Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Felix Kühnl"'
Publikováno v:
BMC Bioinformatics, Vol 18, Iss S12, Pp 47-55 (2017)
Abstract Background The binding of small ligands to RNA elements can cause substantial changes in the RNA structure. This constitutes an important, fast-acting mechanism of ligand-controlled transcriptional and translational gene regulation implement
Externí odkaz:
https://doaj.org/article/b4087bfadbca48058239c2e57587b53c
Autor:
Christopher Klapproth, Siegfried Zöztsche, Felix Kühnl, Jörg Fallmann, Peter F. Stadler, Sven Findeiß
The in silico prediction of non-coding and protein-coding genetic loci is an area of research that has gathered large attention in the field of comparative genomics. In the last decade, much effort has been made to investigate numerous properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef900a99754055c056dad55de1e4105
https://doi.org/10.1101/2022.09.01.506220
https://doi.org/10.1101/2022.09.01.506220
Autor:
Peter F. Stadler, Katharina Arnold, Mario Mörl, Sven Findeiß, Christian Günzel, Christina E Weinberg, Felix Kühnl
Publikováno v:
RNA Biol
Gene regulation in prokaryotes often depends on RNA elements such as riboswitches or RNA thermometers located in the 5’ untranslated region of mRNA. Rearrangements of the RNA structure in response, e. g., to the binding of small molecules or ions c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28264085eedcaed79ed3c13160de4535
https://doi.org/10.1101/2020.06.18.159046
https://doi.org/10.1101/2020.06.18.159046
Autor:
Lukas Wehlte, Julia Walter, Lea Daisenberger, Felix Kuhnle, Maria Ingenerf, Christine Schmid-Tannwald, Matthias Brendel, Diego Kauffmann-Guerrero, Lucie Heinzerling, Amanda Tufman, Thomas Pfluger, Friederike Völter
Publikováno v:
Diagnostics, Vol 14, Iss 11, p 1139 (2024)
Background: A debate persists on the prognostic value of the pre-therapeutic standardized uptake value (SUV) of non-tumorous lung tissue for the risk assessment of therapy-related pneumonitis, with most studies lacking significant correlation. Howeve
Externí odkaz:
https://doaj.org/article/b5762d8df97f407c91d6c5083b1b3595
Autor:
Felix Kühnl, Michael T. Wolfinger, Ivo L. Hofacker, Sven Findeiß, Stefan Hammer, Christoph Flamm
Publikováno v:
Methods (San Diego, Calif.). 143
This contribution sketches a work flow to design an RNA switch that is able to adapt two structural conformations in a ligand-dependent way. A well characterized RNA aptamer, i. e., knowing its Kd and adaptive structural features, is an essential ing