Zobrazeno 1 - 10
of 739
pro vyhledávání: '"Felix Eckstein"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 3, Pp 100485- (2024)
Objective: Osteoarthritis prevalence differs between women and men; whether this is the result of differences in pre-morbid articular or peri-articular anatomical morphotypes remains enigmatic. Albeit sex within humans cannot be reduced to female/mal
Externí odkaz:
https://doaj.org/article/1bd6b0f5d3974b2e84609118dc52aae8
Autor:
Frank W. Roemer, Mylène Jansen, Anne C. A. Marijnissen, Ali Guermazi, Rafael Heiss, Susanne Maschek, Agnes Lalande, Francisco J. Blanco, Francis Berenbaum, Lotte A. van de Stadt, Margreet Kloppenburg, Ida K. Haugen, Christoph H. Ladel, Jaume Bacardit, Anna Wisser, Felix Eckstein, Floris P. J. G. Lafeber, Harrie H. Weinans, Wolfgang Wirth
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Background The IMI-APPROACH cohort is an exploratory, 5-centre, 2-year prospective follow-up study of knee osteoarthritis (OA). Aim was to describe baseline multi-tissue semiquantitative MRI evaluation of index knees and to describe change f
Externí odkaz:
https://doaj.org/article/6129dd5b66b74aeb8ec4206ff308e2b5
Autor:
Olivier Imbert, Henri Deckx, Katy Bernard, Ellen van der Aar, Maria Pueyo, Nadeem Saeed, Thomas Fuerst, Wolfgang Wirth, Philip G. Conaghan, Felix Eckstein
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 4, Pp 100209- (2021)
Objective: This study aims to assess the efficacy of the anticatabolic ‘a disintegrin and metalloproteinase with thrombospondin motif-5’ (ADAMTS-5) inhibitor, S201086/GLPG1972, in slowing cartilage loss in participants with knee osteoarthritis (O
Externí odkaz:
https://doaj.org/article/9b55d61f7398466bae59b4c2c3dbf22b
Autor:
Leticia A Deveza, Win Min Oo, Stefan Lohmander, Xia Wang, Changhai Ding, Felix Eckstein, Wolfgang Wirth, Anthony Harris, Xiaoqian Liu, Sarah Robbins, Sonika Virk, Benny Antony, David Humphries, Christopher Little, James Linklater, Gillian Heller, Karen Schuck, Kirsty Carmichael, R O'Connell, Thomas Buttel
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/0e0ee5b18a744405857d5b965fafb2e9
Autor:
Olivier Imbert, Damien Chimits, Mickaël Guedj, Freddy Lorieau, Katy Bernard, Agnès Lalande, Wolfgang Wirth, Felix Eckstein, Maria Pueyo
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 3, Pp 100188- (2021)
Objectives: Selection of patients with KL radiographic grade 2 and 3 is widely used in clinical trials, but this approach could have some limitations. The purpose of this study performed on OsteoArthritis Initiative (OAI) data is to assess whether ad
Externí odkaz:
https://doaj.org/article/e6fb5dc6cdcd4c0ebe2299168910c630
Autor:
Mylène P. Jansen, Simon C. Mastbergen, Felix Eckstein, Ronald J. van Heerwaarden, Sander Spruijt, Floris P. J. G. Lafeber
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 12 (2021)
Background: In knee osteoarthritis, radiographic joint space width (JSW) is frequently used as a surrogate marker for cartilage thickness; however, longitudinal changes in radiographic JSW have shown poor correlations with those of magnetic resonance
Externí odkaz:
https://doaj.org/article/df3b363106c546f2920eec159726dc27
Autor:
Heide Boeth, Peter C. Raffalt, Aoife MacMahon, A. Robin Poole, Felix Eckstein, Wolfgang Wirth, Frank Buttgereit, Patrik Önnerfjord, Pilar Lorenzo, Cecilia Klint, Anna Pramhed, Georg N. Duda
Publikováno v:
Journal of Experimental Orthopaedics, Vol 6, Iss 1, Pp 1-10 (2019)
Abstract Background An early detection of Osteoarthritis is urgently needed and still not possible until today. The aim of the study was to assess whether molecular biomarkers of cartilage turnover are associated with longitudinal change in knee cart
Externí odkaz:
https://doaj.org/article/d9a185abdbeb43b897822c222321da6e
Autor:
Frank W. Roemer, Felix Eckstein, Georg Duda, Ali Guermazi, Susanne Maschek, Leena Sharma, Wolfgang Wirth
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 1, Iss 3, Pp 100014- (2020)
Purpose: To test whether radiographically normal knees with contralateral radiographic knee osteoarthritis (ROA) (i.e. ‘early OA model’) exhibit MRI-defined structural tissue pathology to a greater extent and show higher rates of progression comp
Externí odkaz:
https://doaj.org/article/f8df37e49e3648298b6807752810efe3
Publikováno v:
Acta Orthopaedica, Vol 89, Iss 4, Pp 406-411 (2018)
Background and purpose — Knee extensor (KE) muscle weakness is a modifiable feature commonly observed in individuals with knee osteoarthritis (KOA) and constitutes a potential target for patient-specific interventions. Therefore, in this study, we
Externí odkaz:
https://doaj.org/article/7eb05ff2e5b74c93bd9d4e287602c0e4
Autor:
Mylène P. Jansen, Susanne Maschek, Ronald J. van Heerwaarden, Simon C. Mastbergen, Wolfgang Wirth, Floris P. J. G. Lafeber, Felix Eckstein
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 2, p 368 (2021)
High tibial osteotomy (HTO) and knee joint distraction (KJD) are joint-preserving treatments that unload the more affected compartment (MAC) in knee osteoarthritis. This post-hoc study compares two-year cartilage-thickness changes after treatment wit
Externí odkaz:
https://doaj.org/article/2281b0b67c3a4184a2055dcf0674baa6