Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Felix Royo"'
Autor:
Maria Azparren‐Angulo, Justyna Mleczko, Oihane E. Alboniga, Sergei Kruglik, Jean‐Michel Guigner, Esperanza Gonzalez, Clara Garcia‐Vallicrosa, Jordi Llop, Cristina Simó, Cristina Alonso, Marta Iruarrizaga, Felix Royo, Juan M. Falcon‐Perez
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) have been involved in metabolic syndrome, although their specific role in the development of the pathology is still unknown. To further study the role of EVs, we have analysed by Raman tweezers microspectroscopy
Externí odkaz:
https://doaj.org/article/abd49f41b79c4515bbbe878f208d276b
Three-Dimensional Hepatocyte Spheroids: Model for Assessing Chemotherapy in Hepatocellular Carcinoma
Autor:
Felix Royo, Clara Garcia-Vallicrosa, Maria Azparren-Angulo, Guillermo Bordanaba-Florit, Silvia Lopez-Sarrio, Juan Manuel Falcon-Perez
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1200 (2024)
Background: Three-dimensional cellular models provide a more comprehensive representation of in vivo cell properties, encompassing physiological characteristics and drug susceptibility. Methods: Primary hepatocytes were seeded in ultra-low attachment
Externí odkaz:
https://doaj.org/article/1ec0de80f3f7465abc25c9e62a5810d0
Autor:
Felix Royo, Hector Tames, Guillermo Bordanaba-Florit, Diana Cabrera, Maria Azparren-Angulo, Clara Garcia-Vallicrosa, Abelardo Margolles, Lorena Ruiz, Patricia Ruas-Madiedo, Juan M. Falcon-Perez
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Several studies have described the contribution of glutamate-transforming microbiota to the development of chronic ailments. For instance, the blood concentration of glutamate is higher in some patients with fibromyalgia, chronic fatigue, an
Externí odkaz:
https://doaj.org/article/cac283c25bd4419b9ec669526df0cb91
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15668 (2023)
The human CERS2 gene encodes a ceramide synthase enzyme, known as CERS2 (ceramide synthase 2). This protein is also known as LASS2 (LAG1 longevity assurance homolog 2) and TMSG1 (tumor metastasis-suppressor gene 1). Although previously described as a
Externí odkaz:
https://doaj.org/article/0c88350ec35d4f6380d77da951065958
Autor:
Ana Garcia Garcia de Paredes, Nicolo Manicardi, Luis Tellez, Luis Ibañez, Felix Royo, Javier Bermejo, Carolina Blanco, Constantino Fondevila, Val Fernandez Lanza, Laura Garcia‐Bermejo, Juan Manuel Falcon‐Perez, Rafael Bañares, Jordi Gracia‐Sancho, Agustin Albillos
Publikováno v:
Hepatology Communications, Vol 5, Iss 2, Pp 309-322 (2021)
Noninvasive staging of decompensated cirrhosis is an unmet clinical need. The aims of this study were to characterize and validate a novel microRNA (miRNA) signature to stage decompensated cirrhosis and predict the portal pressure and systolic cardia
Externí odkaz:
https://doaj.org/article/7863e0e5cc364c7fab24c1f1a2833d36
Autor:
Felix Royo, Mikel Azkargorta, Jose L. Lavin, Marc Clos-Garcia, Ana R. Cortazar, Monika Gonzalez-Lopez, Laura Barcena, Hernando A. del Portillo, María Yáñez-Mó, Antonio Marcilla, Francesc E. Borras, Hector Peinado, Isabel Guerrero, Mar Váles-Gómez, Unai Cereijo, Teresa Sardon, Ana M. Aransay, Felix Elortza, Juan M. Falcon-Perez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Extracellular vesicles (EVs) mediate cell-to-cell crosstalk whose content can induce changes in acceptor cells and their microenvironment. MLP29 cells are mouse liver progenitor cells that release EVs loaded with signaling cues that could affect cell
Externí odkaz:
https://doaj.org/article/c4981f88e2b342b0a6d64749d8c47773
Autor:
Felix Royo, David Gil-Carton, Esperanza Gonzalez, Justyna Mleczko, Laura Palomo, Miriam Perez-Cormenzana, Rebeca Mayo, Cristina Alonso, Juan M. Falcon-Perez
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Liver constitutes the major metabolic factory in the organism and is involved in the synthesis, secretion and clearance of many blood-circulating molecules. Previously, we have characterised the protein and RNA cargo of extracellular vesicles (EVs) s
Externí odkaz:
https://doaj.org/article/5e42554878804892b4529ebeedce3e16
Autor:
Mikel Azkargorta, Ibon Iloro, Iraide Escobes, Diana Cabrera, Juan M. Falcon-Perez, Felix Elortza, Felix Royo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11144 (2021)
The proteomic profiling of serum samples supposes a challenge due to the large abundance of a few blood proteins in comparison with other circulating proteins coming from different tissues and cells. Although the sensitivity of protein detection has
Externí odkaz:
https://doaj.org/article/ad4af7b396844502ba0be321555327a0
Autor:
Charles Williams, Felix Royo, Oier Aizpurua-Olaizola, Raquel Pazos, Geert-Jan Boons, Niels-Christian Reichardt, Juan M. Falcon-Perez
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast number of biological processes through intercellular transfer of biomolecules. Increasing research efforts in the EV field have yielded an appreciation for the
Externí odkaz:
https://doaj.org/article/423dd19b73e44d0fa0b14b3fe27d1268
Autor:
Marc Clos-Garcia, Ana Loizaga-Iriarte, Patricia Zuñiga-Garcia, Pilar Sánchez-Mosquera, Ana Rosa Cortazar, Esperanza González, Verónica Torrano, Cristina Alonso, Miriam Pérez-Cormenzana, Aitziber Ugalde-Olano, Isabel Lacasa-Viscasillas, Azucena Castro, Felix Royo, Miguel Unda, Arkaitz Carracedo, Juan M. Falcón-Pérez
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Urine contains extracellular vesicles (EVs) that concentrate molecules and protect them from degradation. Thus, isolation and characterisation of urinary EVs could increase the efficiency of biomarker discovery. We have previously identified proteins
Externí odkaz:
https://doaj.org/article/36e81efc05d64e2f86e84e9dd11ff6c3