Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Felix Hohendanner"'
Autor:
Felix Hohendanner, Markus Boegner, Judith Huettemeister, Kun Zhang, Stephan Dreysse, Christoph Knosalla, Volkmar Falk, Felix Schoenrath, Isabell Anna Just, Philipp Stawowy
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303540 (2024)
IntroductionMicrovascular dysfunction (MVD) is a hallmark feature of chronic graft dysfunction in patients that underwent orthotopic heart transplantation (OHT) and is the main contributor to impaired long-term graft survival. The aim of this study w
Externí odkaz:
https://doaj.org/article/945c8b00981a405299d0d1e975223b5b
Autor:
Felix Hohendanner, Matthias Bock, Julian Keznickl-Pulst, Vesna Furundzija, Sebastian Scholz, Doreen Schöppenthau, Yuriy Hrytsyna, Volkmar Falk, Burkert Pieske, Gerhard Hindricks, Evgenij Potapov, Jin-Hong Gerds-Li
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Aims: Left-ventricular-assist-devices (lvad) are an established treatment for patients with severe heart failure with reduced ejection fraction (HF) and reduce mortality. However, HF patients have significant substrate for ventricular tachycardia (VT
Externí odkaz:
https://doaj.org/article/74717b052669462fa2733ee6fd9af34b
Autor:
Florian Blaschke, Philipp Lacour, Phi Long Dang, Abdul Shokor Parwani, Felix Hohendanner, Thula Walter, Karin Klingel, Uwe Kühl, Frank R. Heinzel, Mohammad Sherif, Leif‐Hendrik Boldt, Burkert Pieske, Carsten Tschöpe
Publikováno v:
ESC Heart Failure, Vol 8, Iss 4, Pp 2591-2596 (2021)
Abstract Aim Wearable cardioverter defibrillator (WCD, LifeVest, and Zoll) therapy has become a useful tool to bridge a temporarily increased risk for sudden cardiac death. However, despite extensive use, there is a lack of evidence whether patients
Externí odkaz:
https://doaj.org/article/000d00cf34574d209370a84190123ecb
Autor:
Niklas Hegemann, Uwe Primessnig, David Bode, Paulina Wakula, Nicola Beindorff, Robert Klopfleisch, Laura Michalick, Jana Grune, Felix Hohendanner, Daniel Messroghli, Burkert Pieske, Wolfgang M. Kuebler, Frank R. Heinzel
Publikováno v:
ESC Heart Failure, Vol 8, Iss 4, Pp 3130-3144 (2021)
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is frequently (30%) associated with right ventricular (RV) dysfunction, which increases morbidity and mortality in these patients. Yet cellular mechanisms of RV remodelling and RV d
Externí odkaz:
https://doaj.org/article/dff40617184144adbb4ba44a3bd6fdd6
Autor:
David Bode, Natale P.L. Rolim, Tim Guthof, Niklas Hegemann, Paulina Wakula, Uwe Primessnig, Anne Marie Ormbostad Berre, Volker Adams, Ulrik Wisløff, Burkert M. Pieske, Frank R. Heinzel, Felix Hohendanner, OptimEx Study Group
Publikováno v:
ESC Heart Failure, Vol 8, Iss 3, Pp 1806-1818 (2021)
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent disease. Physical exercise has been shown to alter disease progression in HFpEF. We examined cardiomyocyte Ca2+ homeostasis and left ventricular functio
Externí odkaz:
https://doaj.org/article/6a6849dc93004a30b0f9edca5a9d6815
Autor:
Uwe Primessnig, Peter M. Deißler, Paulina Wakula, Khai Liem Tran, Felix Hohendanner, Dirk von Lewinski, Florian Blaschke, Christoph Knosalla, Volkmar Falk, Burkert Pieske, Herko Grubitzsch, Frank R. Heinzel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundAlthough the angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril/valsartan started a new era in heart failure (HF) treatment, less is known about the tissue-level effects of the drug on the atrial myocardial functional reserve and a
Externí odkaz:
https://doaj.org/article/3ab69dbeaf1246f5a94ad8f0519b684f
Autor:
Felix Hohendanner, Ashok Prabhu, Nicola Wilck, Verena Stangl, Burkert Pieske, Karl Stangl, Till F. Althoff
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 526 (2023)
Background: Atrial fibrillation (AF) is promoted by various stimuli like angiotensin II, endothelin-1, epinephrine/norepinephrine, vagal activation, or mechanical stress, all of which activate receptors coupled to G-proteins of the Gαq/Gα11-family
Externí odkaz:
https://doaj.org/article/96a903d49b1b46918e50d6e65bccffb3
Autor:
David Bode, Lukas Semmler, Paulina Wakula, Niklas Hegemann, Uwe Primessnig, Nicola Beindorff, David Powell, Raphael Dahmen, Hartmut Ruetten, Christian Oeing, Alessio Alogna, Daniel Messroghli, Burkert M. Pieske, Frank R. Heinzel, Felix Hohendanner
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Sodium–glucose linked transporter type 2 (SGLT-2) inhibition has been shown to reduce cardiovascular mortality in heart failure independently of glycemic control and prevents the onset of atrial arrhythmias, a common co-morbidit
Externí odkaz:
https://doaj.org/article/57d4817c45a544b8a94b775a2cf0aec3
Autor:
Philipp Lacour, Phi Long Dang, Daniel Armando Morris, Abdul Shokor Parwani, Wolfram Doehner, Franziska Schuessler, Felix Hohendanner, Frank R. Heinzel, Andrea Stroux, Carsten Tschoepe, Wilhelm Haverkamp, Leif‐Hendrik Boldt, Burkert Pieske, Florian Blaschke
Publikováno v:
ESC Heart Failure, Vol 7, Iss 3, Pp 1072-1084 (2020)
Abstract Aims Cardiac resynchronization therapy (CRT) improves functional status, induces reverse left ventricular remodelling, and reduces hospitalization and mortality in patients with symptomatic heart failure, left ventricular systolic dysfunctio
Externí odkaz:
https://doaj.org/article/4131d89ce4b9477a841eb24c3e453b99
Autor:
Sanzio Dimai, Lukas Semmler, Ashok Prabhu, Harald Stachelscheid, Judith Huettemeister, Sandra C Klaucke, Philipp Lacour, Florian Blaschke, Jan Kruse, Abdul Parwani, Leif-Hendrik Boldt, Lars Bullinger, Burkert M Pieske, Frank R Heinzel, Felix Hohendanner
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255976 (2021)
BackgroundCardiac injury associated with cytokine release frequently occurs in SARS-CoV-2 mediated coronavirus disease (COVID19) and mortality is particularly high in these patients. The mechanistic role of the COVID19 associated cytokine-storm for t
Externí odkaz:
https://doaj.org/article/4476b492c64a4699850bcb2fb41fa471