Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Felipe Freitas-Castro"'
Autor:
Francisca S Borges, José C Quilles, Lucas B Lorenzon, Caroline R Espada, Felipe Freitas-Castro, Tânia P A Defina, Fabíola B Holetz, Angela K Cruz
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0292152 (2024)
In the protozoan parasite Leishmania, most genes encoding for ribosomal proteins (RPs) are present as two or more copies in the genome. However, their untranslated regions (UTRs) are predominantly divergent and might be associated with a distinct reg
Externí odkaz:
https://doaj.org/article/cdd62abe89a644a783d583c35fe89490
Autor:
Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Adriene Y. Ishimoto, Warrison A. C. de Andrade, Leticia de Almeida, Felipe Freitas-Castro, Sabrina S. Batah, Sergio C. Oliveira, Mônica T. Pastorello, Alexandre T. Fabro, Dario S. Zamboni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, de Sá et al. show that Gasdermin-D is transiently activated in Leishmania-infected macrophages and promotes NLRP3 inflammasome activation, but not cell death. Gasdermin-D is cleaved into a noncanonical fragment, indicating that Leishmania subv
Externí odkaz:
https://doaj.org/article/1a83c20a305e4205a732e3e7fc4d594d
Autor:
Camila Gachet-Castro, Felipe Freitas-Castro, Raul Alexander Gonzáles-Córdova, Carol Kobori da Fonseca, Marcelo Damário Gomes, Hellen Cristina Ishikawa-Ankerhold, Munira Muhammad Abdel Baqui
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the causative agent of Chagas Disease, lives intracellularly within host cells. During infection, parasite-associated modifications occur to the host cell metabolism an
Externí odkaz:
https://doaj.org/article/2792006712bc4640a8169ed8dd498448
Autor:
Gustavo F C Fagundes, Felipe Freitas-Castro, Lucas S Santana, Ana Caroline F Afonso, Janaina Petenuci, Mariana F A Funari, Augusto G Guimaraes, Felipe L Ledesma, Maria Adelaide A Pereira, Carolina R Victor, Marcela S M Ferrari, Fernando M A Coelho, Victor Srougi, Fabio Y Tanno, Jose L Chambo, Ana Claudia Latronico, Berenice B Mendonca, Maria Candida B V Fragoso, Ana O Hoff, Madson Q Almeida
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
ContextLimited information is available concerning the genetic spectrum of pheochromocytoma and paraganglioma (PPGL) patients in South America. Germline SDHB large deletions are very rare worldwide, but most of the individuals harboring the SDHB exon
Autor:
Rohit Sharma, Monica Cristina Terrão, Felipe Freitas Castro, Reinhard Breitling, Vitor Faça, Eduardo Brandt Oliveira, Angela Kaysel Cruz
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203369 (2018)
The N-end rule pathway leads to regulated proteolysis as an adaptive response to external stress and is ubiquitous from bacteria to mammals. In this study, we investigated a gene coding for a putative core enzyme of this post-translational regulatory
Externí odkaz:
https://doaj.org/article/b9d4b1dc7cf14066803a363e7f34f907
Autor:
Cibele Cardoso, Josane de Freitas Sousa, Felipe Freitas-Castro, Graziela de Moura Aguiar, Natália Volgarine Scaraboto, Sarah C. Simões, Anelisa Ramão, Jessica Rodrigues Plaça, Wilson A. Silva
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
BACKGROUND: Expression dysregulation of HOX homeobox genes has been observed in several cancers, including head and neck squamous cell carcinoma (HNSC). Although characterization of HOX gene roles in HNSC development has been reported, there is still
Autor:
Carol Kobori da Fonseca, Marcelo D. Gomes, Raul Alexander Gonzáles-Córdova, Camila Gachet-Castro, Munira Muhammad Abdel Baqui, Felipe Freitas-Castro, Hellen Ishikawa-Ankerhold
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the causative agent of Chagas Disease, lives intracellularly within host cells. During infection, parasite-associated modifications occur to the host cell metabolism an
Autor:
Thiago M. Cunha, Kiyoshi F. Fukutani, Edecio Cunha-Neto, João Santana da Silva, Eduardo Antônio Donadi, Carlos Alessandro Fuzo, Fabrício C. Dias, Maria Cláudia Silva, Felipe Freitas-Castro, Tiago Medina
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. During the chronic phase of disease, while most infected people do not present symptoms, characterizing the asymptomatic form, some patients develop the cardiac form or chronic cha
Autor:
Angela K. Cruz, Felipe Freitas-Castro
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
In the last 30 years, significant advances in genetic manipulation tools along with complete genome and transcriptome sequencing have advanced our understanding of the biology of Leishmania parasites and their interplay with the sand fly and mammalia
Autor:
Tania Paula Aquino Defina, Patrícia de Cássia Ruy, Leandro R. Dias, Felipe Freitas-Castro, Angela K. Cruz, Natália Melquie Monteiro-Teles, Elton J R Vasconcelos, Rubens Daniel Miserani Magalhães, Peter J. Myler
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Leishmaniasis is a worldwide public health problem caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the most important species responsible for tegumentary leishmaniases in Brazil. An understanding of the molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed16d7617e55bf523ad3d88a3c2442cf