Zobrazeno 1 - 10
of 503
pro vyhledávání: '"Felix CA"'
Autor:
Lazaro M. Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Thomas K. Karikari, Nicholas J. Ashton, Andréa L. Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C. Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Neuronal dysfunction and cognitive deterioration in Alzheimer’s disease (AD) are likely caused by multiple pathophysiological factors. However, mechanistic evidence in humans remains scarce, requiring improved non-invasive techniques and i
Externí odkaz:
https://doaj.org/article/d1d394702b194a57a434755661c25a8f
Autor:
Ishier Raote, Ann-Helen Rosendahl, Hanna-Maria Häkkinen, Carina Vibe, Ismail Küçükaylak, Mugdha Sawant, Lena Keufgens, Pia Frommelt, Kai Halwas, Katrina Broadbent, Marina Cunquero, Gustavo Castro, Marie Villemeur, Julian Nüchel, Anna Bornikoel, Binita Dam, Ravindra K. Zirmire, Ravi Kiran, Carlo Carolis, Jordi Andilla, Pablo Loza-Alvarez, Verena Ruprecht, Colin Jamora, Felix Campelo, Marcus Krüger, Matthias Hammerschmidt, Beate Eckes, Ines Neundorf, Thomas Krieg, Vivek Malhotra
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies are lacking. A pro
Externí odkaz:
https://doaj.org/article/252118aa60de4fe1a96942bcae197b43
Autor:
Diogo C. Vaz, Chia-Ching Lin, John J. Plombon, Won Young Choi, Inge Groen, Isabel C. Arango, Andrey Chuvilin, Luis E. Hueso, Dmitri E. Nikonov, Hai Li, Punyashloka Debashis, Scott B. Clendenning, Tanay A. Gosavi, Yen-Lin Huang, Bhagwati Prasad, Ramamoorthy Ramesh, Aymeric Vecchiola, Manuel Bibes, Karim Bouzehouane, Stephane Fusil, Vincent Garcia, Ian A. Young, Fèlix Casanova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract As CMOS technologies face challenges in dimensional and voltage scaling, the demand for novel logic devices has never been greater, with spin-based devices offering scaling potential, at the cost of significantly high switching energies. Alt
Externí odkaz:
https://doaj.org/article/4cb309a42c9649b39a25f413399a5c42
Autor:
Lazaro M. Sanchez-Rodriguez, Ahmed F. Khan, Quadri Adewale, Gleb Bezgin, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Hongxiu Jiang, Xiaoqian Chai, Felix Carbonell, Pedro Rosa-Neto, Yasser Iturria-Medina
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The molecular mechanisms underlying neuronal dysfunction in Alzheimer’s disease (AD) remain uncharacterized. Here, we identify genes, molecular pathways and cellular components associated with whole-brain dysregulation caused by amyloid-beta (Aβ)
Externí odkaz:
https://doaj.org/article/1657c77c5c334d1eb95796dc2572b831
Autor:
Ivan Castello-Serrano, Frederick A Heberle, Barbara Diaz-Rohrer, Rossana Ippolito, Carolyn R Shurer, Pablo Lujan, Felix Campelo, Kandice R Levental, Ilya Levental
Publikováno v:
eLife, Vol 12 (2024)
The organelles of eukaryotic cells maintain distinct protein and lipid compositions required for their specific functions. The mechanisms by which many of these components are sorted to their specific locations remain unknown. While some motifs media
Externí odkaz:
https://doaj.org/article/f5709ab00f394791bd1057501fc2bfaa
Autor:
Ana Dias-Carvalho, Mariana Ferreira, Ana Reis-Mendes, Rita Ferreira, Maria de Lourdes Bastos, Eduarda Fernandes, Susana Isabel Sá, João Paulo Capela, Félix Carvalho, Vera Marisa Costa
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31608- (2024)
Doxorubicin (DOX) is an anthracycline used to treat a wide range of tumours. Despite its effectiveness, it is associated with a long range of adverse effects, of which cognitive deficits stand out. The present study aimed to assess the neurologic adv
Externí odkaz:
https://doaj.org/article/6f95bfc09f1245b5980cbd637fdda73e
Autor:
Olivia Ferrández, Santiago Grau, Elena Colominas-González, María Eugenia Navarrete-Rouco, Nuria Carballo-Martínez, Marta De Antonio-Cuscó, Xènia Fernández-Sala, Laura Rio-No, Oscar Fando Romera, Maria Berzosa Malagon, Sergio Pineda Rodriguez, Noelia Torres Rius, Xavier Duran-Jordà, Cristina Rodríguez-Caba, Jordi Casas-Sánchez, Félix Caro Herranz, Caridad Pontes-García
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
GoalTo describe the experience of a dispensing model of outpatient hospital medicines (OHM) via collaboration of hospital and community pharmacies, and to explore patient satisfaction with the strategy as compared with the hospital pharmacy only serv
Externí odkaz:
https://doaj.org/article/2f6692eee15048afb72f4000ba15f009
Autor:
Junhyeon Jo, Yuan Peisen, Haozhe Yang, Samuel Mañas-Valero, José J. Baldoví, Yao Lu, Eugenio Coronado, Fèlix Casanova, F. Sebastian Bergeret, Marco Gobbi, Luis E. Hueso
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract Two-dimensional magnets and superconductors are emerging as tunable building-blocks for quantum computing and superconducting spintronic devices, and have been used to fabricate all two-dimensional versions of traditional devices, such as Jo
Externí odkaz:
https://doaj.org/article/d44ec4c9ff06465fac5ea5a39af82e9e
Publikováno v:
Inorganics, Vol 12, Iss 7, p 187 (2024)
When synthesizing the versatile precursors (NMe4)[Ni(CF3)3(MeCN)] we recently encountered the problem that marked amounts of C2F5 were incorporated instead of CF3 under the chosen reaction conditions forming mixed-ligand nickelates [Ni(CF3)x(C2F5)y(M
Externí odkaz:
https://doaj.org/article/acaeb62823f24bf9a85dcd3ac5b95e35
Autor:
Pablo Lujan, Carla Garcia-Cabau, Yuichi Wakana, Javier Vera Lillo, Carmen Rodilla-Ramírez, Hideaki Sugiura, Vivek Malhotra, Xavier Salvatella, Maria F Garcia-Parajo, Felix Campelo
Publikováno v:
eLife, Vol 12 (2024)
Secretory proteins are sorted at the trans-Golgi network (TGN) for export into specific transport carriers. However, the molecular players involved in this fundamental process remain largely elusive. Here, we identified the human transmembrane protei
Externí odkaz:
https://doaj.org/article/6941725be9904fe88ea7ca8d85a07ae9