Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Felix Lohmann"'
Autor:
Nicolas Mercado, Gabi Schutzius, Christian Kolter, David Estoppey, Sebastian Bergling, Guglielmo Roma, Caroline Gubser Keller, Florian Nigsch, Adrian Salathe, Remi Terranova, John Reece-Hoyes, John Alford, Carsten Russ, Judith Knehr, Dominic Hoepfner, Alexandra Aebi, Heinz Ruffner, Tanner C. Beck, Sajjeev Jagannathan, Calla M. Olson, Hadley E. Sheppard, Selma Z. Elsarrag, Tewis Bouwmeester, Mathias Frederiksen, Felix Lohmann, Charles Y. Lin, Susan Kirkland
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Epidermal homeostasis requires long term stem cell function. Here, the authors apply transcriptional circuitry analysis based on integrated epigenomic profiling of primary human keratinocytes with high and low stem cell function to identify IRF2 as a
Externí odkaz:
https://doaj.org/article/0f22070deb8646359f9b585b7f128992
Autor:
Melusine Bleu, Swann Gaulis, Rui Lopes, Kathleen Sprouffske, Verena Apfel, Sjoerd Holwerda, Marco Pregnolato, Umut Yildiz, Valentina Cordoʹ, Antonella F. M. Dost, Judith Knehr, Walter Carbone, Felix Lohmann, Charles Y. Lin, James E. Bradner, Audrey Kauffmann, Luca Tordella, Guglielmo Roma, Giorgio G. Galli
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Transcription factors are critical regulators of cell identity. Here, the authors use computational and functional genomic approaches to show an oncogenic role of PAX8 in renal cancer. Mechanistic dissection of PAX8 functions reveal its role in activ
Externí odkaz:
https://doaj.org/article/a841cd70bc974e82bf6c4f6bbe42719f
Autor:
Swann Gaulis, Liv Eidsmo, Enrico Ferrero, Piotr Jagiello, Frank Kolbinger, Felix Lohmann, Katharina Bier, Mathias Cardner, Antonio Costanzo, Jaanika Kärner, Curdin Conrad, Lars Iversen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e613a3934c13959b78b37fa1ec88a7
https://doi.org/10.26226/m.62fa009ddcd2c8001911ead5
https://doi.org/10.26226/m.62fa009ddcd2c8001911ead5
Autor:
Pietro Stilli, Simone Bonizzoni, Felix Lohmann-Richters, Luca Beverina, Antonio Papagni, Piercarlo Mustarelli
Publikováno v:
Electrochimica acta 405, 139834-(2022). doi:10.1016/j.electacta.2022.139834
Anionic electrolyzers are expected to play a major role in the future massive production of green hydrogen. In this context, anionic membranes are still a bottleneck for their low conductivity and insufficient long-term chemical stability. In this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa737acb27b104582946cc45406d0ac5
https://juser.fz-juelich.de/record/905932
https://juser.fz-juelich.de/record/905932
Autor:
Stefanie Renz, Tobias Arlt, Nikolay Kardjilov, Lukas Helfen, Cyrille Couture, Alessandro Tengattini, Felix Lohmann-Richters, Werner Lehnert
Publikováno v:
ECS Meeting Abstracts. :1448-1448
Low temperature alkaline water electrolysis is a well-known technology for hydrogen production and advantageous because less noble metals are needed compared to Proton Exchange Membrane (PEM) electrolysis. However, the two-phase flow behavior and esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e746abc41823ba4f74066206c1047066
https://doi.org/10.1149/ma2022-02391448mtgabs
https://doi.org/10.1149/ma2022-02391448mtgabs
Autor:
Carsten Russ, Adrian Salathe, Charles Y. Lin, John Alford, Mathias Frederiksen, Caroline Gubser Keller, Gabi Schutzius, Sajjeev Jagannathan, Sebastian Bergling, Dominic Hoepfner, Heinz Ruffner, Nicolas Mercado, Judith Knehr, Alexandra Aebi, John S. Reece-Hoyes, Guglielmo Roma, David Estoppey, Remi Terranova, Hadley E. Sheppard, Calla M. Olson, Tewis Bouwmeester, Tanner C. Beck, Susan Kirkland, Florian Nigsch, Christian Kolter, Felix Lohmann, Selma Z. Elsarrag
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications
Nature Communications
