Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Felix Gnerlich"'
Autor:
Julie Weidner, Ewa Kolosionek, Reetta Holmila, Elisabeth Ax, Marion Garreau, Felix Gnerlich, Henric Olsson, Werngard Czechtizky, Stefan Vollmer, Anna M. Rydzik
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 898-907 (2023)
MicroRNAs are attractive therapeutic targets in many diseases, including chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Among microRNA inhibitors antimiRs have been proven successful in lowering aberrant microRNA levels in t
Externí odkaz:
https://doaj.org/article/140a9ff8032c47bc9b3b36ead9a64253
Autor:
Lars M. König, Bodo Brunner, Simon Rothenfußer, Sabine Scheidler, Dmitri Wiederschain, Stefan Endres, Max M. Schnurr, Timothy R. Wagenaar, Hui Cao, Joachim Theilhaber, Kaj Grandien, Petra Scherer, Gabriele Dietert, Monika Braun, Christiane Metz-Weidmann, Felix Gnerlich, Kerstin Jahn-Hofmann, Mike W. Helms
Supplementary Figure S1 shows that RIG-I, MDA and IRF7 mRNA expression are correlated to the Type I IFN signature in melanoma, while MAVS, TBK1 and IRF3 are not. Supplementary Figure S2 shows a list of gene products correlated with RIG-I expression b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a4da953aaf859e66a4a0df15ab8f8b
https://doi.org/10.1158/1535-7163.22505878.v1
https://doi.org/10.1158/1535-7163.22505878.v1
Autor:
Lars M. König, Timothy R. Wagenaar, Simon Rothenfußer, Monika Braun, Hui Cao, Christiane Metz-Weidmann, Gabriele Dietert, Sabine Scheidler, Max Schnurr, Kaj Grandien, Felix Gnerlich, Dmitri Wiederschain, Joachim Theilhaber, Stefan Endres, Kerstin Jahn-Hofmann, Mike W. Helms, Petra Scherer, Bodo Brunner
Publikováno v:
Molecular Cancer Therapeutics. 18:2343-2356
The pattern recognition receptor RIG-I plays an important role in the recognition of nonself RNA and antiviral immunity. RIG-I's natural ligand, triphosphate RNA (ppp-RNA), is proposed to be a valuable addition to the growing arsenal of cancer immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe637e7d26f0964569f49676c0e5b05c
https://doi.org/10.1158/1535-7163.mct-18-1262
https://doi.org/10.1158/1535-7163.mct-18-1262
Autor:
Thomas Carell, André Dallmann, Stefan Schiesser, Martin Rübbelke, Alexander V. Beribisky, Felix Gnerlich, Michael Sattler
Publikováno v:
Chem. Eur. J. 22, 15350-15359 (2016)
Structural features and internal dynamics of inosine- containing RNAs are poorly understood. NMR studies of such RNAs require C-13, N-15-labeling, which cannot be achieved using in vitro transcription as inosine and guanosine are not distinguished by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ad7e1f2c3f9ef1ade2780585ccfb58
https://doi.org/10.1002/chem.201602784
https://doi.org/10.1002/chem.201602784
Autor:
Konstantin M. J. Sparrer, Julian Willibald, Leonhard Möckl, Tobias Halbach, Thomas Carell, Felix Gnerlich, Johannes Harder, Korbinian Brunner, Karl-Klaus Conzelmann, Andreas Beil, Christoph Bräuchle, Fabio Spada
Publikováno v:
Angewandte Chemie. 127:1968-1971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b06108503011cfc8ab238db3e90df0
https://doi.org/10.1002/ange.201409803
https://doi.org/10.1002/ange.201409803
Autor:
Lars M. König, Stefan Endres, Tim Wagenaar, Dmitri Wiederschain, Eric Parmantier, Sabine Scheidler, Joachim Theilhaber, Gabriele Dietert, Monika Braun, Bodo Brunner, Hui Cao, Max Schnurr, Felix Gnerlich, Kerstin Jahn-Hofmann, Simon Rothenfusser, Kaj Grandien, Christiane Metz-Weidmann, Mike W Helms
