Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Felix Schatter"'
Autor:
Julia U. Sprenger, Maja Köhn, Viacheslav O. Nikolaev, Jonas Herting, Yansong Wang, Ali El-Armouche, Samuel Sossalla, Felix Schatter, Gerd Hasenfuss, Thomas H. Fischer, Jörg Eiringhaus, Markus Zabel
Publikováno v:
Basic Research in Cardiology. 114
Increased late sodium current (late INa) is an important arrhythmogenic trigger in cardiac disease. It prolongs cardiac action potential and leads to an increased SR Ca2+ leak. This study investigates the contribution of Ca2+/Calmodulin-dependent kin
Autor:
Nico Hartmann, Norbert Frey, Gerd Hasenfuss, Jonas Herting, Felix Schatter, Thomas H. Fischer, Steffen Pabel, Samuel Sossalla, Lars S. Maier, Hanna Schotola, Bernhard C. Danner, Jan Gummert, André Renner
Publikováno v:
Heart rhythm. 14(3)
Background Cardiac type 2 ryanodine receptors (RyR2s) play a pivotal role in cellular electrophysiology and contractility. Increased RyR2-mediated diastolic sarcoplasmic reticulum (SR) Ca2+ release is linked to heart failure (HF) and arrhythmias. Dan