Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Felix Behrens"'
Autor:
Chao Zhang, Michael Rehman, Xin Tian, Steven Lim Cho Pei, Jianlei Gu, Thomas A. Bell, Ke Dong, Ming Shen Tham, Yiqiang Cai, Zemeng Wei, Felix Behrens, Anton M. Jetten, Hongyu Zhao, Monkol Lek, Stefan Somlo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mouse models of autosomal dominant polycystic kidney disease (ADPKD) show that intact primary cilia are required for cyst growth following the inactivation of polycystin-1. The signaling pathways underlying this process, termed cilia-depende
Externí odkaz:
https://doaj.org/article/be382d3d7234491f9e63a463c7ab57e7
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-26 (2020)
Abstract Extracellular vesicles (EVs) are small, lipid bilayer-delimited particles of cellular origin that recently gained increasing attention for their potential use as diagnostic biomarkers, and beyond that for their role in intercellular communic
Externí odkaz:
https://doaj.org/article/a265eb1641c64f43ac0eb2a3b2b3d895
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Pulmonary hypertension (PH) represents a grave condition associated with high morbidity and mortality, emphasizing a desperate need for innovative and targeted therapeutic strategies. Cumulative evidence suggests that inflammation and dysregulated im
Externí odkaz:
https://doaj.org/article/92a842261ea5473184828eb581cf6a38
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3858 (2021)
Pneumonia due to respiratory infection with most prominently bacteria, but also viruses, fungi, or parasites is the leading cause of death worldwide among all infectious disease in both adults and infants. The introduction of modern antibiotic treatm
Externí odkaz:
https://doaj.org/article/b1048e89b6734e79bbbabbd4cc85965e
Autor:
Szandor Simmons, Erik Asmus, Weronika Karle, Markus Brack, Corey Wittig, Felix Behrens, Leander Reinshagen, Lasti Erfinanda, Laura Michalick, Patrick Smeele, Charissa van den Brom, Toralf Kaiser, Leif Sander, Ulf Landmesser, Arash Haghikia, Robert Preissner, Harm Bogaard, Martin Witzenrath, Wolfgang Kuebler, Robert Szulcek
Publikováno v:
Physiology. 38
Cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl- channel and ABC transporter; its mutations cause the clinical picture of cystic fibrosis (CF). Of late, CFTR has emerged as an important regulator of platelet function, as CFTR dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d4914415fbe352a765d0ab2f9fab8d
https://doi.org/10.1152/physiol.2023.38.s1.5729301
https://doi.org/10.1152/physiol.2023.38.s1.5729301
Autor:
Erik Asmus, Weronika Karle, Markus C. Brack, Corey Wittig, Felix Behrens, Leander Reinshagen, Moritz Pfeiffer, Sabrina Schulz, Bertina Mandzimba-Maloko, Lasti Erfinanda, Paul L. Perret, Laura Michalick, Patrick J. Smeele, Endry H.T. Lim, Charissa E. van den Brom, Alexander B.A. Vonk, Toralf Kaiser, Norbert Suttorp, Stefan Hippenstiel, Leif E. Sander, Florian Kurth, Ursula Rauch, Ulf Landmesser, Arash Haghikia, Robert Preissner, Harm J. Bogaard, Martin Witzenrath, Wolfgang M. Kuebler, Robert Szulcek, Szandor Simmons
Publikováno v:
Asmus, E, Karle, W, Brack, M C, Wittig, C, Behrens, F, Reinshagen, L, Pfeiffer, M, Schulz, S, Mandzimba-Maloko, B, Erfinanda, L, Perret, P L, Michalick, L, Smeele, P J, Lim, E H T, van den Brom, C E, Vonk, A B A, Kaiser, T, Suttorp, N, Hippenstiel, S, Sander, L E, Kurth, F, Rauch, U, Landmesser, U, Haghikia, A, Preissner, R, Bogaard, H J, Witzenrath, M, Kuebler, W M, Szulcek, R & Simmons, S 2023, ' Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients ', The European respiratory journal, vol. 61, no. 3, 2202009 . https://doi.org/10.1183/13993003.02009-2022
