Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Felix A. Deuss"'
Publikováno v:
Journal of Biological Chemistry. 292:11413-11422
T cell immunoglobulin and ITIM domain (TIGIT) is an inhibitory receptor expressed on the surface of natural killer (NK) cells. TIGIT recognizes nectin and nectin-like adhesion molecules and thus plays a critical role in the innate immune response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40a7b84a5addf60786fd6111bdde386
https://doi.org/10.1074/jbc.m117.786483
https://doi.org/10.1074/jbc.m117.786483
Autor:
William R. Heath, Hariprasad Venugopal, Carmen Llerena, Felix A. Deuss, Irina Caminschi, Richard Berry, Zhihui Fu, Alex J. Fulcher, Jessica Li, Benjamin S. Gully, Mireille H. Lahoud, Jamie Rossjohn
Publikováno v:
The Journal of Biological Chemistry
DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guanosine oligonucleotides, a motif often seen in bacterial or vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855dbccf65e93753130becd900b8e0fc
https://doi.org/10.1074/jbc.ra120.016451
https://doi.org/10.1074/jbc.ra120.016451
Autor:
FELIX ALEXANDER DEUSS
This thesis explores the three-dimensional structures of a family of immune receptors known as the Nectin receptors. Recently, the Nectin receptors have been in the spotlight for their ability to control cancer. The results presented here shed light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f27e43d01e1a851141d8db56a7893ff
Autor:
Jamie Rossjohn, Felix A. Deuss, Philippa M. Saunders, Gautham R. Balaji, Andrew G. Brooks, Jie Lin, Julian P. Vivian, Richard Berry, Dene R. Littler
Publikováno v:
Journal of Biological Chemistry. 289:23753-23763
The ability of CMVs to evade the immune system of the host is dependent on the expression of a wide array of glycoproteins, many of which interfere with natural killer cell function. In murine CMV, two large protein families mediate this immune-evasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec40fd90799765a1aa18576a0a043f3
https://doi.org/10.1074/jbc.m114.584128
https://doi.org/10.1074/jbc.m114.584128
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 75:e91-e91
Summary CD96, DNAM-1, and TIGIT constitute a group of immunoglobulin superfamily receptors that are key regulators of tumor immune surveillance. Within this axis, CD96 recognizes the adhesion molecule nectin-like protein-5 (necl-5), although the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4070f65fa7468bf857e9c3c7a6ffbd
https://doi.org/10.1107/s2053273319094658
https://doi.org/10.1107/s2053273319094658
Autor:
Lucy C. Sullivan, Michiko Mirams, Gautham R. Balaji, Joseph A. Trapani, Jacqueline M.L. Widjaja, Felix A. Deuss, Jamie Rossjohn, Daniel M. Andrews, Nicole L. LaGruta, Natasha Sosnin, Richard Berry, Andrew G. Brooks
Murine natural killer (NK) cells are regulated by the interaction of Ly49 receptors with major histocompatibility complex class I molecules (MHC-I). Although the ligands for inhibitory Ly49 were considered to be restricted to classical MHC (MHC-Ia),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bb6ec76481fbb0d7e078a5875e46bf
https://orca.cardiff.ac.uk/id/eprint/100015/1/18740.full.pdf
https://orca.cardiff.ac.uk/id/eprint/100015/1/18740.full.pdf
Autor:
Lucy C. Sullivan, Catherine A. Forbes, Natasha May-Yoke Ng, Alexandra J. Corbett, Melissa J. Call, Richard Berry, Felix A. Deuss, Andrew G. Brooks, Anthony A. Scalzo, Philippa M. Saunders, Adrian Dale McAlister, Travis Clarke Beddoe, Julian P. Vivian, Matthew A. Perugini, Mariapia A. Degli-Esposti, Jacqueline M.L. Widjaja, Jérôme D. Coudert, Jie Lin, Jamie Rossjohn
Publikováno v:
Nature immunology. 14(7)
Activating and inhibitory receptors on natural killer (NK) cells have a crucial role in innate immunity, although the basis of the engagement of activating NK cell receptors is unclear. The activating receptor Ly49H confers resistance to infection wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffabdd8a143160caf7ce0979e598959
https://pubmed.ncbi.nlm.nih.gov/23666294
https://pubmed.ncbi.nlm.nih.gov/23666294
Publikováno v:
Free Radical Biology and Medicine. 76:S81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee1d7cc3b1edf788b5ea061eaa266b8
https://doi.org/10.1016/j.freeradbiomed.2014.10.286
https://doi.org/10.1016/j.freeradbiomed.2014.10.286