Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Felix O. Aikhionbare"'
Autor:
Mohan Hei, Xuebiao Yao, Xiao Yuan, Xinjiao Gao, Fangwei Wang, Felix O. Aikhionbare, Divine Mensah Sedzro, Zhen Dou, Ping Gui, Wei Tian, Dongmei Wang, Yihan Yao, Sikai Liu, Najdat Zohbi
Publikováno v:
Journal of Molecular Cell Biology
Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, which is monitored by the spindle assembly checkpoint (SAC) signaling. As an upstream factor of SAC, the precise and dynamic kinetochore localization of Mps1 kinase
Publikováno v:
Tumor Biology. 37:12465-12475
Despite improvements in treatment strategies, colorectal cancer (CRC) still has high mortality rates. Most CRCs develop from adenopolyps via the adenoma-carcinoma sequence. A mechanism for inhibition of this sequence in individuals with a high risk o
Autor:
Zhigang Zheng, Zhen Guo, Xuebiao Yao, Fengsong Wang, Wei Jiang, Felix O. Aikhionbare, Dongmei Wang, Yong Chen, Nerimah Emmett, Donald L. Hill, Ti Zhou, Xing Liu, William W. Yao, Jun Zhao, Dong Liu
Publikováno v:
Journal of Molecular Cell Biology. 8:144-156
Endoplasmic reticulum (ER) stress is involved in ischemic preconditioning that protects various organs from ischemia/reperfusion (I/R) injury. We established an in vivo ER stress preconditioning model in which tunicamycin was injected into rats befor
Publikováno v:
Gastroenterology. 158:S-280
Autor:
LaShanale, Wallace, Anju M, Cherian, Paula, Adamson, Shahla, Bari, Saswati, Banerjee, Michael, Flood, Melvin, Simien, Xuebiao, Yao, Felix O, Aikhionbare
Publikováno v:
Journal of carcinogenesis & mutagenesis
Objective: Colorectal cancer (CRC) develops from precancerous adenomatous polyps to malignant lesions of adenocarcinoma. Elucidating inhibition mechanisms for this route in patients with a risk of developing CRC is highly important for a potential di
Autor:
Melvin Simien, Xuebiao Yao, Anju M Cherian, LaShanale Wallace, Michael Flood, Paula Adamson, Saswati Banerjee, Felix O. Aikhionbare, Shahla Bari
Publikováno v:
Journal of Carcinogenesis & Mutagenesis.
Objective Colorectal cancer (CRC) develops from precancerous adenomatous polyps to malignant lesions of adenocarcinoma. Elucidating inhibition mechanisms for this route in patients with a risk of developing CRC is highly important for a potential dia
Publikováno v:
International journal of clinical medicine
Introduction: Adenopolyps patients have a three-fold higher risk of colon cancer over the general population, which increases to six-fold if the polyps are multiple and with lower survival among African American population. Currently, 6% of CRC can b
Autor:
LaShanale M. Wallace, Aneese F. Chaudhry, Karen I. Aikhionbare, Xuebiao Yao, Felix O. Aikhionbare
Publikováno v:
Cancer Research. 79:1804-1804
Colorectal cancer (CRC) survival rates are stage related and majority of patients (75%) with CRC have sporadic of the disease which is in form of adenoma. Most of colorectal adenocarcinomas precursors are adenomatous polyps. Moreover, CRC appears to
Autor:
Xinjiao Gao, Chuanhai Fu, Changjiang Jin, Fusheng Liu, Felix O. Aikhionbare, Yuwen Ke, Xuebiao Yao, Zhaoyang Wang, Zhen Dou, Zhiyong Wang, Xia Ding, Leilei Xu, Xinghui Wang, Lijuan Zhu, Bo Qin, Tongge Zhu
Publikováno v:
Journal of Biological Chemistry. 288:36149-36159
The spindle assembly checkpoint (SAC) is a quality control device to ensure accurate chromosome attachment to spindle microtubule for equal segregation of sister chromatid. Aurora B is essential for SAC function by sensing chromosome bi-orientation v
Autor:
William E. Grizzle, Felix O. Aikhionbare, Joyce A. Akwe, Xuebiao Yao, Gregory Adams, Sharifeh Mehrabi, Yupha Vatcharapijarn, Osatohamwen I Iyamu
Publikováno v:
Frontiers in Bioscience. :809-813
To investigate the potential role of mtDNA alterations during the onset of colorectal cancer, the occurrence of mtDNA variants in colorectal adenomatous (Tubular, Tubulovillous, and Villous) polyps, were studied. High resolution endonucleases and PCR