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pro vyhledávání: '"Felix Mertink"'
Autor:
Benedikt Sammet, Christine Weiß, Jens Conradi, Soledad Royo Gracia, Markus Nahrwold, Norbert Sewald, Ralf Palmisano, Felix Mertink, Thomas Preuße, Tobias Bogner
Publikováno v:
Journal of Medicinal Chemistry. 56:1853-1864
Tumor targeting anticancer drug conjugates that contain a tumor recognition motif (homing device) are of high current relevance. Cryptophycins, naturally occurring cytotoxic cyclo-depsipeptides, have been modified by total synthesis to provide analog
Autor:
Felix Mertink, Jens Conradi, Sylwia Huber, Katharina Gaus, Ulf Strijowski, Steffen Backert, Norbert Sewald, Soledad Royo Gracia
Publikováno v:
Amino Acids. 43:219-232
The human pathogen Helicobacter pylori that may cause different gastric diseases exploits integrins for infection of gastric cells. The H. pylori protein CagL present on the outer region of the type IV secretion pilus contains an RGD sequence (-Arg-G