Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease

Autor: Chun-Shu Wong, Clarisa M. Buckner, Silvia Lucena Lage, Luxin Pei, Felipe L. Assis, Eric W. Dahlstrom, Sarah L. Anzick, Kimmo Virtaneva, Adam Rupert, Jeremy L. Davis, Ting Zhou, Elizabeth Laidlaw, Maura Manion, Frances Galindo, Megan Anderson, Catherine A. Seamon, Michael C. Sneller, Andrea Lisco, Claire Deleage, Stefania Pittaluga, Susan Moir, Irini Sereti

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Low nadir CD4 T-cell counts in HIV+ patients are associated with high morbidity and mortality and lasting immune dysfunction, even after antiretroviral therapy (ART). The early events of immune recovery of T cells and B cells in severely lymphopenic

Externí odkaz: https://doaj.org/article/0ae51d691b0641559c9ba2d6466a68a7

From Lesions to Viral Clones: Biological and Molecular Diversity amongst Autochthonous Brazilian Vaccinia Virus

Autor: Graziele Pereira Oliveira, Mauricio Teixeira Lima, Ana Cláudia de Andrade, Felipe L. Assis, Paulo César Peregrino Ferreira, Gabriel Magno de Freitas Almeida, Giliane de Souza Trindade, Jônatas Santos Abrahão, Jonas D. Albarnaz, Rafael Calixto, José Diomedes Barbosa Neto, Erna Geessien Kroon, Cairo H.S. de Oliveira

Publikováno v: Viruses, Vol 7, Iss 3, Pp 1218-1237 (2015)
Viruses
Volume 7
Issue 3
Pages 1218-1237

Vaccinia virus (VACV) has had an important role for humanity because of its use during the smallpox eradication campaign. VACV is the etiologic agent of the bovine vaccinia (BV), an emerging zoonosis that has been associated with economic, social, ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ac118d280e63db0c5d5d90f3737571
https://doi.org/10.3390/v7031218

Genome Characterization of the First Mimiviruses of Lineage C Isolated in Brazil

Autor: Felipe L. Assis, Jônatas Santos Abrahão, Fábio P. Dornas, Paulo V. M. Borato, Raíssa Nunes dos Santos, Philippe Colson, Fabrício Souza Campos, Ana Cláudia Franco, Ana Paula Moreira Franco-Luiz, Bernard La Scola

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Frontiers in Microbiology, 2017, 8, pp.2562. ⟨10.3389/fmicb.2017.02562⟩
Frontiers in Microbiology, Frontiers Media, 2017, 8, pp.2562. ⟨10.3389/fmicb.2017.02562⟩

International audience; The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba polyphaga mimivirus (APMV), in 2003. In this work, we describe the genome analysis of two new mimivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53713e191b95bc63855ae2618586b0d4
http://journal.frontiersin.org/article/10.3389/fmicb.2017.02562/full

In vitro susceptibility to ST-246 and Cidofovir corroborates the phylogenetic separation of Brazilian Vaccinia virus into two clades

Autor: Nathália F.S. Rodrigues, Galileu Barbosa Costa, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Mariana A. Pires, Felipe L. Assis, Danilo Bretas de Oliveira

Publikováno v: Antiviral research. 152

The Orthopoxvirus (OPV) genus of the Poxviridae family contains several human pathogens, including Vaccinia virus (VACV), which have been implicating in outbreaks of a zoonotic disease called Bovine Vaccinia in Brazil. So far, no approved treatment e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01206a558ddbb7169a6d3e00b1a0e5c8
https://pubmed.ncbi.nlm.nih.gov/29427676

The Investigation of Promoter Sequences of Marseilleviruses Highlights a Remarkable Abundance of the AAATATTT Motif in Intergenic Regions

Autor: Erna Geessien Kroon, Cláudio A. Bonjardim, Felipe L. Assis, Thalita Souza Arantes, Flávio Guimarães da Fonseca, Mauricio Teixeira Lima, Bernard La Scola, Rodrigo Araújo Lima Rodrigues, Philippe Colson, Jônatas Santos Abrahão, Graziele Pereira Oliveira

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2017, 91 (21), pp.1088-1105. ⟨10.1128/JVI.01088-17⟩
Journal of Virology, 2017, 91 (21), pp.1088-1105. ⟨10.1128/JVI.01088-17⟩

Viruses display a wide range of genomic profiles and, consequently, a variety of gene expression strategies. Specific sequences associated with transcriptional processes have been described in viruses, and putative promoter motifs have been elucidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74706cd6b4d244b7b55c1fa8952f4e06
https://hal.archives-ouvertes.fr/hal-01730469/document