Publikováno v:
Cancer Research. 79:5024-5024
RIG-I is a highly important cytosolic pattern recognition receptor (PRR) involved in sensing RNA virus infection and inducing interferon (IFN) production. RIG-I’s natural ligand, triphosphate RNA (ppp-RNA), is proposed to be a valuable addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80ddf3fdadd9bafddfe9a2f35e05edb
https://doi.org/10.1158/1538-7445.am2019-5024
https://doi.org/10.1158/1538-7445.am2019-5024
Autor:
Arne S. Schröder, Toni Pfaffeneder, Barbara Steigenberger, Felix Gnerlich, Jessica Steinbacher, Stefan Schiesser, Thomas Carell
Publikováno v:
Angewandte Chemie. 126:321-324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8485ecf56083b6dc99ad1d35994962
https://doi.org/10.1002/ange.201308469
https://doi.org/10.1002/ange.201308469
Autor:
Ila van Kruijsbergen, Joseph R. Ecker, Felix Gnerlich, Miguel Manzanares, Tatjana Sauka-Spengler, Ruth M. Williams, Saartje Hontelez, Juan J. Tena, Upeka Senanayake, Ozren Bogdanovic, Teresa Rayon, Gert Jan C. Veenstra, Michiel Vermeulen, Matthew D. Schultz, José Luis Gómez-Skarmeta, Ethan Ford, Thomas Carell, Ryan Lister, Arne H. Smits, Elisa de la Calle Mustienes
Publikováno v:
Nature Genetics, 48, 417-26
Digital.CSIC. Repositorio Institucional del CSIC
instname
Europe PubMed Central
Nature Genetics, 48, 4, pp. 417-26
Digital.CSIC. Repositorio Institucional del CSIC
instname
Europe PubMed Central
Nature Genetics, 48, 4, pp. 417-26
Bogdanovic, Ozren et al.
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the mechanisms that guide the epigenome through this transition and their evolutionary conservation
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the mechanisms that guide the epigenome through this transition and their evolutionary conservation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5152a6dafd81aa8e27ed7cea190acb5b
http://hdl.handle.net/2066/157230
http://hdl.handle.net/2066/157230
Autor:
Julian Willibald, Johannes Harder, Thomas Carell, Fabio Spada, Karl-Klaus Conzelmann, Felix Gnerlich, Andreas Beil, Leonhard Möckl, Korbinian Brunner, Christoph Bräuchle, Tobias Halbach, Konstantin M. J. Sparrer
Publikováno v:
Angewandte Chemie (International ed. in English). 54(6)
We report the development of dendritic siRNA nanostructures that are able to penetrate even difficult to transfect cells such as neurons with the help of a special receptor ligand. The nanoparticles elicit strong siRNA responses, despite the dendriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163cef8d51b6d42115aac6e3a8d7ae79
https://pubmed.ncbi.nlm.nih.gov/25522332
https://pubmed.ncbi.nlm.nih.gov/25522332
Autor:
Stefan Schiesser, Thomas Carell, Barbara Steigenberger, Felix Gnerlich, Toni Pfaffeneder, Arne S. Schröder, Jessica Steinbacher
Publikováno v:
Angewandte Chemie (International ed. in English). 53(1)
A 5-formyl-2′-deoxycytidine (fdC) phosphoramidite building block that enables the synthesis of fdC-containing DNA with excellent purity and yield has been developed. In combination with phosphoramidites for 5-methyl-dC, 5-hydroxymethyl-dC, and carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66009dfd783763987bb5c2f83876846d
https://pubmed.ncbi.nlm.nih.gov/24281791
https://pubmed.ncbi.nlm.nih.gov/24281791