European respiratory journal, 61(3). European Respiratory Society
The European respiratory journal, 61(3):2202009. European Respiratory Society
European respiratory journal, 61(3). European Respiratory Society
The European respiratory journal, 61(3):2202009. European Respiratory Society
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators reduce agonist-induced platelet activation and function. CFTR modulators, such as ivacaftor, present a promising therapeutic strategy in thrombocytopathies, including severe COVID-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d012e8c4eadda39018301e898b24c4
https://doi.org/10.1183/13993003.02009-2022
https://doi.org/10.1183/13993003.02009-2022
Publikováno v:
Deutsche Zeitschrift für Onkologie. 54:9-13
ZusammenfassungDie lokale Strahlentherapie spielt in der kurativen wie palliativen Krebsbehandlung eine große Rolle. Tumoransprechen außerhalb des bestrahlten Feldes werden als abskopaler Effekt (von lat. „ab“=weg von und „scopus“=Ziel) bez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::493751d038d38adb9958ccc120b7c37d
https://doi.org/10.1055/a-1731-6050
https://doi.org/10.1055/a-1731-6050
Autor:
Hendrik Bartolomaeus, Johannes Holle, Ulrike Loeber, Felix Behrens, Theda Bartolomaeus, Harithaa Anandakumar, Moritz I Wimmer, Dai Long Vu, Sabrina Y Geisberger, Kai-Uwe Eckardt, Sofia Kirke Forslund, Andrea Thürmer, Victoria McParland, Jennifer A Kirwan, Dominik Müller, Nicola Wilck
Publikováno v:
Hypertension. 79
Introduction: Chronic inflammation is a major risk factor for cardiovascular disease in chronic kidney disease (CKD). The underlying mechanisms are incompletely understood, but may be linked to gut dysbiosis. We aim to describe the microbiota-immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce0bc50a4850d303edf1262e85f5870
https://doi.org/10.1161/hyp.79.suppl_1.013
https://doi.org/10.1161/hyp.79.suppl_1.013
Autor:
Laura Michalick, Bertina Mandzimba‐Maloko, Shima Hamedi, Melanie Dohmen, Markus C. Brack, Sabrina Schulz, Felix Behrens, Szandor Simmons, Holger Müller‐Redetzky, Norbert Suttorp, Florian Kurth, Victor M. Corman, Andreas C. Hocke, Martin Witzenrath, Stefan Hippenstiel, Wolfgang M. Kuebler
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aeb500c7894a26da273debfa9f4aefe
https://doi.org/10.1096/fasebj.2022.36.s1.r3130
https://doi.org/10.1096/fasebj.2022.36.s1.r3130
Autor:
Johannes Holle, Hendrik Bartolomaeus, Ulrike Löber, Felix Behrens, Theda U.P. Bartolomaeus, Harithaa Anandakumar, Moritz I. Wimmer, Dai Long Vu, Mathias Kuhring, Ulrike Brüning, Andras Maifeld, Sabrina Geisberger, Stefan Kempa, Fabian Schumacher, Burkhard Kleuser, Philip Bufler, Uwe Querfeld, Stefanie Kitschke, Denise Engler, Leonard D. Kuhrt, Oliver Drechsel, Kai-Uwe Eckardt, Sofia K. Forslund, Andrea Thürmer, Victoria McParland, Jennifer A. Kirwan, Nicola Wilck, Dominik Müller
Publikováno v:
JASN
CKD is characterized by a sustained proinflammatory response of the immune system, promoting hypertension and cardiovascular disease. The underlying mechanisms are incompletely understood but may be linked to gut dysbiosis. Dysbiosis has been describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1576c96ec3294729cc83885c48ccb19c
https://pubmed.ncbi.nlm.nih.gov/35985814
https://pubmed.ncbi.nlm.nih.gov/35985814