Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Felix G. Hermann"'
Publikováno v:
Cells, Vol 9, Iss 4, p 873 (2020)
Chimeric antigen receptor (CAR) redirected T cells are efficacious in the treatment of leukemia/lymphoma, however, showed less capacities in eliminating solid tumors which is thought to be partly due to the lack of cytokine support in the tumor lesio
Externí odkaz:
https://doaj.org/article/463e64500cbb464baf1072e73d44cd2e
Publikováno v:
European Respiratory Review, Vol 26, Iss 144 (2017)
Besides cancer and cardiovascular diseases, lung disorders are a leading cause of morbidity and death worldwide. For many disease conditions no effective and curative treatment options are available. Cell therapies offer a novel therapeutic approach
Externí odkaz:
https://doaj.org/article/9b879ece2b3d4c249024cce0e1f1a4dd
Autor:
Nils Ole Schmidt, Felix G. Hermann, Katrin Lamszus, Christine Guenther, Manfred Westphal, Mascha Binder, Nuray Akyüz, Krystian Fita, Lasse Dührsen, Simon Schliffke, Ulf Geumann, Cecile L. Maire, Malte Mohme
Suppl. Fig. 3. Flow cytometry analysis of T-cell surface marker expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82eb31aae80f7cffec6e8d8aa6e1650d
https://doi.org/10.1158/1078-0432.22474902.v1
https://doi.org/10.1158/1078-0432.22474902.v1
Autor:
Nils Ole Schmidt, Felix G. Hermann, Katrin Lamszus, Christine Guenther, Manfred Westphal, Mascha Binder, Nuray Akyüz, Krystian Fita, Lasse Dührsen, Simon Schliffke, Ulf Geumann, Cecile L. Maire, Malte Mohme
Supplementary Legends and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4749c845953303eb940b448c0121eebd
https://doi.org/10.1158/1078-0432.22474893
https://doi.org/10.1158/1078-0432.22474893
Autor:
Nils Ole Schmidt, Felix G. Hermann, Katrin Lamszus, Christine Guenther, Manfred Westphal, Mascha Binder, Nuray Akyüz, Krystian Fita, Lasse Dührsen, Simon Schliffke, Ulf Geumann, Cecile L. Maire, Malte Mohme
Purpose:Mesenchymal stem cells (MSCs) show an inherent brain tumor tropism that can be exploited for targeted delivery of therapeutic genes to invasive glioma. We assessed whether a motile MSC-based local immunomodulation is able to overcome the immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045577fb7d5143af5657646ef160adfb
https://doi.org/10.1158/1078-0432.c.6528933.v1
https://doi.org/10.1158/1078-0432.c.6528933.v1
Autor:
Ursula Dietrich, Lisa Egerer, Christian Gerum, Harald Schwalbe, Frances Brauer, Dorothee von Laer, Felix G. Hermann
Publikováno v:
Journal of Virology. 83:4844-4853
Binding of the human immunodeficiency virus (HIV) envelope glycoprotein (Env) to the cellular CD4 receptor and a chemokine coreceptor initiates a series of conformational changes in the Env subunits gp120 and gp41. Eventually, the trimeric gp41 folds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f5c35abfd9c0ee18b86e95e78119d6
https://doi.org/10.1128/jvi.00666-08
https://doi.org/10.1128/jvi.00666-08
Autor:
Roland Zahn, Felix G. Hermann, Tsanan Giroglou, Dorothee von Laer, Alexander Alexandrov, Patricia Schult-Dietrich, Torston Tonn, Holger Martinius, Christopher Baum, Marc Egelhofer, Stefanie D Roth, Ursula Dietrich
Publikováno v:
Human Gene Therapy. 20:325-336
Cell membrane-anchored (ma) antiviral peptides derived from the C-terminal heptad repeat of the HIV-1 transmembrane glycoprotein gp41 (C-peptides) and expressed from retroviral vectors were shown to efficiently inhibit HIV-1 entry into target cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c05dce6c0e664829a7a3dd0934dbfd
https://doi.org/10.1089/hum.2006.158
https://doi.org/10.1089/hum.2006.158
Autor:
Lisa Egerer, Dorothee von Laer, Frances Brauer, Andreas Volk, Joerg Kahle, Janine Kimpel, Felix G. Hermann
Gene therapeutic strategies for human immunodeficiency virus type 1 (HIV-1) infection could potentially overcome the limitations of standard antiretroviral drug therapy (ART). However, in none of the clinical gene therapy trials published to date, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c0984e0b2453f68ab5b424165f3285
https://europepmc.org/articles/PMC3129562/
https://europepmc.org/articles/PMC3129562/
Autor:
Tsanan Giroglou, Felix G. Hermann, Klaus Kuehlcke, Jan van Lunzen, Dorothee von Laer, Gunda Brandenburg, Tobias Glaunsinger, Christopher Baum, Sonja Naundorf, Ingrid Müller, Holger Martinius, Volker von Baehr, Francis Brauer, Ingrid Stahmer, Sebastian Newrzela, Alexander Alexandrov, Andrea Schilz
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 15(5)
Drug toxicity and viral resistance limit the long-term efficacy of antiviral drug treatment for human immunodeficiency virus (HIV) infection. Thus, alternative therapies need to be explored. We tested the infusion of T lymphocytes transduced with a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617ff8d7fa882244cea1410a3fe9e771
https://pubmed.ncbi.nlm.nih.gov/28182893
https://pubmed.ncbi.nlm.nih.gov/28182893
Autor:
Felix G. Hermann, Caroline Hoffmann, Dorothee von Laer, Matthias T. Dittmar, Isabel Hagmann, Laura Scrivano, Heike Oberwinkler, Sabine Lohrengel
The development of highly active antiviral therapy has resulted in greater expected life spans and slower progression to AIDS for patient infected with human immunodeficiency virus (HIV) (25, 26). However, the emergence of drug-resistant viruses duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfc07d2b900efd83c305a8d96451d7d
https://europepmc.org/articles/PMC1182644/
https://europepmc.org/articles/PMC1182644/