Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Felix Knab"'
Autor:
Philipp Euskirchen, Josefine Radke, Marc Sören Schmidt, Eva Schulze Heuling, Eric Kadikowski, Meron Maricos, Felix Knab, Ulrike Grittner, Norman Zerbe, Marcus Czabanka, Christoph Dieterich, Hrvoje Miletic, Sverre Mørk, Arend Koch, Matthias Endres, Christoph Harms
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185376 (2017)
The transcription factor ZEB1 has gained attention in tumor biology of epithelial cancers because of its function in epithelial-mesenchymal transition, DNA repair, stem cell biology and tumor-induced immunosuppression, but its role in gliomas with re
Externí odkaz:
https://doaj.org/article/4a26f70bd2cc4bdf96673d099e92441c
Autor:
Philipp Euskirchen, Christoph Harms, Roel G. Verhaak, Christoph Dieterich, Marcus Czabanka, Arend Koch, Emmanuel Martinez-Ledesma, Eskil Eskilsson, Josefine Radke, Felix Knab, Eva Schulze Heuling
Tumor purity of matched tumor/cell line pairs: Tumor purity of GBM bulk tumor samples and matched gliomasphere cell lines was determined either using ESTIMATE for deconvolution of gene expression profiles (A) or pTERT MAF (B, C). Connected dots indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ae4415f3eef7e8cb2bd7a33ea8c02d
https://doi.org/10.1158/1541-7786.22511335
https://doi.org/10.1158/1541-7786.22511335
Data from Prognostic Relevance of Tumor Purity and Interaction with MGMT Methylation in Glioblastoma
Autor:
Philipp Euskirchen, Christoph Harms, Roel G. Verhaak, Christoph Dieterich, Marcus Czabanka, Arend Koch, Emmanuel Martinez-Ledesma, Eskil Eskilsson, Josefine Radke, Felix Knab, Eva Schulze Heuling
Promoter methylation status of O-6-methylguanine-DNA methyltransferase (MGMT), a DNA repair enzyme, is a critical biomarker in glioblastoma (GBM), as treatment decisions and clinical trial inclusion rely on its accurate assessment. However, interpret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec049f9bdfa9d0f0938ef5841c93a5db
https://doi.org/10.1158/1541-7786.c.6539914.v1
https://doi.org/10.1158/1541-7786.c.6539914.v1
Autor:
Philipp Euskirchen, Christoph Harms, Roel G. Verhaak, Christoph Dieterich, Marcus Czabanka, Arend Koch, Emmanuel Martinez-Ledesma, Eskil Eskilsson, Josefine Radke, Felix Knab, Eva Schulze Heuling
Primers and annealing temperatures used in quantitative allele-specific real-time PCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfcab1006a0a5b419d5835395a6a772
https://doi.org/10.1158/1541-7786.22511326.v1
https://doi.org/10.1158/1541-7786.22511326.v1
Autor:
Philipp Euskirchen, Christoph Harms, Roel G. Verhaak, Christoph Dieterich, Marcus Czabanka, Arend Koch, Emmanuel Martinez-Ledesma, Eskil Eskilsson, Josefine Radke, Felix Knab, Eva Schulze Heuling
Telomerase promoter genotype and MGMT status in matched glioblastoma tumor vs. cell line pairs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6686bedcf14ca9a676349dc6d3e7ed9c
https://doi.org/10.1158/1541-7786.22511329.v1
https://doi.org/10.1158/1541-7786.22511329.v1
Autor:
Felix Knab, Stefan Paul Koch, Sebastian Major, Tracy D. Farr, Susanne Mueller, Philipp Euskirchen, Moritz Eggers, Melanie T.C. Kuffner, Josefine Walter, Daniel Berchtold, Samuel Knauss, Jens P. Dreier, Andreas Meisel, Matthias Endres, Ulrich Dirnagl, Nikolaus Wenger, Christian J. Hoffmann, Philipp Boehm-Sturm, Christoph Harms
BackgroundPrediction of post-stroke outcome using the degree of subacute deficit or magnetic resonance imaging is well studied in humans. While mice are frequently used animals in preclinical stroke research, systematic analysis of outcome predictors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a042de7a1d1d53688f621b3ded457e4
https://doi.org/10.1101/2022.05.13.491869
https://doi.org/10.1101/2022.05.13.491869
Autor:
Christoph Harms, Felix Knab, Philipp Euskirchen, Christoph Dieterich, Marcus Czabanka, Emmanuel Martinez-Ledesma, Roel G.W. Verhaak, Arend Koch, Josefine Radke, Eva Schulze Heuling, Eskil Eskilsson
Publikováno v:
Molecular Cancer Research. 15:532-540
Promoter methylation status of O-6-methylguanine-DNA methyltransferase (MGMT), a DNA repair enzyme, is a critical biomarker in glioblastoma (GBM), as treatment decisions and clinical trial inclusion rely on its accurate assessment. However, interpret
Autor:
Stefan Koch, Susanne Mueller, Marco Foddis, Dominik von Elverfeldt, Thomas Bienert, André Rex, Monika Dopatka, Tracy D. Farr, Ulrich Dirnagl, René Bernard, Philipp Boehm-Sturm, Felix Knab, Christoph Harms
Publikováno v:
Journal of cerebral blood flow & metabolism 39(2), 313-323 (2017). doi:10.1177/0271678X17726635
Journal of Cerebral Blood Flow & Metabolism
Journal of Cerebral Blood Flow & Metabolism
Lesion volume measurements with magnetic resonance imaging are widely used to assess outcome in rodent models of stroke. In this study, we improved a mathematical framework to correct lesion size for edema which is based on manual delineation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff864c3dabce2a137a5312729f72baf
https://pub.dzne.de/record/140464
https://pub.dzne.de/record/140464
Autor:
Eva Schulze Heuling, Marc Soeren Schmidt, Matthias Endres, Arend Koch, Christoph Harms, Philipp Euskirchen, Christoph Dieterich, Marcus Czabanka, Sverre Mørk, Norman Zerbe, Meron Maricos, Ulrike Grittner, Eric Kadikowski, Felix Knab, Josefine Radke, Hrvoje Miletic
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0185376 (2017)
PLOS ONE 12(9), e0185376 (2017). doi:10.1371/journal.pone.0185376
PLoS ONE, Vol 12, Iss 9, p e0185376 (2017)
PLOS ONE 12(9), e0185376 (2017). doi:10.1371/journal.pone.0185376
The transcription factor ZEB1 has gained attention in tumor biology of epithelial cancers because of its function in epithelial-mesenchymal transition, DNA repair, stem cell biology and tumor-induced immunosuppression, but its role in gliomas with re
Autor:
Hrvoje Miletic, Philipp Euskirchen, Matthias Endres, Eric Kadikowski, Ulrike Grittner, Felix Knab, Jun Cheng, Josefine Radke, Norman Zerbe, Marc Sören Schmidt, Eva Schulze Heuling, Sverre Mørk, Arend Koch, Meron Maricos, Christoph Dieterich, Marcus Czabanka, Christoph Harms
Publikováno v:
Neuro-Oncology. 17:v139.3-v139
OBJECTIVE: The transcription factor ZEB1 has gained attention in tumor biology of epithelial cancers because of its suggested roles in epithelial-mesenchymal transition, DNA repair, mediation of stem cell properties and tumor-induced immunosuppressio