Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Felix S. Zarudii"'
Autor:
Felix S. Zarudii, A. R. Gimadieva, Akhat G. Mustafin, V. R. Khairullina, Anatoly Ya. Gerchikov
Publikováno v:
Journal of Molecular Graphics and Modelling. 85:198-211
A quantitative structure–activity relationship analysis of the 2-methylquinazolin-4-one and quinazolin-4-imine derivatives, well-known antifolate thymidylate synthase (TYMS) inhibitors, has been performed in the range IC50 = 0.4÷380000.0 nmoL/L us