Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Felix Scharte"'
Autor:
Vera Göser, Nathalie Sander, Marc Schulte, Felix Scharte, Rico Franzkoch, Viktoria Liss, Olympia E. Psathaki, Michael Hensel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Salmonella typhimurium translocates numerous effectors via its type III secretion system. Here, Göser et al. present a characterisation of selected proteins and their dynamic interaction with Salmonella-containing vacuoles and – induced filaments.
Externí odkaz:
https://doaj.org/article/f77dc81f323c4a3ea8d96c3fbbade3fb
Autor:
Patrick Niekamp, Felix Scharte, Tolulope Sokoya, Laura Vittadello, Yeongho Kim, Yongqiang Deng, Elisabeth Südhoff, Angelika Hilderink, Mirco Imlau, Christopher J. Clarke, Michael Hensel, Christopher G. Burd, Joost C. M. Holthuis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Activation of ESCRT prevents potentially lethal outcomes of minor perturbations in lysosomal integrity. Here authors show that Ca2 + -activated scrambling of sphingomyelin and its cytosolic turnover drives lysosomal repair independently of ESCRT.
Externí odkaz:
https://doaj.org/article/8782aaf4d7804bac8f2c73df7fa64a62
Autor:
Helit Cohen, Claire Hoede, Felix Scharte, Charles Coluzzi, Emiliano Cohen, Inna Shomer, Ludovic Mallet, Sébastien Holbert, Remy Felix Serre, Thomas Schiex, Isabelle Virlogeux-Payant, Guntram A Grassl, Michael Hensel, Hélène Chiapello, Ohad Gal-Mor
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010425 (2022)
Although Salmonella Typhimurium (STM) and Salmonella Paratyphi A (SPA) belong to the same phylogenetic species, share large portions of their genome and express many common virulence factors, they differ vastly in their host specificity, the immune r
Externí odkaz:
https://doaj.org/article/8d55f086a3b845e99fd0afe8f1a6b05a
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009319 (2021)
Salmonella enterica is a common foodborne, facultative intracellular enteropathogen. Human-restricted typhoidal S. enterica serovars Typhi (STY) or Paratyphi A (SPA) cause severe typhoid or paratyphoid fever, while many S. enterica serovar Typhimuriu
Externí odkaz:
https://doaj.org/article/6cb55f3c5b5a4384a5da77df22b73587
Autor:
Emiliano Cohen, Shalevet Azriel, Oren Auster, Adiv Gal, Carmel Zitronblat, Svetlana Mikhlin, Felix Scharte, Michael Hensel, Galia Rahav, Ohad Gal-Mor
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009451 (2021)
Salmonella enterica is a diverse bacterial pathogen and a primary cause of human and animal infections. While many S. enterica serovars present a broad host-specificity, several specialized pathotypes have been adapted to colonize and cause disease i
Externí odkaz:
https://doaj.org/article/b85243ab6e4445efb75ba8db58e69014
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6484 (2021)
Pathogenic intracellular bacteria, parasites and viruses have evolved sophisticated mechanisms to manipulate mammalian host cells to serve as niches for persistence and proliferation. The intracellular lifestyles of pathogens involve the manipulation
Externí odkaz:
https://doaj.org/article/735bfbd3775f46d1830ec6c99a18b02e
Salmonella enterica is a common foodborne, facultative intracellular enteropathogen. Typhoidal S. enterica serovars like Paratyphi A (SPA) are human restricted and cause a severe systemic disease, while many S. enterica serovars like Typhimurium (STM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a4d99cad0786876703680fa9dfae9fb
https://doi.org/10.1101/2022.07.24.501230
https://doi.org/10.1101/2022.07.24.501230
Autor:
Vera Göser, Marc Schulte, Felix Scharte, Rico Franzkoch, Viktoria Liss, Olympia E. Psathaki, Michael Hensel
Bacterial pathogens deliver proteins in temporal and spatial coordinated manner to manipulate mammalian host cells. The facultative intracellular pathogen Salmonella enterica remodels the host endosomal system for survival and proliferation inside ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415824b6420a88f88146e93ff2052c35
https://doi.org/10.21203/rs.3.rs-1681678/v1
https://doi.org/10.21203/rs.3.rs-1681678/v1
Autor:
Helit Cohen, Claire Hoede, Felix Scharte, Charles Coluzzi, Emiliano Cohen, Inna Shomer, Ludovic Mallet, Sébastien Holbert, Remy Felix Serre, Thomas Schiex, Isabelle Virlogeux-Payant, Guntram A. Grassl, Michael Hensel, Hélène Chiapello, Ohad Gal-Mor
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2022, 18 (4), 35 p. ⟨10.1371/journal.ppat.1010425⟩
PLoS Pathogens, 2022, 18 (4), 35 p. ⟨10.1371/journal.ppat.1010425⟩
Although Salmonella Typhimurium (STM) and Salmonella Paratyphi A (SPA) belong to the same phylogenetic species, share large portions of their genome and express many common virulence factors, they differ vastly in their host specificity, the immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4bb2a736e15c0687a0223ae26b475f
https://pubmed.ncbi.nlm.nih.gov/35381053
https://pubmed.ncbi.nlm.nih.gov/35381053
Autor:
Patrick, Niekamp, Felix, Scharte, Tolulope, Sokoya, Laura, Vittadello, Yeongho, Kim, Yongqiang, Deng, Elisabeth, Südhoff, Angelika, Hilderink, Mirco, Imlau, Christopher J, Clarke, Michael, Hensel, Christopher G, Burd, Joost C M, Holthuis
Publikováno v:
Nature communications. 13(1)
Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell viability. Here we report that cells exploit a sphingomyelin-based lysosomal repair pathway that ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71b1f73979ae3e2298731237ae1ace5d
https://pubmed.ncbi.nlm.nih.gov/35388011
https://pubmed.ncbi.nlm.nih.gov/35388011