Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells.

Autor: Yvonne Lueder, Katrin Heller, Christiane Ritter, Kirsten A Keyser, Karen Wagner, Xiaokun Liu, Martin Messerle, Felix R Stahl, Stephan Halle, Reinhold Förster

Publikováno v: PLoS Pathogens, Vol 14, Iss 8, p e1007252 (2018)

Human cytomegalovirus (CMV) and mouse cytomegalovirus (MCMV) infection share many characteristics. Therefore infection of mice with MCMV is an important tool to understand immune responses and to design vaccines and therapies for patients at the risk

Externí odkaz: https://doaj.org/article/3a6efccf1b404a6fb866e152870d7e7c

Pathogenicity of Human Anti-PLA2R1 Antibodies in Minipigs: A Pilot Study

Autor: Linda Reinhard, Thorsten Wiech, Aline Reitmeier, Moritz Lassé, Maya Machalitza, Asmus Heumann, Nicoletta Ferru, Desiree Loreth, Marie-Luise Schröder, Arvid Hutzfeldt, Felix R. Stahl, Sven Peine, Hermann-Josef Gröne, Catherine Meyer-Schwesinger, Markus M. Rinschen, Rolf A.K. Stahl, Elion Hoxha

Publikováno v: Reinhard, L, Wiech, T, Reitmeier, A, Lassé, M, Machalitza, M, Heumann, A, Ferru, N, Loreth, D, Schröder, M-L, Hutzfeldt, A, Stahl, F R, Peine, S, Gröne, H-J, Meyer-Schwesinger, C, Rinschen, M M, Stahl, R A K & Hoxha, E 2023, ' Pathogenicity of Human anti-PLA2R1 Antibodies in Minipigs : A Pilot Study ', Journal of the American Society of Nephrology : JASN, vol. 34, no. 3, pp. 369-373 . https://doi.org/10.1681/ASN.0000000000000068

BACKGROUND: Primary membranous nephropathy (MN) is an autoimmune kidney disease in which immune complexes are deposited beneath the epithelium in the glomeruli. The condition introduces a high risk for end-stage kidney disease. Seventy to 80 percent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46118a7298788729f30b9fe384761663
https://doi.org/10.1681/asn.0000000000000068

Data from Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model

Autor: Jörg Schrader, Ansgar W. Lohse, Jakob R. Izbicki, Maximillian Bockhorn, Daniel Perez, Corinna Eggers, Martina Fahl, Bence Sipos, Jan Dieckhoff, Markus Möbs, Patricia Grabowski, Martin Anlauf, Felix R. Stahl, Susanne Burdak-Rothkamm, Gerrit Wolters-Eisfeld, Victoria Weissmann, Ludmilla Unrau, Yasmin Behrang, Daniel Benten

Clinical options for systemic therapy of neuroendocrine tumors (NET) are limited. Development of new drugs requires suitable representative in vitro and in vivo model systems. So far, the unavailability of a human model with a well-differentiated phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03c6d542614a5bfff10ae563162a6bfa
https://doi.org/10.1158/1541-7786.c.6541486

Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2

Autor: Luís Fonseca Brito, Silvia Tödter, Julian Kottlau, Kathrin Cermann, Anthea Spier, Elina Petersen, Ines Schäfer, Raphael Twerenbold, Martin Aepfelbacher, Marc Lütgehetmann, Felix R. Stahl

Publikováno v: Frontiers in Immunology. 14

In search for immunological correlates of protection against acute coronavirus disease 2019 (COVID-19) there is a need for high through-put assays for cell-mediated immunity (CMI) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6417d7eac98f6ff0bf44e820ca1cf91
https://doi.org/10.3389/fimmu.2023.1069968

Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy

Autor: Petra C. Arck, Udo R. Markert, Giada Frascaroli, Nadine Felber, Wolfram Brune, Marc Lütgehetmann, Ann Christin Tallarek, Agnes Wieczorek, Kurt Hecher, Stephanie Stanelle-Bertram, Felix R. Stahl, Anke Diemert, Kristin Thiele, Gülsah Gabriel, Christopher Urbschat, Susanne Krasemann, Luis Fonseca Brito

Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

Pregnant women have been carefully observed during the COVID-19 pandemic, as the pregnancy-specific immune adaptation is known to increase the risk for infections. Recent evidence indicates that even though most pregnant have a mild or asymptomatic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dbe0f14f5d12280c838e03228fe520
https://www.frontiersin.org/articles/10.3389/fimmu.2021.698578/full