Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Femke Anouska Heinsen"'
Autor:
Henrik Knecht, Sven C Neulinger, Femke Anouska Heinsen, Carolin Knecht, Anke Schilhabel, Ruth A Schmitz, Alexandra Zimmermann, Vitor Martins dos Santos, Manuel Ferrer, Philip C Rosenstiel, Stefan Schreiber, Anette K Friedrichs, Stephan J Ott
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89417 (2014)
Clostridium difficile infections are an emerging health problem in the modern hospital environment. Severe alterations of the gut microbiome with loss of resistance to colonization against C. difficile are thought to be the major trigger, but there i
Externí odkaz:
https://doaj.org/article/c010fa2eacee4e30a735966fc5c9e554
Autor:
Martin Pech, Markus Weckmann, Inke R König, Andre Franke, Femke-Anouska Heinsen, Brian Oliver, Isabell Ricklefs, Oliver Fuchs, Klaus Rabe, Gesine Hansen, Erika V Mutius, Matthias V Kopp, ALLIANCE-study group
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0205275 (2018)
Human rhinovirus infection (HRVI) plays an important role in asthma exacerbations and is thought to be involved in asthma development during early childhood. We hypothesized that HRVI causes differential DNA methylation and subsequently differential
Externí odkaz:
https://doaj.org/article/a0db5db5a191471e8a5e59c41b131414
Autor:
Wolfgang Lieb, Friederike Flachsbart, Femke-Anouska Heinsen, Paul Datlinger, Wolfram Klapper, Jonas Mengel-From, Andre Franke, Janina Dose, Silke Szymczak, Almut Nebel, Stefan Schreiber, Geetha Venkatesh, Robert Häsler, Christoph Bock, Guillermo G. Torres, Marianne Nygaard, Kaare Christensen
Publikováno v:
Human Molecular Genetics
Szymczak, S, Dose, J, Torres, G G, Heinsen, F-A, Venkatesh, G, Datlinger, P, Nygaard, M, Mengel-From, J, Flachsbart, F, Klapper, W, Christensen, K, Lieb, W, Schreiber, S, Häsler, R, Bock, C, Franke, A & Nebel, A 2020, ' DNA methylation QTL analysis identifies new regulators of human longevity ', Human Molecular Genetics, vol. 29, no. 7, pp. 1154-1167 . https://doi.org/10.1093/hmg/ddaa033
Szymczak, S, Dose, J, Torres, G G, Heinsen, F-A, Venkatesh, G, Datlinger, P, Nygaard, M, Mengel-From, J, Flachsbart, F, Klapper, W, Christensen, K, Lieb, W, Schreiber, S, Häsler, R, Bock, C, Franke, A & Nebel, A 2020, ' DNA methylation QTL analysis identifies new regulators of human longevity ', Human Molecular Genetics, vol. 29, no. 7, pp. 1154-1167 . https://doi.org/10.1093/hmg/ddaa033
Human longevity is a complex trait influenced by both genetic and environmental factors, whose interaction is mediated by epigenetic mechanisms like DNA methylation. Here, we generated genome-wide whole-blood methylome data from 267 individuals, of w
Autor:
Thomas Röder, Daniela Langfeldt, Ryszard Soluch, Femke-Anouska Heinsen, Hanna Domin, Andre Franke, Marc P. Höppner, Nancy Weiland-Bräuer, Cornelia Jaspers, Ateequr Rehman, Thorsten B. H. Reusch, Thomas C. G. Bosch, Malte C. Rühlemann, Tal Dagan, Philipp Rausch, Shauni Doms, Felix Sommer, Ute Hentschel, Sebastian Fraune, Martin T. Jahn, Philip Rosenstiel, Ruth A. Schmitz, John F. Baines, Katja Dierking, Hinrich Schulenburg, Jakob von Frieling, Britt Marie Hermes, Kohar Annie B. Kissoyan, Eva H. Stukenbrock
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-19 (2019)
Microbiome
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, von Frieling, J, Henschel, U, Heinsen, F-A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P, Franke, A, Bosch, T & Baines, J F 2019, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', Microbiome, vol. 7, 133 . https://doi.org/10.1186/s40168-019-0743-1
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, Von Frieling, J, Hentschel, U, Heinsen, F A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P, Franke, A, Bosch, T & Baines, J F 2019, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', Microbiome, vol. 7, 133 . https://doi.org/10.1101/604314, https://doi.org/10.1186/s40168-019-0743-1
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, Von Frieling, J, Humeida, U H, Heinsen, F A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P C, Franke, A, Bosch, T & Baines, J F 2020, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', bioRxiv . https://doi.org/10.1101/604314
Microbiome, 7 (1). Art.Nr. 133.
Microbiome
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, von Frieling, J, Henschel, U, Heinsen, F-A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P, Franke, A, Bosch, T & Baines, J F 2019, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', Microbiome, vol. 7, 133 . https://doi.org/10.1186/s40168-019-0743-1
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, Von Frieling, J, Hentschel, U, Heinsen, F A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P, Franke, A, Bosch, T & Baines, J F 2019, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', Microbiome, vol. 7, 133 . https://doi.org/10.1101/604314, https://doi.org/10.1186/s40168-019-0743-1
Rausch, P, Rühlemann, M, Hermes, B M, Doms, S, Dagan, T, Dierking, K, Domin, H, Fraune, S, Von Frieling, J, Humeida, U H, Heinsen, F A, Höppner, M, Jahn, M T, Jaspers, C, Kissoyan, K A B, Langfeldt, D, Rehman, A, Reusch, T B H, Roeder, T, Schmitz, R A, Schulenburg, H, Soluch, R, Sommer, F, Stukenbrock, E, Weiland-Bräuer, N, Rosenstiel, P C, Franke, A, Bosch, T & Baines, J F 2020, ' Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms ', bioRxiv . https://doi.org/10.1101/604314
Microbiome, 7 (1). Art.Nr. 133.
