Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Felix Meyer"'
Autor:
Marie Vogt, Sandra Classen, Ann Kristin Krause, Nadja-Juanita Peter, Cordula Petersen, Kai Rothkamm, Kerstin Borgmann, Felix Meyer
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 762 (2024)
The ubiquitin specific protease 7 (USP7) is a deubiquitinating enzyme with numerous substrates. Aberrant expression of USP7 is associated with tumor progression. This study aims to investigate how a deregulated USP7 expression affects chromosomal ins
Externí odkaz:
https://doaj.org/article/87a1cedc242645c9bed4b15f52ce9c47
Autor:
Joanna Kempska, Leticia Oliveira-Ferrer, Astrid Grottke, Minyue Qi, Malik Alawi, Felix Meyer, Kerstin Borgmann, Fabienne Hamester, Kathrin Eylmann, Maila Rossberg, Daniel J. Smit, Manfred Jücker, Elena Laakmann, Isabell Witzel, Barbara Schmalfeldt, Volkmar Müller, Karen Legler
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe PI3K/AKT pathway is activated in 43-70% of breast cancer (BC)-patients and promotes the metastatic potential of BC cells by increasing cell proliferation, invasion and radioresistance. Therefore, AKT1-inhibition in combination with ra
Externí odkaz:
https://doaj.org/article/7882ba2141484a4e949b72c38b608411
Autor:
Simon Gehre, Felix Meyer, Azzaya Sengedorj, Fridolin Grottker, Clara M. Reichardt, Jannik Alomo, Kerstin Borgmann, Benjamin Frey, Rainer Fietkau, Michael Rückert, Udo S. Gaipl
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Only a subset of patients with triple-negative breast cancer (TNBC) benefits from a combination of radio- (RT) and immunotherapy. Therefore, we aimed to examine the impact of radioresistance and brain metastasizing potential on the immunological phen
Externí odkaz:
https://doaj.org/article/2c3daa9acc1c4ab1be80ebca2d3caa0b
Autor:
Sabrina Köcher, Henrike Barbara Zech, Leonie Krug, Fruzsina Gatzemeier, Sabrina Christiansen, Felix Meyer, Ruth Rietow, Nina Struve, Wael Yassin Mansour, Malte Kriegs, Cordula Petersen, Christian Betz, Kai Rothkamm, Thorsten Rieckmann
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Patients with human papillomavirus-positive squamous cell carcinoma of the head and neck (HPV+ HNSCC) have a favorable prognosis compared to those with HPV-negative (HPV−) ones. We have shown previously that HPV+ HNSCC cell lines are characterized
Externí odkaz:
https://doaj.org/article/f2c26ea120f9412bb9b27d9776ac1611
Autor:
Felix Meyer, Anna Maria Engel, Ann Kristin Krause, Tim Wagner, Lena Poole, Anna Dubrovska, Claudia Peitzsch, Kai Rothkamm, Cordula Petersen, Kerstin Borgmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cancer stem cells (CSCs) are a major cause of tumor therapy failure. This is mainly attributed to increased DNA repair capacity and immune escape. Recent studies have shown that functional DNA repair via homologous recombination (HR) prevents radiati
Externí odkaz:
https://doaj.org/article/fdb2d8df0fc941a283280939b46c8565
Publikováno v:
European Journal of Cell Biology, Vol 100, Iss 3, Pp 151156- (2021)
Chromosomal instability (CIN) is a hallmark of cancer, resulting from misalignment and missegregation of chromosomes during meta- and anaphase, due to non-precise regulation of spindle-MT dynamics. Diaphanous Related Formin 1 (DIAPH1) is an actin nuc
Externí odkaz:
https://doaj.org/article/1e1eb0cc915b41bca2f1ba3c747de508
Publikováno v:
Applications in Energy and Combustion Science, Vol 5, Iss , Pp 100014- (2021)
In this study, NOx formation in lean premixed burner-stabilized flames was investigated under condensing gas boiler operating conditions for pure methane, methane/propane, and methane/hydrogen mixtures. Temperature and NOx species profiles were exper
Externí odkaz:
https://doaj.org/article/445a18f0cd654563b29c0fb5cf82c859
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Background: There is a lack of studies examining the relationship between osteoporosis and fear of falling as well as the association of osteoporosis and restrictions in daily life due to fear of falling. Thus, the aim of this study was to investigat
Externí odkaz:
https://doaj.org/article/262326e8a68c4ba3b6d516a89848c14c
Autor:
Felix Meyer, Saskia Becker, Sandra Classen, Ann Christin Parplys, Wael Yassin Mansour, Britta Riepen, Sara Timm, Claudia Ruebe, Maria Jasin, Harriet Wikman, Cordula Petersen, Kai Rothkamm, Kerstin Borgmann
Publikováno v:
Cells, Vol 9, Iss 1, p 238 (2020)
Chromosomal instability not only has a negative effect on survival in triple-negative breast cancer, but also on the well treatable subgroup of luminal A tumors. This suggests a general mechanism independent of subtypes. Increased chromosomal instabi
Externí odkaz:
https://doaj.org/article/b53ca6d143a1471da7002a4f957552d2
Long-term memory is essential to feel like a continuous being, and to be able to interact/communicate coherently. Social robots need long-term memories in order to establish long-term relationships with humans and other robots, and do not act just fo
Externí odkaz:
http://arxiv.org/abs/1811.10758