Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Felipe Flores-Santibañez"'
Autor:
Felipe Flores-Santibañez, Sofie Rennen, Dominique Fernández, Clint De Nolf, Evelien Van De Velde, Sandra Gaete González, Camila Fuentes, Carolina Moreno, Diego Figueroa, Álvaro Lladser, Takao Iwawaki, María Rosa Bono, Sophie Janssens, Fabiola Osorio
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In cancer, activation of the IRE1/XBP1s axis of the unfolded protein response (UPR) promotes immunosuppression and tumor growth, by acting in cancer cells and tumor infiltrating immune cells. However, the role of IRE1/XBP1s in dendritic cells (DCs) i
Externí odkaz:
https://doaj.org/article/989ab48b82084085b311233598ad7ae2
Autor:
Francisca Gutiérrez-Ballesteros, Jonathan Morales-Reyes, Dominique Fernández, Antonia Geisse, Amada Arcaya, Felipe Flores-Santibañez, María Rosa Bono, Fabiola Osorio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The initiation of adaptive immunity relies on the performance of dendritic cells (DCs), which are specialized leukocytes with professional antigen presenting capabilities. As such, the molecular mechanisms safeguarding DC homeostasis are matter of in
Externí odkaz:
https://doaj.org/article/0d37b543cdfb4ebb9291ef188c4cc50a
Autor:
Gabriela Tejon, Nicolás Valdivieso, Felipe Flores-Santibañez, Verónica Barra-Valdebenito, Víctor Martínez, Mario Rosemblatt, Daniela Sauma, María Rosa Bono
Publikováno v:
Molecular Biology Reports. 49:4193-4204
BackgroundSeveral studies have demonstrated the contribution of innate immune cells, including macrophages, in promoting systemic lupus erythematosus (SLE). Macrophages, one of the most abundant cell populations in the peritoneal cavity, are consider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2cb51f3ed35e49c057e95255bd26e5
https://doi.org/10.1007/s11033-022-07252-0
https://doi.org/10.1007/s11033-022-07252-0
Autor:
Felipe Flores-Santibañez, Sofie Rennen, Dominique Fernandez, Clint De Nolf, Sandra Gaete, Camila Fuentes, Carolina Moreno, Diego Figueroa, Álvaro Lladser, Takao Iwawaki, María Rosa Bono, Sophie Janssens, Fabiola Osorio
The IRE1/XBPls axis of the unfolded protein response (UPR) plays divergent roles in dendritic cell (DC) biology in steady state versus tumor contexts. Whereas tumor associated DCs show dysfunctional IRE1/XBP1s activation that curtails their function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c92915ba299af3ba832c01f5d6e1fd
https://doi.org/10.1101/2022.07.20.500838
https://doi.org/10.1101/2022.07.20.500838
Autor:
Yessia Hidalgo, Sarah Núñez, Maria Jose Fuenzalida, Felipe Flores-Santibáñez, Pablo J. Sáez, Jessica Dorner, Ana-Maria Lennon-Dumenil, Victor Martínez, Emmanuel Zorn, Mario Rosemblatt, Daniela Sauma, Maria Rosa Bono
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the activation of autoreactive T and B cells, autoantibody production, and immune complex deposition in various organs. Previous evidence showed abnormal accumulation of B c
Externí odkaz:
https://doaj.org/article/0f41c6a3db1d40fbab671f264b1a1c4a
Autor:
Felipe Flores-Santibáñez, Bárbara Cuadra, Dominique Fernández, Mariana V. Rosemblatt, Sarah Núñez, Pablo Cruz, Felipe Gálvez-Cancino, J. César Cárdenas, Alvaro Lladser, Mario Rosemblatt, María Rosa Bono, Daniela Sauma
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Memory CD8+ T cells are ideal candidates for cancer immunotherapy because they can mediate long-term protection against tumors. However, the therapeutic potential of different in vitro-generated CD8+ T cell effector subsets to persist and become memo
Externí odkaz:
https://doaj.org/article/b297c67dc13f4823995ba0780a1fbd43
Autor:
Dominique Fernández, Felipe Flores-Santibáñez, Jocelyn Neira, Francisco Osorio-Barrios, Gabriela Tejón, Sarah Nuñez, Yessia Hidalgo, Maria Jose Fuenzalida, Daniel Meza, Gonzalo Ureta, Alvaro Lladser, Rodrigo Pacheco, Claudio Acuña-Castillo, Victoria Guixé, Francisco J Quintana, Maria Rosa Bono, Mario Rosemblatt, Daniela Sauma
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157889 (2016)
T helper type 17 (Th17) lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, are present in intestinal lamina propria and have been described as important players driving intestinal inflammation. Recent
Externí odkaz:
https://doaj.org/article/1e734191b82a4327915313039879c8e1