d4887a24da1329f57ba27cffe21e8
https://doi.org/10.1101/2023.05.15.540840
https://doi.org/10.1101/2023.05.15.540840
Autor:
Lloyd Johnston, Natalia M. Drefs, Christopher J. Roy, Mikhail A. Pechenkin, Takashi Kishimoto, Fen-Ni Fu, Grigoriy I. Kovalev, Alicia M. Michaud, Conlin O'neil, Dmitry A. Ovchinnikov, Petr O. Ilyinskii
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197694 (2018)
PLoS ONE
PLoS ONE
We previously reported that synthetic vaccine particles (SVP) encapsulating antigens and TLR agonists resulted in augmentation of immune responses with minimal production of systemic inflammatory cytokines. Here we evaluated two different polymer for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b73382edb88c74135daab612c2c3f85
https://doi.org/10.1371/journal.pone.0197694
https://doi.org/10.1371/journal.pone.0197694
Autor:
Daniel Ferrari, Robert LaMothe, Pallavi Kolte, Aaron Griset, Conlin O’Neil, Thomas Leland, Fen-ni Fu, Nelly Viseux, Lloyd Johnston, Takashi K. Kishimoto, Roberto Maldonado
Publikováno v:
The Journal of Immunology. 200:55.44-55.44
We have shown that treatment with biodegradable tolerogenic nanoparticles carrying rapamycin (synthetic vaccine particles, SVP) and antigen (inside the particles or admixed) induces durable, antigen-specific immune tolerance even in the presence of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47e2d8c136cdcc9eaa624b9153c117cf
https://doi.org/10.4049/jimmunol.200.supp.55.44
https://doi.org/10.4049/jimmunol.200.supp.55.44
Publikováno v:
Biophysical Chemistry. 99:17-29
Botulinum neurotoxin (BoNT) is an extremely toxic protein to animals and humans. In its mode of action, one of its subunits mediates its translocation by integrating itself into the membrane bilayer. We have examined the membrane channel activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9427fcbbd8027b55a791be2733b2286
https://doi.org/10.1016/s0301-4622(02)00135-7
https://doi.org/10.1016/s0301-4622(02)00135-7
Publikováno v:
Journal of Protein Chemistry. 18:29-38
Clostridium botulinum causes the food poisoning disease botulism by producing botulinum neurotoxin, the most potent toxin known. The neurotoxin is produced along with a group of neurotoxin-associated proteins, or NAPs, which protect it from the low p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5abbbea0ff067ee99145217fb1abd2
https://doi.org/10.1023/a:1020691215056
https://doi.org/10.1023/a:1020691215056
Publikováno v:
Biochemistry. 37:5267-5278
Zn2+-protease activity of botulinum neurotoxin causes the blockage of neurotransmitter release resulting in botulism disease. We have investigated the role of Zn2+ in the biological activity of type A botulinum neurotoxin by removing the bound Zn2+ b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53eb714538f9dd35719b454617c13520
https://doi.org/10.1021/bi9723966
https://doi.org/10.1021/bi9723966
Publikováno v:
Toxicon. 34:737-742
Using primers based on the nucleotide sequence of a neurotoxin binding protein from Type E Clostridium botulinum cultures, an amplified DNA product was obtained through polymerase chain reaction. The 400 base pair amplified DNA fragment was detectabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4d3b41364e7aaab6d4feb30ca59ceb
https://doi.org/10.1016/0041-0101(95)00166-2
https://doi.org/10.1016/0041-0101(95)00166-2
Publikováno v:
Applied Spectroscopy. 48:1432-1441
A Fourier transform infrared spectroscopic method has been developed to analyze protein secondary structure by employing the amide III spectral region (1350–1200 cm−1)· Benefits of using the amide III region have been shown to be substantial. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d71e31b1d1397f964cfc3b8a8683f1f
https://doi.org/10.1366/0003702944028065
https://doi.org/10.1366/0003702944028065
Publikováno v:
Applied Spectroscopy. 47:98-102
The adsorption behavior of lysozyme and immunoglobulin G (IgG) onto a ZnSe crystal surface has been detected by the FT-IR/ATR technique. With this technique we are able to detect the protein adsorption process at a very low concentration (0.0005 mg/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad65509a5ba88baa5c50d216cc0049b
https://doi.org/10.1366/0003702934048451
https://doi.org/10.1366/0003702934048451