Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Felix W. Friedrich"'
Autor:
Alexandra Rhoden, Felix W. Friedrich, Theresa Brandt, Janice Raabe, Michaela Schweizer, Jana Meisterknecht, Ilka Wittig, Bärbel M. Ulmer, Birgit Klampe, June Uebeler, Angelika Piasecki, Kristina Lorenz, Thomas Eschenhagen, Arne Hansen, Friederike Cuello
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101951- (2021)
Sulforaphane (SFN) is a phytochemical compound extracted from cruciferous plants, like broccoli or cauliflower. Its isothiocyanate group renders SFN reactive, thus allowing post-translational modification of cellular proteins to regulate their functi
Externí odkaz:
https://doaj.org/article/a81f7c0265ef4de595371b05c4cdf846
Autor:
Nico Kresin, Sabrina Stücker, Elisabeth Krämer, Frederik Flenner, Giulia Mearini, Julia Münch, Monica Patten, Charles Redwood, Lucie Carrier, Felix W. Friedrich
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Background: Many forms of hypertrophic cardiomyopathy (HCM) show an increased myofilament Ca2+ sensitivity. This observation has been mainly made in HCM mouse models, myofilament systems, and cardiomyocytes. Studies of multicellular tissues from pati
Externí odkaz:
https://doaj.org/article/9afd9321f0244aeeaedb90d00b1f6ea0
Autor:
Simon Braumann, Tilo Thottakara, Sabrina Stücker, Silke Reischmann-Düsener, Elisabeth Krämer, Julia Groß, Marc N. Hirt, Shirin Doroudgar, Lucie Carrier, Felix W. Friedrich
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background: S100A4 has recently emerged as an important player in cardiac disease, affecting phenotype development in animal models of myocardial infarction and pathological cardiac hypertrophy, albeit it is unclear whether S100A4 exerts a detrimenta
Externí odkaz:
https://doaj.org/article/6c7a86c5281f4704851a5030e728a51d
Autor:
Felix W. Friedrich, Hannieh Sotoud, Birgit Geertz, Silvio Weber, Frederik Flenner, Silke Reischmann, Thomas Eschenhagen, Lucie Carrier, Ali El-Armouche
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 8, Iss C, Pp 87-94 (2015)
Aims: Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy, diastolic dysfunction and increased interstitial fibrosis. Current treatment is based on beta-adrenoceptor (AR) and calcium channel blockers. Since mice deficie
Externí odkaz:
https://doaj.org/article/e8c2dbbdb4be462c88dcc33c4e71d251
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Background: Hypertrophic cardiomyopathy (HCM) patients often present with diastolic dysfunction and a normal to supranormal systolic function. To counteract this hypercontractility, guideline therapies advocate treatment with beta-adrenoceptor and Ca
Externí odkaz:
https://doaj.org/article/f9caa2dc703c45c99447caab8912677d
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Background. Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac muscle disease with left ventricular hypertrophy, interstitial fibrosis and diastolic dysfunction. Increased myofilament Ca2+ sensitivity could be the underlying cause
Externí odkaz:
https://doaj.org/article/b519bb49ef43498eb4e84a49d52c185a
Autor:
Tjark Schwemer, Edzard Schwedhelm, Stefan Blankenberg, Nadine Diermann, Navina Deutscher, Rainer H. Böger, Felix W. Friedrich
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
The purpose of the present study was to assess whether 6-week ranolazine application on top of guideline-based treatment impacts on the arginine/NO pathway and urinary isoprostane 8-iso-PGF2α as marker of oxidative stress in patients directly after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd5dae483226d8950b394dca8caaad2
http://link.springer.com/article/10.1038/s41598-019-42239-1
http://link.springer.com/article/10.1038/s41598-019-42239-1
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Claus F Vogelmeier,1 Joanna Diesing,2 Nils Kossack,2 Marc Pignot,3 Felix W Friedrich4 1Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-Universität Marburg, Marburg, Hessen, Germ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aa7d7c5dcfed24041856f940870f79
https://pubmed.ncbi.nlm.nih.gov/34465988
https://pubmed.ncbi.nlm.nih.gov/34465988
Autor:
Felix W. Friedrich, Nadine Diermann, Stefan Blankenberg, Tjark Schwemer, Susanne Sehner, Lukas Radziwolek, Navina Deutscher
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 24:62-69
Background: Coronary artery disease is the most prevalent manifestation among cardiovascular diseases. Despite modern treatment, risk of ischemic complications in patients with acute coronary syndrome (ACS) remains important. The late Na+ current blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a465d8651ccfb5d947d5fa52ca51d126
https://doi.org/10.1177/1074248418784290
https://doi.org/10.1177/1074248418784290
Autor:
Felix W. Friedrich, Sophie Schobesberger, Thea Koch, Nicole Arlt, Frederik Flenner, Ursula Ravens, Viacheslav O. Nikolaev, Torsten Christ, Mahtab Nasib, Sebastian Stehr
Publikováno v:
Anesthesiology. 128:1175-1186
BackgroundSystemic toxicity of local anesthetics is predominantly complicated by their myocardial toxicity. Especially long-acting local anesthetics exert a negative inotropic effect that has been described at lower concentrations than defined for bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22582195ba2d0ea3f30f945ff45ecda
https://doi.org/10.1097/aln.0000000000002180
https://doi.org/10.1097/aln.0000000000002180