Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Femke, van Wijk"'
Autor:
Rik J. Verheijden, Mick J. M. van Eijs, Anne M. May, Femke van Wijk, Karijn P. M. Suijkerbuijk
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Immune checkpoint inhibitors (ICIs) have changed perspectives for patients with cancer, but come with severe immune-related adverse events (irAEs). To prevent fatality or chronicity, these irAEs are often promptly treated with high-dose immu
Externí odkaz:
https://doaj.org/article/e1c6b6c6fa3a460c9209924d9b2be987
Autor:
Mick J.M. van Eijs, José J.M. ter Linde, Matthijs J.D. Baars, Mojtaba Amini, Miangela M. Laclé, Eelco C. Brand, Eveline M. Delemarre, Julia Drylewicz, Stefan Nierkens, Rik J. Verheijden, Bas Oldenburg, Yvonne Vercoulen, Karijn P.M. Suijkerbuijk, Femke van Wijk
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107891- (2023)
Summary: Colitis is a prevalent adverse event associated with immune checkpoint inhibitor (ICI) therapy with similarities to inflammatory bowel disease. Incomplete mechanistic understanding of ICI colitis curtails evidence-based treatment. Given the
Externí odkaz:
https://doaj.org/article/275e4beac3b94af3a05ead771f3af228
Autor:
J. N. Juliëtte Pouw, M. A. M. Michel Olde Nordkamp, T. Tessa van Kempen, A. N. Arno Concepcion, J. M. Jacob van Laar, F. Femke van Wijk, J. Julia Spierings, E. F. A. Emmerik Leijten, M. Marianne Boes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract In psoriatic arthritis (PsA), predisposing class I HLA alleles, the presence of synovial clonally proliferated CD8 + T cells and autoantibodies all point towards the loss of immune tolerance. However, the key mechanisms that lead to immune d
Externí odkaz:
https://doaj.org/article/2ba36dfe248946678420b6b35b640798
Autor:
Arthur H. van Stigt, Katrien Oude Rengerink, Kitty W. M. Bloemenkamp, Wouter de Waal, Sabine M. P. J. Prevaes, Thuy-My Le, Femke van Wijk, Maaike Nederend, Anneke H. Hellinga, Christianne S. Lammers, Gerco den Hartog, Martijn J. C. van Herwijnen, Johan Garssen, Léon M. J. Knippels, Lilly M. Verhagen, Caroline G. M. de Theije, Alejandro Lopez-Rincon, Jeanette H. W. Leusen, Belinda van’t Land, Louis Bont, PRIMA Initiative Group
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Many studies support the protective effect of breastfeeding on respiratory tract infections. Although infant formulas have been developed to provide adequate nutritional solutions, many components in human milk contributing to the
Externí odkaz:
https://doaj.org/article/8c8cc4d805164a4dacefe3ce7b9559c3
Autor:
Gerdien Mijnheer, Nila Hendrika Servaas, Jing Yao Leong, Arjan Boltjes, Eric Spierings, Phyllis Chen, Liyun Lai, Alessandra Petrelli, Sebastiaan Vastert, Rob J de Boer, Salvatore Albani, Aridaman Pandit, Femke van Wijk
Publikováno v:
eLife, Vol 12 (2023)
Autoimmune inflammation is characterized by tissue infiltration and expansion of antigen-specific T cells. Although this inflammation is often limited to specific target tissues, it remains yet to be explored whether distinct affected sites are infil
Externí odkaz:
https://doaj.org/article/7571fb8d41c545a59ee5ff9879ec1345
Autor:
Arjan Boltjes, Anoushka Ashok Kumar Samat, Maud Plantinga, Michal Mokry, Bas Castelijns, Joost F. Swart, Sebastiaan J. Vastert, Menno Creyghton, Stefan Nierkens, Jorg van Loosdregt, Femke van Wijk
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionDendritic cells (DC) are crucial for initiating and shaping immune responses. So far, little is known about the functional specialization of human DC subsets in (local) inflammatory conditions. We profiled conventional (c)DC1, cDC2 and mo
Externí odkaz:
https://doaj.org/article/a89bf43ba6e2488584442c0f47a014ee
Autor:
Judith Wienke, Saskia R. Veldkamp, Eva M. Struijf, Fjodor A. Yousef Yengej, M. Marlot van der Wal, Annet van Royen-Kerkhof, Femke van Wijk
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-resident memory T cells (TRM) are suspected drivers of chronic inflammation, but their induction remains unclear. Since endothelial cells (EC) are obligate interaction partners for T cells trafficking into inflamed tissues, they may play a rol
Externí odkaz:
https://doaj.org/article/2d24555038ab49e1943cb86233e953cd
Autor:
Gerdien Mijnheer, Lisanne Lutter, Michal Mokry, Marlot van der Wal, Rianne Scholman, Veerle Fleskens, Aridaman Pandit, Weiyang Tao, Mark Wekking, Stephin Vervoort, Ceri Roberts, Alessandra Petrelli, Janneke G. C. Peeters, Marthe Knijff, Sytze de Roock, Sebastiaan Vastert, Leonie S. Taams, Jorg van Loosdregt, Femke van Wijk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
T regulatory (Treg) cells can differentiate into effector Treg (eTreg) cells that might be functional in inflammatory diseases. Using RNA sequencing and epigenetic profiling, the authors show that eTreg signatures in juvenile idiopathic arthritis joi
Externí odkaz:
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
Autor:
Lisanne Lutter, Britt Roosenboom, Eelco C. Brand, José J. ter Linde, Bas Oldenburg, Ellen G. van Lochem, Carmen S. Horjus Talabur Horje, Femke van Wijk
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1567-1581 (2021)
Background & Aims: Tissue-resident memory T (Trm) cells, both of the CD4 and CD8 lineage, have been implicated in disease flares in inflammatory bowel disease. However, data are conflicting regarding the profile of human CD8+ Trm cells, with studies
Externí odkaz:
https://doaj.org/article/a4509fd606384f5597875baba536cee4
Autor:
Juliëtte N. Pouw, Michel A. M. Olde Nordkamp, Tessa van Kempen, Arno N. Concepcion, Jacob M. van Laar, Femke van Wijk, Julia Spierings, Emmerik F. A. Leijten, Marianne Boes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e90d847270fa4179828ffe08969ee751