Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Felix, Broecker"'
Autor:
Christian Willy, Joachim J. Bugert, Annika Y. Classen, Li Deng, Anja Düchting, Justus Gross, Jens A. Hammerl, Imke H. E. Korf, Christian Kühn, Simone Lieberknecht-Jouy, Christine Rohde, Markus Rupp, Maria J. G. T. Vehreschild, Kilian Vogele, Sarah Wienecke, Martin Witzenrath, Silvia Würstle, Holger Ziehr, Karin Moelling, Felix Broecker
Publikováno v:
Viruses, Vol 15, Iss 2, p 588 (2023)
Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current situation (2023) of applied phage therapy and supporting research in Germany. The authors, an int
Externí odkaz:
https://doaj.org/article/f28fe83aafa34f0aaeb86b8c94bc7cc1
Autor:
Mark J. Bailey, James Duehr, Harrison Dulin, Felix Broecker, Julia A. Brown, Fortuna O. Arumemi, Maria C. Bermúdez González, Victor H. Leyva-Grado, Matthew J. Evans, Viviana Simon, Jean K. Lim, Florian Krammer, Rong Hai, Peter Palese, Gene S. Tan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Zika virus infection can cause severe disease in humans and there are currently no specific treatments or vaccines. Here, Bailey et al. isolate antibodies recognizing non-structural protein NS1 and show that they protect mice from disease by an Fc-de
Externí odkaz:
https://doaj.org/article/903f1b10954c412ebb5d22ba6f570d2b
Autor:
Felix Broecker
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13526 (2021)
The evolutionary origin of the genome remains elusive. Here, I hypothesize that its first iteration, the protogenome, was a multi-ribozyme RNA. It evolved, likely within liposomes (the protocells) forming in dry-wet cycling environments, through the
Externí odkaz:
https://doaj.org/article/88747adcb0c24fdd9c3e01a9d008985a
Autor:
Felix Broecker, Karin Moelling
Publikováno v:
Microorganisms, Vol 9, Iss 12, p 2538 (2021)
Viral infections as well as changes in the composition of the intestinal microbiota and virome have been linked to cancer. Moreover, the success of cancer immunotherapy with checkpoint inhibitors has been correlated with the intestinal microbial comp
Externí odkaz:
https://doaj.org/article/c1ecc768897e4b5a8ba2b8a57a742693
Autor:
Felix Broecker
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 20 (2021)
Viruses are the most abundant biological entities on Earth, with an estimated total of 1031 virions [...]
Externí odkaz:
https://doaj.org/article/799d4b7ee374470ea9e84f580742783c
Autor:
Arun Naini, Max Peter Bartetzko, Someswara Rao Sanapala, Felix Broecker, Victoria Wirtz, Marilda P. Lisboa, Sharavathi G. Parameswarappa, Daniel Knopp, Jessica Przygodda, Matthias Hakelberg, Rosalind Pan, Axay Patel, Laurent Chorro, Arthur Illenberger, Christopher Ponce, Srinivas Kodali, Jacqueline Lypowy, Annaliesa S. Anderson, Robert G. K. Donald, Arne von Bonin, Claney L. Pereira
Publikováno v:
JACS Au. 2:2135-2151
Autor:
Mark J. Bailey, Felix Broecker, James Duehr, Fortuna Arumemi, Florian Krammer, Peter Palese, Gene S. Tan
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Zika virus is a mosquito-borne flavivirus which can cause severe disease in humans, including microcephaly and other congenital malformations in newborns and Guillain-Barré syndrome in adults. There are currently no approved prophylactics o
Externí odkaz:
https://doaj.org/article/9217ba9d42f64538ab464d7b2d6d5e38
Autor:
Karin Moelling, Felix Broecker
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The discovery of exoplanets within putative habitable zones revolutionized astrobiology in recent years. It stimulated interest in the question about the origin of life and its evolution. Here, we discuss what the roles of viruses might have been at
Externí odkaz:
https://doaj.org/article/63ddb6ba2bb94dbbbe7978647b3a1e20
Autor:
Felix Broecker, Karin Moelling
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Virus-derived sequences and transposable elements constitute a substantial portion of many cellular genomes. Recent insights reveal the intimate evolutionary relationship between these sequences and various cellular immune pathways. At the most basic
Externí odkaz:
https://doaj.org/article/651ea546cd0b4a64a1a21d0f7610d5d2
Autor:
Karin Moelling, Felix Broecker
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3476 (2021)
Viroids are non-coding circular RNA molecules with rod-like or branched structures. They are often ribozymes, characterized by catalytic RNA. They can perform many basic functions of life and may have played a role in evolution since the beginning of
Externí odkaz:
https://doaj.org/article/0be5e613a05c4621978bd5b937bcd82d