Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Felix Häberlein"'
Autor:
Christina Wilms, Klaudia Lepka, Felix Häberlein, Steven Edwards, Jörg Felsberg, Linda Pudelko, Tobias T. Lindenberg, Gereon Poschmann, Nan Qin, Katrin Volbracht, Tim Prozorovski, Sven G. Meuth, Ulf D. Kahlert, Marc Remke, Orhan Aktas, Guido Reifenberger, Lars Bräutigam, Benjamin Odermatt, Carsten Berndt
Publikováno v:
Redox Biology, Vol 49, Iss , Pp 102221- (2022)
Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here, we demonstrate that the cytosolic isoform of the vertebrate-specific oxidoreductase Glutare
Externí odkaz:
https://doaj.org/article/2e1d65566877484caf8912ee69a75699
Autor:
Hendrik Bussmann, Janka Schulte-Michels, Mara Bingel, Fabio Meurer, Stefan Aatz, Felix Häberlein, Sebastian Franken, Hanns Häberlein
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e03960- (2020)
The β2-adrenergic receptor (β2AR) is relevant for surfactant formation in alveolar type 2 cells and reduction of intracellular calcium concentration in bronchial muscle cells and thus for secretolytic and bronchospasmolytic effects. Herbal medicina
Externí odkaz:
https://doaj.org/article/7310d78265c74fb38b77d0000fe7bfeb
Autor:
Katrin M. Krebs, Eva M. Pfeil, Katharina Simon, Manuel Grundmann, Felix Häberlein, Oscar M. Bautista-Aguilera, Michael Gütschow, C. David Weaver, Bernd K. Fleischmann, Evi Kostenis
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14814-14823 (2018)
Externí odkaz:
https://doaj.org/article/cf66ec141f544b888b152e97640163db
Autor:
Felix Häberlein, Enrico Mingardo, Nicole Merten, Nina-Katharina Schulze Köhling, Philip Reinoß, Katharina Simon, Anna Japp, Bhuvaneswari Nagarajan, Ramona Schrage, Cecile Pegurier, Michel Gillard, Kelly R. Monk, Benjamin Odermatt, Evi Kostenis, Jesus Gomeza
Publikováno v:
Cell chemical biology. 29(10)
Therapies that promote neuroprotection and axonal survival by enhancing myelin regeneration are an unmet need to prevent disability progression in multiple sclerosis. Numerous potentially beneficial compounds have originated from phenotypic screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9ed5fc452ac2b4b0d8ed46423da85e
https://pubmed.ncbi.nlm.nih.gov/36270232
https://pubmed.ncbi.nlm.nih.gov/36270232
Autor:
Andrea Christ, Öznur Yilmaz, Roger Sandhoff, Henning Kleinert, Birgit Rau, Benjamin Odermatt, Britta Eiberger, Matthias Eckhardt, Anna Sophia Japp, Alexander Harder, Felix Häberlein, Angelika Zoons, Ulrich Kubitscheck, Bhuvaneswari Nagarajan, Dieter Hartmann, Enrico Mingardo
Publikováno v:
Glia. 68:509-527
In contrast to humans and other mammals, zebrafish can successfully regenerate and remyelinate central nervous system (CNS) axons following injury. In addition to common myelin proteins found in mammalian myelin, 36K protein is a major component of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a835468599c88bdaa69f5201f783d36
https://doi.org/10.1002/glia.23732
https://doi.org/10.1002/glia.23732
Autor:
Michael Gütschow, Eva Marie Pfeil, Katharina Simon, Manuel Grundmann, Oscar M Bautista-Aguilera, C. David Weaver, Felix Häberlein, Katrin M Krebs, Evi Kostenis, Bernd K. Fleischmann
Publikováno v:
ACS Omega
ACS Omega, Vol 3, Iss 11, Pp 14814-14823 (2018)
ACS Omega, Vol 3, Iss 11, Pp 14814-14823 (2018)
