Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Felipe Guapo"'
Autor:
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2785 (2024)
Gene therapy holds great promise for the treatment of severe diseases, and adeno-associated virus (AAV) vectors have emerged as valuable tools in this field. However, challenges such as immunogenicity and high production costs complicate the commerci
Externí odkaz:
https://doaj.org/article/8355e1c74a384811991deb81932df610
Autor:
Lisa Strasser, Stefano Boi, Felipe Guapo, Nicholas Donohue, Niall Barron, Alana Rainbow-Fletcher, Jonathan Bones
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11499 (2021)
Adeno-associated viral (AAV) vectors are widely used for gene therapy, providing treatment for diseases caused by absent or defective genes. Despite the success of gene therapy, AAV manufacturing is still challenging, with production yields being lim
Externí odkaz:
https://doaj.org/article/93e3678698304bf1bc3c91fc10ee7d88
Autor:
Felipe Guapo, Tomos E. Morgan, Florian Füssl, Ian M. Anderson, Daniel Forsey, Jonathan Bones, Lisa Strasser
Publikováno v:
Analytical Chemistry
Adeno-associated virus (AAV)-based gene therapy is a rapidly developing field, requiring analytical methods for detailed product characterization. One important quality attribute of AAV products that requires monitoring is the amount of residual empt
Autor:
Marina Castro-Rivadeneyra, Ioanna Tzani, Paul Kelly, Lisa Strasser, Felipe Guapo, Ciara Tierney, Michelle Chain, Lin Zhang, Martin Clynes, Barry L. Karger, Niall Barron, Jonathan Bones, Colin Clarke
Chinese hamster ovary (CHO) cells are used to produce almost 90% of therapeutic monoclonal antibodies (mAbs). The annotation of non-canonical translation events in these cellular factories remains incomplete, limiting not only our ability to study CH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e542ec0a048420331458321dd0f2797
https://doi.org/10.1101/2022.01.20.475618
https://doi.org/10.1101/2022.01.20.475618
Autor:
Felipe Guapo, Niall Barron, Jonathan Bones, Nicholas Donohue, Lisa Strasser, Alana Rainbow-Fletcher, Stefano Boi
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11499, p 11499 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11499, p 11499 (2021)
Adeno-associated viral (AAV) vectors are widely used for gene therapy, providing treatment for diseases caused by absent or defective genes. Despite the success of gene therapy, AAV manufacturing is still challenging, with production yields being lim
Adeno-associated virus (AAV) represent a widely used delivery mechanism for gene therapy treatments currently being developed. The size and complexity of these molecules requires the development of sensitive analytical methods for detailed product ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670db6ad6624cdd9e8953a233c88312d
https://doi.org/10.1101/2021.08.11.455907
https://doi.org/10.1101/2021.08.11.455907
Adeno-associated virus (AAV)-based cell and gene therapy is a rapidly developing field, requiring analytical methods for detailed product characterization. One important quality attribute of AAV products that requires monitoring is the amounts of res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f475bf47cdf40eb9670fb01f32b1f6c7
https://doi.org/10.1101/2021.07.06.451264
https://doi.org/10.1101/2021.07.06.451264
Autor:
del Melo, Felipe Guapo
Bombus terrestris (L.) is one of the most important native and commercial pollinator species worldwide. Along with other pollinators their populations are in decline due to a multifactorial phenomenon that includes the extensive use of neonicotinoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______223::d5f0c8c115548c8e6db2cc8cff4afe4d
https://mural.maynoothuniversity.ie/16813/
https://mural.maynoothuniversity.ie/16813/
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 207:114427
Adeno-associated virus (AAV) represent a widely used delivery mechanism for gene therapy treatments currently being developed. The size and complexity of these molecules requires the development of sensitive analytical methods for detailed product ch