Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Felix Kannapin"'
Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells
Autor:
Natalie Burkard, Michael Meir, Felix Kannapin, Christoph Otto, Maximilian Petzke, Christoph-Thomas Germer, Jens Waschke, Nicolas Schlegel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to changes of tight junctions (TJ) leading to impaired intestinal epithelial barrier (IEB) function by undefined mechanisms. We characterized the interplay
Externí odkaz:
https://doaj.org/article/1098f45c6ba440338f7f3a796c17e094
Autor:
Michael Meir, Felix Kannapin, Markus Diefenbacher, Yalda Ghoreishi, Catherine Kollmann, Sven Flemming, Christoph-Thomas Germer, Jens Waschke, Patrick Leven, Reiner Schneider, Sven Wehner, Natalie Burkard, Nicolas Schlegel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1887 (2021)
Enteric glial cells (EGCs) of the enteric nervous system are critically involved in the maintenance of intestinal epithelial barrier function (IEB). The underlying mechanisms remain undefined. Glial cell line-derived neurotrophic factor (GDNF) contri
Externí odkaz:
https://doaj.org/article/fdf3e528943d4efd961a78c7af8af870
Autor:
Felix, Kannapin1 (AUTHOR), Tobias, Schmitz2 (AUTHOR), Jan, Hansmann2,3 (AUTHOR), Nicolas, Schlegel1 (AUTHOR), Michael, Meir1 (AUTHOR) Meir_M@ukw.de
Publikováno v:
Histochemistry & Cell Biology. Dec2021, Vol. 156 Issue 6, p609-616. 8p.
Autor:
Natalie Burkard, Michael Meir, Felix Kannapin, Christoph Otto, Maximilian Petzke, Christoph‐Thomas Germer, Jens Waschke, Nicolas Schlegel
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Histochemistry and Cell Biology. 157:119-119
Autor:
Christina Fey, Felix Kannapin, Christoph-Thomas Germer, Christopher Beck, Catherine Kollmann, Jonas Salm, Jens Waschke, Natalie Burkard, Marco Metzger, Michael Meir, Nicolas Schlegel, Matthias Schweinlin
Publikováno v:
Journal of Crohn'scolitis. 14(10)
BackgroundThe mechanisms underlying loss of intestinal epithelial barrier [IEB] function in Crohn’s disease [CD] are poorly understood. We tested whether human enteroids generated from isolated intestinal crypts of CD patients serve as an appropria
Autor:
Sven Flemming, Jens Waschke, Hanna Ungewiß, Felix Kannapin, Marco Metzger, Michael Meir, Nicolas Schlegel, Matthias Schweinlin, Christoph-Thomas Germer, Markus E. Diefenbacher, Natalie Burkard
Publikováno v:
The Journal of clinical investigation. 129(7)
Impaired intestinal epithelial barrier (IEB) function with loss of desmosomal junctional protein desmoglein 2 (DSG2) is a hallmark in the pathogenesis of inflammatory bowel disease (IBD). While previous studies have reported that glial cell line-deri