Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Femke M. S. de Vrij"'
Autor:
Eleanor M. Marshall, Lisa Bauer, Tessa Nelemans, Syriam Sooksawasdi Na Ayudhya, Feline Benavides, Kristina Lanko, Femke M. S. de Vrij, Steven A. Kushner, Marion Koopmans, Debby van Riel, Barry Rockx
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract West Nile virus (WNV) and Usutu virus (USUV) are closely related flaviviruses with differing capacities to cause neurological disease in humans. WNV is thought to use a transneural route of neuroinvasion along motor neurons and causes severe
Externí odkaz:
https://doaj.org/article/2adf47848f9941c6940144ed51cf2fd3
Autor:
Lisa Bauer, Melanie Rissmann, Feline F. W. Benavides, Lonneke Leijten, Peter van Run, Lineke Begeman, Edwin J. B. Veldhuis Kroeze, Bas Lendemeijer, Hilde Smeenk, Femke M. S. de Vrij, Steven A. Kushner, Marion P. G. Koopmans, Barry Rockx, Debby van Riel
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with various neurological complications. Although the mechanism is not fully understood, several studies have shown that neuroinflammation occurs in the acu
Externí odkaz:
https://doaj.org/article/4da7ab53165f4227aaa89716e6413f8b
Autor:
Kristel N. Eigenhuis, Hedda B. Somsen, Mark van der Kroeg, Hilde Smeenk, Anne L. Korporaal, Steven A. Kushner, Femke M. S. de Vrij, Debbie L. C. van den Berg
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Human brain organoid technology has the potential to generate unprecedented insight into normal and aberrant brain development. It opens up a developmental time window in which the effects of gene or environmental perturbations can be experimentally
Externí odkaz:
https://doaj.org/article/aa6e6d8657714516b4ada2e38f03bbef
Autor:
Lisa Bauer, Bas Lendemeijer, Lonneke Leijten, Carmen W. E. Embregts, Barry Rockx, Steven A. Kushner, Femke M. S. de Vrij, Debby van Riel
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Infections with the recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are often associated with neurological complications. Evidence suggests that SARS-CoV-2 enters the brain via the olfactory nerve; however, SARS-CoV-2 is
Externí odkaz:
https://doaj.org/article/80ca070663ec4006b8a70f60c0983824
Autor:
Gustavo A. Higuera, Grazia Iaffaldano, Meiwand Bedar, Guy Shpak, Robin Broersen, Shashini T. Munshi, Catherine Dupont, Joost Gribnau, Femke M. S. de Vrij, Steven A. Kushner, Chris I. De Zeeuw
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Abstract The directed differentiation of patient-derived induced pluripotent stem cells into cell-type specific neurons has inspired the development of therapeutic discovery for neurodegenerative diseases. Many forms of ataxia result from degeneratio
Externí odkaz:
https://doaj.org/article/86d10d54ca4343e8a9ee5b3e195133a2
Autor:
Fatih Anfasa, Jurre Y. Siegers, Mark van der Kroeg, Noreen Mumtaz, V. Stalin Raj, Femke M. S. de Vrij, W. Widagdo, Gülsah Gabriel, Sara Salinas, Yannick Simonin, Chantal Reusken, Steven A. Kushner, Marion P. G. Koopmans, Bart Haagmans, Byron E. E. Martina, Debby van Riel
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT Recent Zika virus (ZIKV) infections have been associated with a range of neurological complications, in particular congenital microcephaly. Human neural progenitor cells (hNPCs) are thought to play an important role in the pathogenesis of mi
Externí odkaz:
https://doaj.org/article/7de9006b5bb9498794ea49c3ad3ebc00
Autor:
Rossella, Avagliano Trezza, Monica, Sonzogni, Stijn N V, Bossuyt, F Isabella, Zampeta, A Mattijs, Punt, Marlene, van den Berg, Diana C, Rotaru, Linda M C, Koene, Shashini T, Munshi, Jeffrey, Stedehouder, Johan M, Kros, Mark, Williams, Helen, Heussler, Femke M S, de Vrij, Edwin J, Mientjes, Geeske M, van Woerden, Steven A, Kushner, Ben, Distel, Ype, Elgersma
Publikováno v:
Nature neuroscience. 22(8)
Mutations affecting the gene encoding the ubiquitin ligase UBE3A cause Angelman syndrome. Although most studies focus on the synaptic function of UBE3A, we show that UBE3A is highly enriched in the nucleus of mouse and human neurons. We found that th