Background The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution, and development of both players. These interdependencies inspired a new view of multicellular organisms as “m
Autor:
Mie Korslund Wiinblad Crusell, Tue Haldor Hansen, Trine Nielsen, Kristine Højgaard Allin, Malte C. Rühlemann, Peter Damm, Henrik Vestergaard, Christina Rørbye, Niklas Rye Jørgensen, Ole Bjarne Christiansen, Femke-Anouska Heinsen, Andre Franke, Torben Hansen, Jeannet Lauenborg, Oluf Pedersen
Publikováno v:
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F A, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2020, ' Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes ', Frontiers in Cellular and Infection Microbiology, vol. 10, 536282 . https://doi.org/10.3389/fcimb.2020.536282
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology
Background: Offspring of mothers with gestational diabetes mellitus (GDM) have increased risk of developing metabolic disorders as they grow up. Microbial colonization of the newborn gut and environmental exposures affecting the configuration of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10947d08305c869d1e925c321e61aa8
https://vbn.aau.dk/da/publications/25a7eeb4-1380-4408-bdc5-939348402076
https://vbn.aau.dk/da/publications/25a7eeb4-1380-4408-bdc5-939348402076
Autor:
Jürgen Zentek, Temesgen Hailemariam Dadi, Femke-Anouska Heinsen, Britta Siegmund, Robert Pieper, Knut Reinert, Wilfried Vahjen, Laura Pieper, Lukasz Grzeskowiak, Stefan Schwarz, Andre Franke
Background: Clostridium difficile infection (CDI) is an increasing zoonotic health threat and has also been documented as a cause of enteritis outbreaks in neonatal pigs. Furthermore, CDI in neonatal piglets cause changes in microbial gut colonizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddf79a27f5fcc07bb8206edb27ee711
https://doi.org/10.21203/rs.3.rs-17413/v1
https://doi.org/10.21203/rs.3.rs-17413/v1
Autor:
Henrik Vestergaard, Tue H. Hansen, Ole Bjarne Christiansen, Oluf Pedersen, Trine Nielsen, Peter Damm, Malte C. Rühlemann, Mie Crusell, Niklas Rye Jørgensen, Christina Rørbye, Andre Franke, Kristine H. Allin, Jeannet Lauenborg, Femke-Anouska Heinsen, Torben Hansen
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-19 (2018)
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F-A, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, no. 1, 89, pp. 1-19 . https://doi.org/10.1186/s40168-018-0472-x
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F-A, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, 89 . https://doi.org/10.1186/s40168-018-0472-x
Microbiome
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, 89 . https://doi.org/10.1186/s40168-018-0472-x
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F-A, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, no. 1, 89, pp. 1-19 . https://doi.org/10.1186/s40168-018-0472-x
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F-A, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, 89 . https://doi.org/10.1186/s40168-018-0472-x
Microbiome
Crusell, M K W, Hansen, T H, Nielsen, T, Allin, K H, Rühlemann, M C, Damm, P, Vestergaard, H, Rørbye, C, Jørgensen, N R, Christiansen, O B, Heinsen, F, Franke, A, Hansen, T, Lauenborg, J & Pedersen, O 2018, ' Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum ', Microbiome, vol. 6, 89 . https://doi.org/10.1186/s40168-018-0472-x
Background Imbalances of gut microbiota composition are linked to a range of metabolic perturbations. In the present study, we examined the gut microbiota of women with gestational diabetes mellitus (GDM) and normoglycaemic pregnant women in late pre
Autor:
Martin Stanulla, Andre Franke, Michael Forster, Jörn Bethune, Lewis Baker, Femke-Anouska Heinsen, Georg Hemmrich-Stanisak, Martin Schrappe, Priyadarshini Kachroo, Silke Szymczak
Publikováno v:
Epigenomics. 10:133-147
Aim: To determine whether methylation differences between mostly fatal TCF3-HLF and curable TCF3-PBX1 pediatric acute lymphoblastic leukemia subtypes can be associated with differential gene expression and remission. Materials & methods: Five (extrem
Autor:
K Türk, Ateequr Rehman, Matthias Laudes, Karin Schwarz, Georg H. Waetzig, Dominik M. Schulte, Dirk Seegert, Julia K. Keppler, Eva-Maria Theismann, Femke-Anouska Heinsen, Isabelle Relling, Philip Rosenstiel, Stanislav N. Gorb, Esther Appel, Andre Franke, Jörg-Rainer Knipp, Stefan Schreiber, Lennart Lenk, Daniela Fangmann, Sandra Freitag-Wolf, Charles Brenner, Katharina Hartmann
Publikováno v:
Diabetes Care 41 (2018) 3
Diabetes Care, 41(3), 398-405
Diabetes Care, 41(3), 398-405
OBJECTIVE Gut microbiota represent a potential novel target for future prediabetes and type 2 diabetes therapies. In that respect, niacin has been shown to beneficially affect the host-microbiome interaction in rodent models. RESEARCH DESIGN AND METH
Autor:
Martina E. Spehlmann, Thorben Winkler, Stephan J. Ott, Amer Bajrovic, Femke-Anouska Heinsen, Malte C. Rühlemann, Mark Luedde, Andre Franke, Wolfgang Lieb, Norbert Frey
Publikováno v:
ESC Heart Failure. 4:282-290
Aims In spite of current medical treatment approaches, mortality of chronic heart failure (HF) remains high and novel treatment modalities are thus urgently needed. A recent theory proposes a possible impact of the intestinal microbiome on the incide