Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Felix R. Homberger"'
Publikováno v:
Lab Animal
Housing rodents in IVC racks has many advantages over conventional cages but also presents unique challenges related to health monitoring. The authors review the issues to consider in design of a sentinel program using IVC systems.
Publikováno v:
Laboratory Animals. 33:19-38
Report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Accreditation of Diagnostic Laboratories FELASA Working Group on Accreditation of Diagnostic Laboratories: Felix R. Homberger (Convenor), Ron Boot,
Autor:
Felix R. Homberger, Werner Nicklas, Ivo Kunstyr, Michael Mähler, Herbert Meyer, Karin Jacobi, Gabi Pohlmeyer-Esch, Brunhilde Illgen-Wilcke, Volker Kraft
Publikováno v:
Laboratory Animals. 33:39-87
51:77 Pneumocystis carinii 51:80 Toxoplasma gondii 51:83 Encephalitozoon cuniculi 51:85 Oxyurina 51:87 Mites Introduction It is generally accepted that rodent pathogens may not only be hazardous for animals (and humans) but can severely influence the
Publikováno v:
Proceedings of the Royal Society of London B Biological Sciences, vol. 265, no. 1397, pp. 711-716
In a previous series of in vitro fertilization experiments with mice we found non-random combination of major histocompatibility complex (MHC) haplotypes in the very early embryos. Our results suggested that two selection mechanisms were operating: (
Autor:
Felix R. Homberger
Publikováno v:
Laboratory Animals. 31:97-115
Mouse hepatitis virus (MHV), the coronavirus of the mouse, is the most common viral pathogen in contemporary laboratory mouse colonies throughout the world. It is highly contagious with variable clinical manifestations. The majority of infections are
Publikováno v:
Virology
A strategy for targeted RNA recombination between the spike gene on the genomic RNA of MHV-A59 and a synthetic DI RNA containing the MHV-RI spike gene is described. The MHV-RI spike gene contains several nucleotide differences from the MHV-A59 spike
Publikováno v:
Virus Research
Enterotropic strains of murine coronaviruses (MHV-Y and MHV-RI) differ extensively in their pathogenesis from the prototypic respiratory strains of murine coronaviruses. In an effort to determine which viral proteins might be determinants of enterotr
Autor:
Felix R. Homberger
Publikováno v:
Virus Research
The nucleotide sequences of the membrane (M) protein genes and their deduced amino acid sequences of three enterotropic strains of the coronavirus mouse hepatitis virus (MHV) -Y, -RI and -DVIM were determined and compared with the previously reported
Autor:
Neil S. Lipman, Felix R. Homberger
Publikováno v:
Lab animal. 32(5)
The ability to produce unique strains of genetically engineered mice has revolutionized biomedical research, but has also complicated the maintenance of "clean" facilities through an increase in the movement of animals between facilities and the prod
Publikováno v:
Comparative medicine. 54(4)
The use of individually ventilated caging (IVC) to house mice presents new challenges for effective microbiological monitoring. Methods that exploit the characteristics of IVC have been developed, but to the authors' knowledge, their efficacy has not