Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Felix M, Key"'
Autor:
Louis L’Hôte, Ian Light, Valeria Mattiangeli, Matthew D. Teasdale, Áine Halpin, Lionel Gourichon, Felix M. Key, Kevin G. Daly
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Brucella melitensis is a major livestock bacterial pathogen and zoonosis, causing disease and infection-related abortions in small ruminants and humans. A considerable burden to animal-based economies today, the presence of Brucella in Neoli
Externí odkaz:
https://doaj.org/article/4c3c0326461d406fbdc3bbff53607eb3
Autor:
Ron Hübler, Felix M. Key, Christina Warinner, Kirsten I. Bos, Johannes Krause, Alexander Herbig
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract High-throughput DNA sequencing enables large-scale metagenomic analyses of complex biological systems. Such analyses are not restricted to present-day samples and can also be applied to molecular data from archaeological remains. Investigati
Externí odkaz:
https://doaj.org/article/9899cf9d60d94a21918d9c2e687cf785
Autor:
Veda D. Khadka, Felix M. Key, Carolina Romo-González, Adrián Martínez-Gayosso, Blanca L. Campos-Cabrera, Armando Gerónimo-Gallegos, Tucker C. Lynn, Carola Durán-McKinster, Rafael Coria-Jiménez, Tami D. Lieberman, Maria T. García-Romero
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
BackgroundAtopic dermatitis (AD) is characterized by an altered skin microbiome dominantly colonized by S. aureus. Standard treatment includes emollients, anti-inflammatory medications and antiseptics.ObjectivesTo characterize changes in the skin mic
Externí odkaz:
https://doaj.org/article/646f682201274696b2382aaab36f352e
Autor:
Xiyan Wu, Chao Ning, Felix M Key, Aida Andrades Valtueña, Aditya Kumar Lankapalli, Shizhu Gao, Xuan Yang, Fan Zhang, Linlin Liu, Zhongzhi Nie, Jian Ma, Johannes Krause, Alexander Herbig, Yinqiu Cui
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009886 (2021)
Salmonella enterica (S. enterica) has infected humans for a long time, but its evolutionary history and geographic spread across Eurasia is still poorly understood. Here, we screened for pathogen DNA in 14 ancient individuals from the Bronze Age Quan
Externí odkaz:
https://doaj.org/article/58b8a48173c245db89297f316e232848
Autor:
Maria A. Spyrou, Marcel Keller, Rezeda I. Tukhbatova, Christiana L. Scheib, Elizabeth A. Nelson, Aida Andrades Valtueña, Gunnar U. Neumann, Don Walker, Amelie Alterauge, Niamh Carty, Craig Cessford, Hermann Fetz, Michaël Gourvennec, Robert Hartle, Michael Henderson, Kristin von Heyking, Sarah A. Inskip, Sacha Kacki, Felix M. Key, Elizabeth L. Knox, Christian Later, Prishita Maheshwari-Aplin, Joris Peters, John E. Robb, Jürgen Schreiber, Toomas Kivisild, Dominique Castex, Sandra Lösch, Michaela Harbeck, Alexander Herbig, Kirsten I. Bos, Johannes Krause
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The second plague pandemic, caused by Yersinia pestis, started in the 14th century and recurred in Europe until the 18th century. Here, the authors reconstruct ancient Y. pestis genomes from human remains spanning this period, shedding light into the
Externí odkaz:
https://doaj.org/article/3862cca408484a71a11606bbdad3d933
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Detecting the targets of positive selection in the human genome is challenging. Here, the authors combine modern and ancient genomes to show that alleles strongly differentiated between Africans and Europeans mediated local adaptation in European pop
Externí odkaz:
https://doaj.org/article/1be2eb237c5f4c1590dc4d4036e3f8cc
