Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Femke Valkenburg"'
Autor:
Debby Van Dam, Femke Valkenburg, Kristof Van Kolen, Isabel Pintelon, Jean-Pierre Timmermans, Peter Paul De Deyn
Publikováno v:
Life, Vol 13, Iss 10, p 2088 (2023)
Background: The Tau58/2 and Tau58/4 mouse lines expressing 0N4R tau with a P301S mutation mimic aspects of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). In a side-by-side comparison, we report the age-dependent developme
Externí odkaz:
https://doaj.org/article/6c1945a425ec48379ee799912401d6bb
Pentylenetetrazole-induced Seizure Susceptibility in the Tau58/4 Transgenic Mouse Model of Tauopathy
Publikováno v:
Neuroscience
Neuroscience, 425, 112-122. PERGAMON-ELSEVIER SCIENCE LTD
Neuroscience, 425, 112-122. PERGAMON-ELSEVIER SCIENCE LTD
In several tauopathies such as Alzheimer's disease (AD), an increased incidence of seizures is observed. Tau, one of the major proteins implicated in AD pathology, is an important regulator of neural network excitability and might participate in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528a43296421dee8f8668d3cfe925a5c
https://doi.org/10.1016/j.neuroscience.2019.11.007
https://doi.org/10.1016/j.neuroscience.2019.11.007
Autor:
Debby Van Dam, Femke Valkenburg, Betty E Hornix, Xingdong Zhou, Ietje Mantingh-Otter, Bart J. L. Eggen, Muriel Mari, Zhuoran Yin, Erik Boddeke, Fulvio Reggiori, Peter Paul De Deyn
Publikováno v:
Journal of Alzheimer’s Disease, 60(s1), S41-S57. IOS Press
Yin, Z, Valkenburg, F, Hornix, B E, Mantingh-Otter, I, Zhou, X, Mari, M, Reggiori, F, Van Dam, D, Eggen, B J L, De Deyn, P P & Boddeke, E 2017, ' Progressive Motor Deficit is Mediated by the Denervation of Neuromuscular Junctions and Axonal Degeneration in Transgenic Mice Expressing Mutant (P301S) Tau Protein ', Journal of Alzheimer's Disease, vol. 60, no. s1, pp. S41-S57 . https://doi.org/10.3233/JAD-161206
Journal of Alzheimer's disease
Yin, Z, Valkenburg, F, Hornix, B E, Mantingh-Otter, I, Zhou, X, Mari, M, Reggiori, F, Van Dam, D, Eggen, B J L, De Deyn, P P & Boddeke, E 2017, ' Progressive Motor Deficit is Mediated by the Denervation of Neuromuscular Junctions and Axonal Degeneration in Transgenic Mice Expressing Mutant (P301S) Tau Protein ', Journal of Alzheimer's Disease, vol. 60, no. s1, pp. S41-S57 . https://doi.org/10.3233/JAD-161206
Journal of Alzheimer's disease
Tauopathies include a variety of neurodegenerative diseases associated with the pathological aggregation of hyperphosphorylated tau, resulting in progressive cognitive decline and motor impairment. The underlying mechanism for motor deficits related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ae5ad1898f680883c788f6cb2bb7b0
https://doi.org/10.3233/jad-161206
https://doi.org/10.3233/jad-161206
Autor:
Annemie Van der Linden, Debby Van Dam, Stefanie Dedeurwaerdere, Nora Barriche, Stephan Missault, Peter Paul De Deyn, Femke Valkenburg, Steven Staelens, Leonie Wyffels, Marleen Verhoye, Ines Blockx, Glenn De Pauw, Stephanie Aertgeerts, Jeroen Verhaeghe, Cynthia Anckaerts, Steven Deleye
Publikováno v:
Journal of neurotrauma
Journal of Neurotrauma, 36(5). MARY ANN LIEBERT, INC
Journal of Neurotrauma, 36(5). MARY ANN LIEBERT, INC
There is currently a lack of prognostic biomarkers to predict the different sequelae following traumatic brain injury (TBI). The present study investigated the hypothesis that subacute neuroinflammation and microstructural changes correlate with chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545d0d8588de094fb16eb6c77baf33e0
https://hdl.handle.net/10067/1529590151162165141
https://hdl.handle.net/10067/1529590151162165141
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f097d587a575b8d60fd1e64e073098b8
https://doi.org/10.1016/j.jalz.2017.07.565
https://doi.org/10.1016/j.jalz.2017.07.565