Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Felix Haglund"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 960-965 (2024)
Introduction: Here, we report the first case of a soft tissue tumor with a PAK2::RAF1 fusion. Case Presentation: The patient was an 11-year-old female presenting with a 5 cm intramuscular mass in the lower leg. Microscopic examination revealed a mito
Externí odkaz:
https://doaj.org/article/8d7af6e1416242ea86eac67814fc0438
Autor:
Le Tong, Veronika Kremer, Shi Yong Neo, Yaxuan Liu, Yi Chen, Arnika Kathleen Wagner, Ying Yang, Ziqing Chen, Christina Seitz, Nicholas Patrick Tobin, Maarten Alexander Ligtenberg, Evren Alici, Xinsong Chen, Felix Haglund, Barbara Seliger, Ulrika Harmenberg, Eugenia Colón, Ann‐Helén Scherman Plogell, Lisa Lei Liu, Andreas Lundqvist
Publikováno v:
Cancer Communications, Vol 43, Iss 7, Pp 855-859 (2023)
Externí odkaz:
https://doaj.org/article/f754139632394b4abbaab496545dde86
Autor:
Demi Brownlie, Andreas von Kries, Giampiero Valenzano, Nicole Wild, Emel Yilmaz, Jesper Säfholm, Mamdoh Al-Ameri, Evren Alici, Hans-Gustaf Ljunggren, Igor Schliemann, Ozan Aricak, Felix Haglund de Flon, Jakob Michaëlsson, Nicole Marquardt
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTLung cancer is a leading cause of cancer-related death worldwide. Despite recent advances in tissue immunology, little is known about the spatial distribution of tissue-resident lymphocyte subsets in lung tumors. Using high-parameter flow cyt
Externí odkaz:
https://doaj.org/article/000ae8fd19714447920bbd41b44f02c9
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2729-2734 (2022)
Abstract Background Gastrointestinal stromal tumors (GIST) are mesenchymal tumors in the intestinal tract originating from a precursor to the interstitial cells of Cajal, which plays a role in gastric motility. The preoperative diagnosis of GIST may
Externí odkaz:
https://doaj.org/article/40cae2d61fc54050a47ebdbb941fce11
Autor:
Andreas Lundqvist, Felix Haglund, Johan Hartman, Björn Önfelt, Apple Hui Min Tay, Rubén Prieto-Díaz, Shiyong Neo, Le Tong, Xinsong Chen, Valentina Carannante, Maria Majellaro, Jhonny Azuaje, Xerardo Garcia-Mera, Jose M Brea, Maria I Loza, Willem Jespers, Hugo Gutierrez-de-Teran, Eddy Sotelo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)
Background Adenosine is a metabolite that suppresses antitumor immune response of T and NK cells via extracellular binding to the two subtypes of adenosine-2 receptors, A2ARs. While blockade of the A2AARs subtype effectively rescues lymphocyte activi
Externí odkaz:
https://doaj.org/article/459b1040db484d5f931d73069318670c
Autor:
Yi Chen, Shuwen You, Jie Li, Yifan Zhang, Georgia Kokaraki, Elisabeth Epstein, Joseph Carlson, Wen-Kuan Huang, Felix Haglund
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Despite the fact that management of EC is moving towards four TCGA-based molecular classifications, a pronounced variation in immune response among these molecular subtypes limits its clinical use. We aimed to investigate the determinant biomarker of
Externí odkaz:
https://doaj.org/article/15ed4b84347b480192fae39105400591
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundCancer immunotherapy has produced significant positive clinical effects in a variety of tumor types. However, pancreatic ductal adenocarcinoma (PDAC) is widely considered to be a “cold” cancer with poor immunogenicity. Our aim is to det
Externí odkaz:
https://doaj.org/article/f2fae199872a46a487a2df966b8518a7
Autor:
Yi Chen, Asle C. Hesla, Yingbo Lin, Mehran Ghaderi, Mingzhi Liu, Chen Yang, Yifan Zhang, Panagiotis Tsagkozis, Olle Larsson, Felix Haglund
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1101-1117 (2020)
Ewing sarcomas (ESs) are aggressive sarcomas driven by EWS fusion genes. We sought to investigate whether whole‐transcriptome sequencing (RNA‐seq) could be used to detect patterns associated with chemotherapy response or tumor progression after f
Externí odkaz:
https://doaj.org/article/fa8a9c3d63ef4c5c8c8c7eb770313be1
Publikováno v:
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-7 (2020)
Abstract Background Metastatic neuroendocrine carcinoma often presents as carcinoma of unknown primary. Although most cases display immunohistochemical positivity for neuroendocrine markers, subsets of cases display reduced or negative expression for
Externí odkaz:
https://doaj.org/article/13e01a9e535d45dcb6f29415473463a7
Autor:
Yifan Zhang, Yi Chen, Andri Papakonstantinou, Panagiotis Tsagkozis, Christina Linder-Stragliotto, Felix Haglund
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 292 (2022)
Immune checkpoint inhibitors (ICIs) such as PD1/PD-L1 blockers are an established treatment for many solid cancers. There are currently no approved ICIs for sarcomas, but satisfactory results have been seen in some patients with disseminated disease
Externí odkaz:
https://doaj.org/article/5d63ac4b1b8f410f9492040e3a776b40