Autor:
Felix M Key, Muslihudeen A Abdul-Aziz, Roger Mundry, Benjamin M Peter, Aarthi Sekar, Mauro D'Amato, Megan Y Dennis, Joshua M Schmidt, Aida M Andrés
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007298 (2018)
Ambient temperature is a critical environmental factor for all living organisms. It was likely an important selective force as modern humans recently colonized temperate and cold Eurasian environments. Nevertheless, as of yet we have limited evidence
Externí odkaz:
https://doaj.org/article/9dfb8c5290ce45af85e3f4b1c8a71d22
Autor:
Ben Krause-Kyora, Julian Susat, Felix M Key, Denise Kühnert, Esther Bosse, Alexander Immel, Christoph Rinne, Sabin-Christin Kornell, Diego Yepes, Sören Franzenburg, Henrike O Heyne, Thomas Meier, Sandra Lösch, Harald Meller, Susanne Friederich, Nicole Nicklisch, Kurt W Alt, Stefan Schreiber, Andreas Tholey, Alexander Herbig, Almut Nebel, Johannes Krause
Publikováno v:
eLife, Vol 7 (2018)
The hepatitis B virus (HBV) is one of the most widespread human pathogens known today, yet its origin and evolutionary history are still unclear and controversial. Here, we report the analysis of three ancient HBV genomes recovered from human skeleto
Externí odkaz:
https://doaj.org/article/5d8afae15af841bfbc522b33d6cc248b
Autor:
Aida, Andrades Valtueña, Gunnar U, Neumann, Maria A, Spyrou, Lyazzat, Musralina, Franziska, Aron, Arman, Beisenov, Andrey B, Belinskiy, Kirsten I, Bos, Alexandra, Buzhilova, Matthias, Conrad, Leyla B, Djansugurova, Miroslav, Dobeš, Michal, Ernée, Javier, Fernández-Eraso, Bruno, Frohlich, Mirosław, Furmanek, Agata, Hałuszko, Svend, Hansen, Éadaoin, Harney, Alina N, Hiss, Alexander, Hübner, Felix M, Key, Elmira, Khussainova, Egor, Kitov, Alexandra O, Kitova, Corina, Knipper, Denise, Kühnert, Carles, Lalueza-Fox, Judith, Littleton, Ken, Massy, Alissa, Mittnik, José Antonio, Mujika-Alustiza, Iñigo, Olalde, Luka, Papac, Sandra, Penske, Jaroslav, Peška, Ron, Pinhasi, David, Reich, Sabine, Reinhold, Raphaela, Stahl, Harald, Stäuble, Rezeda I, Tukhbatova, Sergey, Vasilyev, Elizaveta, Veselovskaya, Christina, Warinner, Philipp W, Stockhammer, Wolfgang, Haak, Johannes, Krause, Alexander, Herbig
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(17)
The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout human history, and ancient DNA evidence has shown it afflicted human populations as far back as the Neolithic. Y. pestis genomes recovered from the Eurasian Late Neo
Autor:
Gunnar U. Neumann, Noah Steuri, Luis Roger Esquivel-Gomez, Alexander Herbig, Cosimo Posth, Kirsten I. Bos, Maria A. Spyrou, Marianne Ramstein, Monica Zavattaro, Jessica Beckett, Aleksandr Khokhlov, Philipp W. Stockhammer, Matthias Meyer, Maria Giuseppina Gradoli, Susanna Sabin, Stefania Vai, Ron Hübler, Wolfgang Haak, Alessandro Riga, Johannes Krause, Denise Kühnert, Antje Wissgott, Aditya Kumar Lankapalli, Felix M. Key, Anatoly R. Kantorovich, Yılmaz Selim Erdal, Albert Hafner, David Caramelli, Robin Skeates, Anja Furtwängler, Åshild J. Vågene, Sandra Lösch, Mark Achtman, Rezeda I. Tukhbatova, Marta Burri, Sabine Reinhold, Andrey B. Belinsky, Zhemin Zhou, Sarah Nagel, Vladimir E. Maslov, Svend Hansen, Nabil-Fareed Alikhan, Inga Siebke, Alexey Kalmykov, Andrey A. Chizhevsky
Publikováno v:
Nature ecology & evolution
It has been hypothesized that the Neolithic transition towards an agricultural and pastoralist economy facilitated the emergence of human adapted pathogens. Here, we recovered eight Salmonella enterica subsp. enterica genomes from human skeletons of