Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fen Ju Hu"'
Autor:
Yih-Ru Wu, Kuo-Hsuan Chang, Wen-Teng Chang, Ya-Chin Hsiao, Hsuan-Chu Hsu, Pei-Ru Jiang, Yi-Chun Chen, Chih-Ying Chao, Yi-Chung Chang, Bo-Hsun Lee, Fen-Ju Hu, Wan-Ling Chen, Guey-Jen Lee-Chen, Chiung-Mei Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82001 (2013)
Genetic variants of leucine-rich repeat kinase 2 (LRRK2) were reported to alter the risk for Parkinson's disease (PD). However, the genetic spectrum of LRRK2 variants has not been clearly disclosed yet in Taiwanese population. Herein, we sequenced LR
Externí odkaz:
https://doaj.org/article/ce2116ffd7694496b9801d86947510a4
Autor:
Yi-Chun Chen1, Fen-Ju Hu2, Phoebe Chen3, Yih-Ru Wu1, Hsiu-Chuan Wu1, Sien-Tsong Chen1, Guey-Jen Lee-Chen2 t43019@ntnu.edu.tw, Chiung-Mei Chen1 cmchen@adm.cgmh.org.tw
Publikováno v:
BMC Neurology. 2010, Vol. 10, p41-48. 8p.
Autor:
Tsu Wei Wang, Yih-Ru Wu, Chih-Ying Chao, I-Cheng Chen, Hsin Yi Chang, Fen-Ju Hu, Chih-Hsin Lin, Li-Ching Lee, Yi-Tsun Chen, Ya-Chin Hsiao, Ya-Tang Chen, Hsueh Fen Juan, Chiung-Mei Chen, Guey Jen Lee-Chen
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156:720-729
Mutations in ATP13A2 have been reported to associate with Parkinson's disease (PD). This study investigates the contribution of genetic variants in ATP13A2 to Taiwanese PD. ATP13A2 cDNA fragments from 65 early onset PD (onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae44e0ccd89bd8613fc5d77756c03073
https://doi.org/10.1002/ajmg.b.31214
https://doi.org/10.1002/ajmg.b.31214
Autor:
Guey Jen Lee-Chen, Hon Chung Fung, Chih Ying Chao, Long Sun Ro, Fen Ju Hu, Yi-Chun Chen, Ya Chin Hsiao, Chiung Mei Chen, Yih Ru Wu
Publikováno v:
Clinica Chimica Acta. 411:955-958
Background Impaired ubiquitin–proteasome system function may contribute to the pathogenesis of Parkinson's disease (PD). Methods We conducted a case–control study in a cohort of 517 PD cases and 518 ethnically matched controls to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60dea3eb557d9c7ad5efd6e97322d9
https://doi.org/10.1016/j.cca.2010.03.013
https://doi.org/10.1016/j.cca.2010.03.013
Autor:
Fen Ju Hu, Chun Che Chu, Yi-Chun Chen, Chiung Mei Chen, Hung Chou Kuo, Hsiu Chuan Wu, Sien Tsong Chen, Guey Jen Lee-Chen, Shan Jin Ryu, Yih Ru Wu
Publikováno v:
Clinica Chimica Acta. 408:128-132
To determine the interaction effect between APOE polymorphism and lipid concentrations and alcohol use on spontaneous deep intracerebral hemorrhage (SDICH) risks.We enrolled 217 SDICH patients and 280 controls. Anthropometrics, personal history, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3551e6d0a01e545b1f5522459c174a
https://doi.org/10.1016/j.cca.2009.08.004
https://doi.org/10.1016/j.cca.2009.08.004
Autor:
Ya Fen Cheng, Tzu Jung Chuang, Fen Ju Hu, Yi-Chun Chen, Chiung Mei Chen, Yih Ru Wu, Guey Jen Lee-Chen
Publikováno v:
Neuroscience Letters. 435:219-222
Endoplasmic reticulum (ER) stress induced by misfolded proteins has been implicated in Parkinson's disease (PD) pathogenesis. A malfunction of unfolded protein response (UPR) to ER stress can result in PD as well as other neurodegenerative diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1462d29db105c6b1589b46a0849d3e98
https://doi.org/10.1016/j.neulet.2008.02.039
https://doi.org/10.1016/j.neulet.2008.02.039
Autor:
Yih Ru Wu, Hsiu Kuan Wang, Chiung Mei Chen, Jun Cheng Lin, Guey Jen Lee-Chen, Yuying Hsu, Fen Ju Hu, Hon Chung Fung, Wen Chuin Hsu, Hai Pei Hsu
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 24:104-110
Background: Inflammatory events may contribute to the pathogenesis of dementia and interleukin-1 (IL-1) may exert both neurotoxic and neuroprotective effects. We investigated whether IL-1α –889 C/T and IL-1β –511 C/T promoter polymorphisms are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3b11325dcef057bc2b647aebcf8517
https://doi.org/10.1159/000104829
https://doi.org/10.1159/000104829
Autor:
I-Hsin Feng, Yih-Ru Wu, Yu-Yun Lin, Fen-Ju Hu, Kuo-Hsuan Chang, Rong-Kuo Lyu, Chiung-Mei Chen, Guey Jen Lee-Chen, Huiling Chan
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :300-304
Inflammatory events may contribute to the pathogenesis of Parkinson's disease (PD). We conducted a case-control study in a cohort of 369 PD cases and another cohort of 326 ethnically matched controls to investigate the association of tumor necrosis f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451096168d7374bf72e58e97d85811f8
https://doi.org/10.1002/ajmg.b.30435
https://doi.org/10.1002/ajmg.b.30435
Autor:
Chih-Ying Chao, Chiung-Mei Chen, Guey Jen Lee-Chen, Yih-Ru Wu, Kuo-Hsuan Chang, Yi-Chun Chen, Fen-Ju Hu, Yen-Tzu Liu, I-Cheng Chen, Rong-Kuo Lyu
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :458-462
Both of environmental and genetic factors confer vulnerability to Parkinson's disease (PD). NR4A2 (Nurr1), a member of the steroid/thyroid hormone nuclear receptor superfamily, is essential for the neurogenesis and differentiation of dopaminergic neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfb9dc6c737fb0a58a8fc211f09b956
https://doi.org/10.1002/ajmg.b.30476
https://doi.org/10.1002/ajmg.b.30476
Autor:
Chun Che Chu, Guey Jen Lee-Chen, Chin Chang Huang, Hung Chou Kuo, Chia Wei Liou, Fen Ju Hu, Chiung Mei Chen
Publikováno v:
Journal of the neurological sciences. 278(1-2)
article i nfo Article history: Background: Oculopharyngeal muscular dystrophy (OPMD) is a late onset autosomal dominant muscle disorder. OPMD is caused by a short trinucleotide repeat expansion encoding an expanded polyalanine tract in the polyadenyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46251163a970cae5c65403398aaabece
https://pubmed.ncbi.nlm.nih.gov/19101703
https://pubmed.ncbi.nlm.nih.gov/19101703