Dynamic mass redistribution (DMR) and cellular dielectric spectroscopy (CDS) are label-free biosensor technologies that capture real-time integrated cellular responses upon exposure to extra- and intracellular stimuli. They register signaling routes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dae0fb6ee7eee303c5fb0eda41c323a
http://europepmc.org/articles/PMC6289404
http://europepmc.org/articles/PMC6289404
Autor:
Junken Aoki, Evi Kostenis, Daniela Wenzel, Nicole Merten, Nina Heycke, Maddalena Vescovo, Bernd K. Fleischmann, Ina Maria Albrecht, Katharina Simon, Alexander Pfeifer, Michaela Matthey, Gabriele M. König, Stephanie Hennen, Francois Marie Ngako Kadji, Felix Häberlein, Bernhard Nieswandt, Timo Vögtle, Kouki Kawakami, Julian Brands, Suzune Hiratsuka, Jaspal Garg, Asuka Inoue, Eva Marie Pfeil, Akos Heinemann, Marie Lise Jobin, Yuki Ono, Kerstin Seier, Davide Calebiro, Ulrike Rick
Mechanisms that control mobilization of cytosolic calcium [Ca2+]i are key for regulation of numerous eukaryotic cell functions. One such paradigmatic mechanism involves activation of phospholipase Cβ (PLCβ) enzymes by G protein βγ subunits from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67b365bfcd1d76a4cd31c504e9faee2
http://hdl.handle.net/11390/1205646
http://hdl.handle.net/11390/1205646
Autor:
Suvi, Annala, Xiaodong, Feng, Naveen, Shridhar, Funda, Eryilmaz, Julian, Patt, JuHee, Yang, Eva M, Pfeil, Rodolfo Daniel, Cervantes-Villagrana, Asuka, Inoue, Felix, Häberlein, Tanja, Slodczyk, Raphael, Reher, Stefan, Kehraus, Stefania, Monteleone, Ramona, Schrage, Nina, Heycke, Ulrike, Rick, Sandra, Engel, Alexander, Pfeifer, Peter, Kolb, Gabriele, König, Moritz, Bünemann, Thomas, Tüting, José, Vázquez-Prado, J Silvio, Gutkind, Evelyn, Gaffal, Evi, Kostenis
Publikováno v:
Science signaling. 12(573)
Somatic gain-of-function mutations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bffa928cc1ba9c41db58509ea2791eca
https://pubmed.ncbi.nlm.nih.gov/30890659
https://pubmed.ncbi.nlm.nih.gov/30890659
Autor:
Xiaodong Feng, Stefania Monteleone, Felix Häberlein, Julian Patt, José Vázquez-Prado, Ramona Schrage, Funda Eryilmaz, Gabriele M. König, Moritz Bünemann, Asuka Inoue, Evelyna Gaffal, Sandra Engel, Tanja Slodczyk, Naveen Shridhar, Peter Kolb, J. Silvio Gutkind, Nina Heycke, Ulrike Rick, Evi Kostenis, Ju Hee Yang, Suvi Annala, Eva Marie Pfeil, Stefan Kehraus, Raphael Reher, Rodolfo Daniel Cervantes-Villagrana, Alexander Pfeifer, Thomas Tüting
Publikováno v:
Science Signaling. 12
Somatic gain-of-function mutations of GNAQ and GNA11, which encode α subunits of heterotrimeric Gαq/11 proteins, occur in about 85% of cases of uveal melanoma (UM), the most common cancer of the adult eye. Molecular therapies to directly target the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5181b7d3d2f3064a199ecc3e58308bec
https://doi.org/10.1126/scisignal.aau5948
https://doi.org/10.1126/scisignal.aau5948
Autor:
Manuel Martinez-Osuna, Katharina Engelhard, Hanns Häberlein, Anne Sieben, Felix Häberlein, Janka Schulte-Michels, Stefan Aatz, Anne Wolf
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 23(1)
Background Recently is has been shown that α- and β-hederin increase the β 2 -adrenergic responsiveness of alveolar type II cells (A549) and human airway smooth muscle cells (HASM), respectively, by inhibiting the internalization of β 2 -adrenerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ec65ce1f884b33ce9537d3f023f31c
https://pubmed.ncbi.nlm.nih.gov/26902407
https://pubmed.ncbi.nlm.nih.gov/26902407