Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Felix Du"'
Autor:
Xin Wang, Yan Li, Meng Sun, Jiping Zha, Songmao Zheng, Guizhong Liu, Peter Luo, John J Skinner, Kristine She, Jiangchun Xu, Felix Du
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/54d3ae910a7e49a8b32d88e170c68136
Autor:
Aaron Nguyen, Peng Zou, Songmao Zheng, Jianfeng Shi, Guizhong Liu, Yan Li, Felix Du, Peter Luo, Jiangchun Xu
Publikováno v:
Cancer Research. 83:2930-2930
Background: Anti-CD47 therapies have demonstrated promising clinical activities; however, expression of CD47 on many different normal human cell types, including RBCs, serves as a large antigen sink for anti-CD47 antibodies. Blocking CD47 on RBCs, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c26f054b051f976d37ab610ed0bc10
https://doi.org/10.1158/1538-7445.am2023-2930
https://doi.org/10.1158/1538-7445.am2023-2930
Autor:
Guizhong Liu, Zhengxi Dai, Jiagui Qu, Jianfeng Shi, Qi Zhao, Bin Cai, Aaron N. Nguyen, Songmao Zheng, Jiangchun Xu, Yan Li, Felix Du, Peter Luo
Publikováno v:
Cancer Research. 82:2888-2888
Targeting CD28 for systemic T cell activation caused severe cytokine storm and multiorgan failure in an anti-CD28 antibody TGN1412 phase 1 trial. However, tumor specific CD28 targeting in a tumor associated antigen (TAA)×CD28 bispecific format, simi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9e05fd14f8808636aab233c1177071
https://doi.org/10.1158/1538-7445.am2022-2888
https://doi.org/10.1158/1538-7445.am2022-2888
Autor:
Guizhong Liu, Yan Li, Zhengxi Dai, Jiagui Qu, Jianfeng Shi, Qi Zhao, Linhai Qu, Aaron N. Nguyen, Songmao Zheng, Jiangchun Xu, Felix Du, Peter Luo
Publikováno v:
Cancer Research. 82:2869-2869
Bispecific T-cell engagers (TCEs) have shown therapeutic promise in treating hematologic cancers. However, their utility in treating solid tumors has yet to be effectively demonstrated due to on-target off-tumor toxicity and systemic cytokine release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1064a14926e315a16ec2b8555af8a8c6
https://doi.org/10.1158/1538-7445.am2022-2869
https://doi.org/10.1158/1538-7445.am2022-2869
Autor:
Bin Cai, Aaron N. Nguyen, Songmao Zheng, Jianfeng Shi, Guizhong Liu, Yan Li, Felix Du, Peter Luo, Jiangchun Xu
Publikováno v:
Cancer Research. 82:4257-4257
Anti-CD47 antibodies of the IgG4 isotype have shown promising activities in clinical trials for hematologic malignancies, mainly in the combination setting. To overcome the fundamental challenge of developing an anti-CD47 antibody of an active Fc iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ae6dcd030f11fe62c816a4cbc2f4f6
https://doi.org/10.1158/1538-7445.am2022-4257
https://doi.org/10.1158/1538-7445.am2022-4257
Autor:
Gary Edward Richardson, Anthony W. Tolcher, Michelle Frances Morris, Paul L. de Souza, Anis Hamid, Xiaohong She, Lvyu Zhu, Hongyan Wang, Songmao Zheng, Guizhong Liu, Yan Li, Fangyong Felix Du, Steven Fischkoff, Hua Gong, Jiping Zha, Peter Luo
Publikováno v:
Journal of Clinical Oncology. 40:e17601-e17601
e17601 Background: SAFEbody ADG126, a masked version of NEObody ADG116 (ESMO IO Conference Abstract #394, NCT04501276), targets a unique species-conserved CTLA-4 epitope with preclinical safety and efficacy profiles superior to ipilimumab, an approve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57727ffb4f32c2cd0edd03411be79e37
https://doi.org/10.1200/jco.2022.40.16_suppl.e17601
https://doi.org/10.1200/jco.2022.40.16_suppl.e17601
Autor:
Felix Dube
Publikováno v:
Potchefstroom Electronic Law Journal, Vol 27 (2024)
The retirement of Justice Johan Froneman from the Constitutional Court of South Africa provides an ideal opportunity to reflect on his approach to collegiality and tolerance of difference. Like his predecessors, Justice Froneman navigated a delicate
Externí odkaz:
https://doaj.org/article/b750456f46654dc88938a82e4f90ed4b
Autor:
Songmao Zheng, Jianfeng Shi, Jiangchun Xu, Bin Cai, Yan Li, Peter Luo, Felix Du, Aaron N. Nguyen, Guizhong Liu
Publikováno v:
Blood. 138:3342-3342
Binding of the CD47 membrane protein, overexpressed on many tumor types, to the SIRPα inhibitory receptor on myeloid cells results in the inhibition of the activation of macrophages and other phagocytes against tumors. Therapies targeting the CD47/S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff186982c605f774a11405c0bcbfd20
https://doi.org/10.1182/blood-2021-152130
https://doi.org/10.1182/blood-2021-152130
Publikováno v:
Cancer Research. 81:1853-1853
As the first approved immune checkpoint inhibitor targeting CTLA-4, ipilimumab has achieved great clinical success in cancer immunotherapy, particularly in combination with anti-PD-1 therapy. However, ipilimumab can also induce severe and sometimes f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1347cb4c78bdba8b3eef22c9e7c016f7
https://doi.org/10.1158/1538-7445.am2021-1853
https://doi.org/10.1158/1538-7445.am2021-1853
Autor:
Felix Duperrier
Publikováno v:
XVII-XVIII, Vol 80 (2023)
In his Essays upon Epitaphs, William Wordsworth invites the reader to reflect on the ways in which the past sustains the present. Despite its ordinary status, the epitaph is treated as a complex object that gives a material shape to immaterial realit
Externí odkaz:
https://doaj.org/article/029f709d773a4ccc8524cfcc249df717