Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Felix E. de Jongh"'
1
Akademický článek
Cost and Clinical Benefits Associated with Oncotype DX® Test in Patients with Early-Stage HR+/HER2- Node-Negative Breast Cancer in the Netherlands
Autor: Felix E. de Jongh, Reva Efe, Kirsten H. Herrmann, Jelle A. Spoorendonk
Publikováno v: International Journal of Breast Cancer, Vol 2022 (2022)
Objectives. Patients with early-stage HR+/HER2- N0 breast cancer may receive adjuvant chemotherapy in combination with surgery. However, chemotherapy does not always lead to improved survival and incurs high healthcare costs and increased adverse eve
Externí odkaz: https://doaj.org/article/d8d1f84ff5734916988b7d1fbc5a758a
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2
Akademický článek
Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor
Autor: Nick Beije, Wendy Onstenk, Jaco Kraan, Anieta M. Sieuwerts, Paul Hamberg, Luc Y. Dirix, Anja Brouwer, Felix E. de Jongh, Agnes Jager, Caroline M. Seynaeve, Ngoc M. Van, John A. Foekens, John W.M. Martens, Stefan Sleijfer
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 11, Pp 647-653 (2016)
BACKGROUND: Preclinical and clinical studies have reported that human epidermal growth factor receptor 2 (HER2) overexpression yields resistance to endocrine therapies. Here the prevalence and prognostic impact of HER2-positive circulating tumor cell
Externí odkaz: https://doaj.org/article/2fc277ad94754fb3a632334527cbac9b
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6
Androgen receptor expression in circulating tumor cells of patients with metastatic breast cancer
Autor: Stefan Sleijfer, Paul Hamberg, Marcel Smid, Mieke Timmermans, Wendy Onstenk, John W.M. Martens, Jaco Kraan, Agnes Jager, Felix E. de Jongh, Ingeborg E. de Kruijff, Anieta M. Sieuwerts
Publikováno v: International Journal of Cancer, 145(4), 1083-1089. Wiley-Liss Inc.
The androgen receptor (AR) has potential clinical relevance in metastatic breast cancer (mBC) since it might be a treatment target and has been associated with endocrine resistance. A minimal-invasive way to determine AR expression on metastatic tumo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c45226ab78823a5922d9d7bd6f866c
https://doi.org/10.1002/ijc.32209
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7
Loss of skeletal muscle index and survival in patients with metastatic colorectal cancer : Secondary analysis of the phase 3 CAIRO3 trial
Autor: Miriam Koopman, Felix E de Jongh, Ankie M.T. van der Velden, Bram Dorresteijn, Sophie A Kurk, Pim A. de Jong, Geert-Jan Creemers, Petra H.M. Peeters, Frans L. G. Erdkamp, Marion Jourdan, Anne M May, Peter A M Kint, Boelo J Poppema, Lieke H.J. Simkens, Manuel L. R. Tjin-A-Ton, B.C. Tanis, Cornelis J. A. Punt, Sandra A Radema
Publikováno v: Cancer Medicine, 9(3), 1033. John Wiley and Sons Ltd
Cancer Medicine
Cancer Medicine, Vol 9, Iss 3, Pp 1033-1043 (2020)
Cancer medicine, 9(3), 1033-1043. John Wiley and Sons Ltd
Cancer Medicine, 9, 1033-1043
Cancer Medicine, 9, 3, pp. 1033-1043
Background Low skeletal muscle index (SMI) in metastatic colorectal cancer (mCRC) patients is associated with poor outcomes. The prognostic impact of SMI changes during consecutive palliative systemic treatments is unknown. Methods This is a retrospe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9423fcb999920710eadfa5693d7cdcb6
https://dspace.library.uu.nl/handle/1874/395432
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8
Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients
Autor: Paul Hamberg, Wendy Onstenk, Silvia Rita Vitale, Caroline M. Seynaeve, Anieta M. Sieuwerts, Anja Brouwer, Jaco Kraan, Stefan Sleijfer, John W.M. Martens, Felix E. de Jongh, Nick Beije, Agnes Jager, Maurice P.H.M. Jansen, John A. Foekens, Ngoc M. Van, Luc Dirix, Michelle van der Vlugt-Daane
Publikováno v: Molecular Oncology, Vol 12, Iss 1, Pp 48-57 (2018)
Molecular Oncology
Molecular Oncology, 12(1), 48-57. John Wiley & Sons Ltd.
Mutations and splice variants in the estrogen receptor (ER) gene, ESR1, may yield endocrine resistance in metastatic breast cancer (MBC) patients. These putative endocrine resistance markers are likely to emerge during treatment, and therefore, its d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b061357250d70117996cfbd320c8978
https://hdl.handle.net/1765/102992
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9
Skeletal muscle mass loss and dose-limiting toxicities in metastatic colorectal cancer patients
Autor: Cornelis J. A. Punt, Manuel L. R. Tjin-A-Ton, Petra H.M. Peeters, B.C. Tanis, Ankie M.T. van der Velden, Felix E de Jongh, Bram Dorresteijn, Peter A M Kint, Pim de Jong, Geert-Jan Creemers, Sophie A Kurk, Rebecca K. Stellato, Miriam Koopman, A. M. May, Lieke H.J. Simkens, Marion Jourdan, Frans L. G. Erdkamp
Publikováno v: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 10(4), 803-813. Wiley-Blackwell
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 4, Pp 803-813 (2019)
Journal of Cachexia, Sarcopenia and Muscle, 10(4), 803. Wiley-Blackwell
Journal of Cachexia, Sarcopenia and Muscle
Background Increasing evidence suggests that severe skeletal muscle index (SMI) loss (sarcopenia) is associated with poor overall survival in metastatic colorectal cancer patients, but its mechanisms are unknown. We recently found, using data of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd37faf96655e2b511007c5e1839fd2
https://pure.amc.nl/en/publications/skeletal-muscle-mass-loss-and-doselimiting-toxicities-in-metastatic-colorectal-cancer-patients(2887e29c-c41f-4f79-8562-1e59ae142ea7).html
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10
An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA
Autor: Lindsay Angus, Silvia Rita Vitale, Anieta M. Sieuwerts, Ngoc M. Van, Agnes Jager, Jaco Kraan, John A. Foekens, Luc Dirix, Paul Hamberg, Stefan Sleijfer, John W.M. Martens, Felix E. de Jongh, Esther A. Reijm, Bianca Mostert, Maurice P.H.M. Jansen, Paolo Vigneri, Nick Beije, Ronald van Marion
Publikováno v: Journal of Molecular Diagnostics, 21(1), 123-137. Elsevier Inc.
The detection of mutated genes in cell-free DNA (cfDNA) in plasma has emerged as an important minimally invasive way to obtain detailed information regarding tumor biology. Reliable determination of circulating tumor–derived DNA, often present at a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85c8ee077606aecb2ad162120e5ca8a
https://pubmed.ncbi.nlm.nih.gov/30296589
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