Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Felipe G. Sandoval"'
Autor:
Sérgio Luís Gomes Antunes, A. B. R. Ferreira, E.J. Shannon, Felipe G. Sandoval, Thiago Gomes de Toledo-Pinto, Patrícia Sammarco Rosa, Lucia Elena Alvarado-Arnez, Diana L. Williams, Leonardo Ribeiro Batista-Silva, Marcelo Ribeiro-Alves, Flávio Alves Lara, Alejandra N. Martinez, Luciana Silva Rodrigues, Bruno Jorge de Andrade Silva, Euzenir Nunes Sarno, Milton Ozório Moraes, Maria Cristina Vidal Pessolani, Roberta Olmo Pinheiro, Robertha Mariana Rodrigues Lemes
Publikováno v:
Journal of Infectious Diseases. 214:311-320
Cytosolic detection of nucleic acids elicits a type I interferon (IFN) response and plays a critical role in host defense against intracellular pathogens. Herein, a global gene expression profile of Mycobacterium leprae-infected primary human Schwann
Publikováno v:
Leprosy Review. 79:311-314
Summary Objective The immune-mediated events that precipitate erythema nodosum leprosum (ENL) are not well understood. One component may be the complexing of antibody with antigens released from infected macrophages, the activation of complement and
Publikováno v:
Immunopharmacology and Immunotoxicology. 30:447-457
Thalidomide is used to treat erythema nodosum leprosum (ENL). The events that precipitate this inflammatory reaction, which may occur in multibacillary leprosy patients, and the mechanism by which thalidomide arrest ENL, are not known. Thalidomide's
Publikováno v:
Translational Research. 150:275-280
An early rationale for using thalidomide to treat erythema nodosum leprosum had been based on some reports that it suppresses tumor necrosis factor-alpha (TNF-alpha). However, in vivo and in vitro studies have yielded variable results, having shown t
Autor:
Michael T. Kearney, Edward J. Shannon, Abolghasem Baghian, Anna Israyelyan, Felipe G. Sandoval
Publikováno v:
Immunopharmacology and immunotoxicology. 34(3)
Thalidomide (Thal) can suppress the growth of established, as well as explanted tumors in mice. We wanted to determine if it could suppress the ability of tumor cells to assemble and establish a primary tumor at the injection site. Using the mouse 4T
Publikováno v:
Leprosy review. 79(3)
The immune-mediated events that precipitate erythema nodosum leprosum (ENL) are not well understood. One component may be the complexing of antibody with antigens released from infected macrophages, the activation of complement and the subsequent loc
Autor:
Naoko Robbins, Stephen Keas, Diana L. Williams, Thomas P. Gillis, David M. Scollard, Felipe G. Sandoval, Cheryl Lewis
Publikováno v:
Clinical Infectious Diseases. 58:72-73
Molecular drug susceptibility testing was performed on 39 US patients with leprosy. Of these, 2 had dapsone-resistant Mycobacterium leprae and 1 of these patients also had rifampin-resistant M. leprae. Even though antileprosy drug resistance occurs i
Autor:
Felipe G. Sandoval, Edward J. Shannon
Publikováno v:
International immunopharmacology. 2(8)
Thalidomide is a drug that can enhance mitogen- and antigen-stimulated cells' ability to synthesize IL-2. To assess if thalidomide could concomitantly enhance the synthesis of IFN-gamma and incorporation of [H3]-thymidine, peripheral blood mononuclea
Autor:
Felipe G. Sandoval, Thiago Gomes de Toledo-Pinto, Anna Beatriz Robottom-Ferreira, Euzenir Nunes Sarno, Tiana Rosa Brito, Sérgio Luís Gomes Antunes, Patrícia Sammarco Rosa, E.J. Shannon, Diana L. Williams, Milton Ozório Moraes, Marcelo Ribeiro-Alves, Márcia Rodrigues Jardim, Maria Cristina Vidal Pessolani, Luana Tatiana Albuquerque Guerreiro
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64748 (2013)
PLoS ONE
PLoS ONE
Herein, we performed microarray experiments in Schwann cells infected with live M. leprae and identified novel differentially expressed genes (DEG) in M. leprae infected cells. Also, we selected candidate genes associated or implicated with leprosy i