Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Felix S. Alfonso"'
Autor:
Yuecheng Zhou, Erica Liu, Yang Yang, Felix S. Alfonso, Burhan Ahmed, Kenneth Nakasone, Csaba Forró, Holger Müller, Bianxiao Cui
Publikováno v:
Journal of the American Chemical Society.
Optical recording based on voltage-sensitive fluorescent reporters allows for spatial flexibility of measuring from desired cells, but photobleaching and phototoxicity of the fluorescent labels often limit their sensitivity and recording duration. Vo
Autor:
Erica Liu, Yuecheng Zhou, Felix S. Alfonso, Yang Yang, Burhan Ahmed, Kenneth Nakasone, Victoria Xu, Holger Mueller, Bianxiao Cui
Publikováno v:
Biophysical Journal. 122:540a-541a
Autor:
Burhan Ahmed, Kenneth Nakasone, Dana Griffith, Yuecheng Zhou, Erica Liu, Felix S. Alfonso, Bianxiao Cui, Holger Mueller
Publikováno v:
Biophysical Journal. 122:540a
Autor:
Georges Goetz, Yi Quan, Daniel Palanker, Peng Zhou, Tong Ling, Tiffany Wanshing Huang, Kevin C. Boyle, Felix S. Alfonso
Publikováno v:
Light: Science & Applications, Vol 7, Iss 1, Pp 1-11 (2018)
Light, Science & Applications
Light, Science & Applications
Currently, cellular action potentials are detected using either electrical recordings or exogenous fluorescent probes that sense the calcium concentration or transmembrane voltage. Ca imaging has a low temporal resolution, while voltage indicators ar
Autor:
Holger Müller, Bianxiao Cui, Erica Liu, J. Bradley Zuchero, Dong Li, Allister F. McGuire, Yuecheng Zhou, Eric Copenhaver, Husniye Kantarci, Yang Yang, Felix S. Alfonso
Publikováno v:
Proc Natl Acad Sci U S A
Understanding how a network of interconnected neurons receives, stores, and processes information in the human brain is one of the outstanding scientific challenges of our time. The ability to reliably detect neuroelectric activities is essential to
Publikováno v:
Organic Letters. 19:2989-2992
We report the exploration into photoredox generation of carbonyl ylides from benzylic epoxides using newly designed 4-mesityl-2,6-diphenylpyrylium tetrafluoroborate (MDPT) and 4-mesityl-2,6-di-p-tolylpyrylium tetrafluoroborate (MD(p-tolyl)PT) catalys
Autor:
Daniel Palanker, Yi Quan, Georges Goetz, Felix S. Alfonso, Tong Ling, Peng Zhou, Tiffany Wanshing Huang, Kevin C. Boyle
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2019.
Wide-field interferometric imaging systems can detect mechanical deformations of a cell during an action potential (AP), such as in quantitative phase microscopy, which is highly sensitive to the changing optical path length. This enables non-invasiv
Autor:
Yi Quan, Tong Ling, Tiffany Wanshing Huang, Daniel Palanker, Peng Zhou, Felix S. Alfonso, Georges Goetz, Kevin C. Boyle
Publikováno v:
Quantitative Phase Imaging V.
Autor:
Daniel Palanker, Georges Goetz, Tong Ling, Felix S. Alfonso, Tiffany Wanshing Huang, Kevin C. Boyle
Publikováno v:
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP).
High-speed quantitative phase microscopy enables full-field imaging of cellular deformations during action potential. In spiking HEK cells, displacements of up to 3nm (0.9mrad) have been observed, and they match the time course electrical recordings.
Autor:
Gulen Yesilbag Tonga, Bo Yan, Vincent M. Rotello, Tsukasa Mizuhara, Singyuk Hou, Patrick W. Fedick, Felix S. Alfonso, Yi-Cheun Yeh, Richard W. Vachet
Publikováno v:
Analytical Chemistry
Synthetic host–guest chemistry is a versatile tool for biomedical applications. Characterization and detection of host–guest complexes in biological systems, however, is challenging due to the complexity of the biological milieu. Here, we describ