Resident adult epithelial stem cells maintain tissue homeostasis by balancing self-renewal and differentiation. The stem cell potential of human epidermal keratinocytes is retained in vitro but lost over time suggesting extrinsic and intrinsic regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c9ef08e8616e1ba4a2ab8d68197bb3
http://link.springer.com/article/10.1038/s41467-019-12559-x
http://link.springer.com/article/10.1038/s41467-019-12559-x
Autor:
Judith Knehr, James E. Bradner, Charles Y. Lin, Valentina Cordoʹ, Audrey Kauffmann, Kathleen Sprouffske, Guglielmo Roma, Walter Carbone, Swann Gaulis, Giorgio G. Galli, Antonella F M Dost, Luca Tordella, Rui Lopes, Melusine Bleu, Umut Yildiz, Marco Pregnolato, Felix Lohmann, Verena Apfel, Sjoerd J B Holwerda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications
Transcription factor networks shape the gene expression programs responsible for normal cell identity and pathogenic state. Using Core Regulatory Circuitry analysis (CRC), we identify PAX8 as a candidate oncogene in Renal Cell Carcinoma (RCC) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec6739b6b5497bf507aec40cac2435d
http://link.springer.com/article/10.1038/s41467-019-11672-1
http://link.springer.com/article/10.1038/s41467-019-11672-1
Autor:
Venkatesh Kancherla, Stefan Reinker, Andreas W. Sailer, Dilek Imanci, Guglielmo Roma, Ludivine Challet Meylan, Vanessa Orsini, Tewis Bouwmeester, Lea F. Puehringer, L. Terracciano, Tianliang Sun, Pascal Forcella, Sjoerd J B Holwerda, Jan S. Tchorz, Heinz Ruffner, Monika Pikiolek, Fabian Wu, Sebastian Bergling, Antoine de Weck, Stefano Annunziato, Ulrike Naumann, Elizabeth George, Mevion Oertli, Sven Schuierer, Prisca Liberali, Felix Lohmann, Caibin Sheng, Annick Waldt, Salvatore Piscuoglio, Feng Cong
Publikováno v:
Cell stem cell. 28(10)
AXIN2 and LGR5 mark intestinal stem cells (ISCs) that require WNT/β-Catenin signaling for constant homeostatic proliferation. In contrast, AXIN2/LGR5+ pericentral hepatocytes show low proliferation rates despite a WNT/β-Catenin activity gradient re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4dd8ec47a0b722a1f73e06f912cae0
https://pubmed.ncbi.nlm.nih.gov/34129813
https://pubmed.ncbi.nlm.nih.gov/34129813
Autor:
Gabi Schutzius, Michael Faller, Aimee Reynolds, Ralph Tiedt, Julia Klopp, Florian Fuchs, Laure C. Bouchez, Federico Tortelli, Nelly Leroy, Jonathan J. Turner, Guglielmo Roma, Simona Cotesta, Armin Beyerbach, Peter Drueckes, Shola M Richards, Debora Bonenfant, Heinrich Rueeger, Heinz Ruffner, Jutta Blank, Rémi Terranova, Peter Tarsa, Frederic Grandjean, Florian Nigsch, Sebastian Bergling, Natalie Dales, Alexandra Aebi, Paul W. Manley, Markus Schirle, Christian Kolter, Tewis Bouwmeester, Rene Hemmig, Sukhdeep Sahambi, Lori L. Jennings, Walter Carbone, Felix Lohmann, Alfred Zimmerlin, Jun Li, Susan Kirkland, Steffen Renner, Mathias Frederiksen, Vickie Driver, Amy Berwick, Florence Zink, Jason R. Thomas, Andrea Vaupel, Chris Dimitri, Vito Guagnano, Viktoria Gruber, Malvina Louis, Caroline Gubser Keller, Adrian Salathe
Publikováno v:
Nature chemical biology. 17(3)
Although most acute skin wounds heal rapidly, non-healing skin ulcers represent an increasing and substantial unmet medical need that urgently requires effective therapeutics. Keratinocytes resurface wounds to re-establish the epidermal barrier by tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a8580afdc9f2d099758e215f9da05e
https://pubmed.ncbi.nlm.nih.gov/33462495
https://pubmed.ncbi.nlm.nih.gov/33462495
Association of Ddx5/p68 protein with the upstream erythroid enhancer element (EHS1) of the Klf1 gene
EKLF/KLF1 is an essential transcription factor that plays a global role in erythroid transcriptional activation. It’s own regulation is of interest, as it displays a highly restricted expression pattern, limited to erythroid cells and its progenito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28f8b64384016dcf8cd388c645ef9f6