Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Felipe Dias Leal"'
1
Akademický článek
Hologram QSAR Models of a Series of 6-Arylquinazolin-4-Amine Inhibitors of a New Alzheimer’s Disease Target: Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase-1A Enzyme
Autor: Felipe Dias Leal, Camilo Henrique da Silva Lima, Ricardo Bicca de Alencastro, Helena Carla Castro, Carlos Rangel Rodrigues, Magaly Girão Albuquerque
Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 3, Pp 5235-5253 (2015)
Dual specificity tyrosine-phosphorylation-regulated kinase-1A (DYRK1A) is an enzyme directly involved in Alzheimer’s disease, since its increased expression leads to β-amyloidosis, Tau protein aggregation, and subsequent formation of neurofibrilla
Externí odkaz: https://doaj.org/article/9d4258c0d20441949cccfc81b45d9b63
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2
Akademický článek
New perspectives and recommendations for anticoagulant therapy post orthopedic surgery
Autor: Marcelo Kropf, Cleidson Alves Bergami, Felipe Dias Leal, Claudia Oliveira Dias Passos, Zilda de Santana Gonsalves, Isabela Laudares Marques, Isabela Azevedo Mota, Marcele Lima Monte Gonçalves
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 47, Iss 4, Pp 655-663 (2011)
Anticoagulant therapy is essential for the prevention of risks associated with the formation of thrombus in patients after surgery, especially in orthopedics. Recently, new oral anticoagulants were introduced in the therapeutic arsenal. This fact is
Externí odkaz: https://doaj.org/article/364e498df4d34c3eaea0a0f6fb4c4648
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3
Otimização de uma formulação magistral de espessante alimentício utilizando planejamento estatístico de misturas
Autor: Loraynne Vargas Machado Teixeira, Adriana Silveira Pereira de Melo, Aline Guerra Manssour Fraga, Elisabete Pereira dos Santos, Paula Fernandes de Aguiar, Felipe Dias Leal, Ana Lúcia Vazquez Villa
Publikováno v: Research, Society and Development; Vol. 11 No. 16; e28111637528
Research, Society and Development; Vol. 11 Núm. 16; e28111637528
Research, Society and Development; v. 11 n. 16; e28111637528
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
A disfagia caracteriza-se por um distúrbio da deglutição ou qualquer dificuldade do trânsito do bolo alimentar da boca até o estômago de origem congênita ou adquirida, podendo estar associada a complicações. Agentes espessantes são utilizad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cac89c4c2b75ec72cd9d3f92aedf3a5
https://rsdjournal.org/index.php/rsd/article/view/37528
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4
Detection of new exemestane metabolites by liquid chromatography interfaced to electrospray-tandem mass spectrometry
Autor: Francisco Radler de Aquino Neto, Felipe Dias Leal, Francesco Botrè, Gustavo de Albuquerque Cavalcanti, Monica Costa Padilha, Bruno C. Garrido, Monica Mazzarino, Xavier de la Torre
Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 127:248-254
Exemestane is an irreversible aromatase inhibitor used for anticancer therapy. Unfortunately, this drug is also misused in sports to avoid some adverse effects caused by steroids administration. For this reason exemestane has been included in World A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e827c154406b89630cd4c40b85158d1d
https://doi.org/10.1016/j.jsbmb.2011.08.014
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5
Hologram QSAR models of a series of 6-arylquinazolin-4-amine inhibitors of a new Alzheimer's disease target: dual specificity tyrosine-phosphorylation-regulated kinase-1A enzyme
Autor: Ricardo Bicca de Alencastro, Felipe Dias Leal, Magaly Girão Albuquerque, Helena Carla Castro, Camilo Henrique da Silva Lima, Carlos Rangel Rodrigues
Publikováno v: International Journal of Molecular Sciences
Volume 16
Issue 3
Pages 5235-5253
International Journal of Molecular Sciences, Vol 16, Iss 3, Pp 5235-5253 (2015)
Dual specificity tyrosine-phosphorylation-regulated kinase-1A (DYRK1A) is an enzyme directly involved in Alzheimer’s disease, since its increased expression leads to β-amyloidosis, Tau protein aggregation, and subsequent formation of neurofibrilla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f7726e2d159b51ca8750e41ab9fd2
https://pubmed.ncbi.nlm.nih.gov/25756379
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6
Specificity and selectivity improvement in doping analysis using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry
Autor: Samantha Soares Barbosa, Ademário I. da Silva Júnior, Francisco Radler de Aquino Neto, Monica Costa Padilha, Raphael S. F. Silva, Henrique Marcelo G. Pereira, Felipe Dias Leal
Publikováno v: Química Nova v.35 n.5 2012
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Vol 35, Iss 5, Pp 982-987 (2012)
ResearcherID
Química Nova, Volume: 35, Issue: 5, Pages: 982-987, Published: 2012
Comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry was used for the identification of forty doping agents. The improvement in the specificity was remarkable, allowing the resolution of analytes that could n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1dea95a3f283bd75a41fd16605cb05
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000500022
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7
New perspectives and recommendations for anticoagulant therapy post orthopedic surgery
Autor: Cleidson Alves Bergami, Isabela Laudares Marques, Claudia Oliveira Dias Passos, Felipe Dias Leal, Isabela Azevedo Mota, Zilda de Santana Gonsalves, Marcelo Kropf, Marcele Lima Monte Gonçalves
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Volume: 47, Issue: 4, Pages: 655-663, Published: DEC 2011
Brazilian Journal of Pharmaceutical Sciences, Vol 47, Iss 4, Pp 655-663 (2011)
Brazilian Journal of Pharmaceutical Sciences; Vol. 47 No. 4 (2011); 655-663
Brazilian Journal of Pharmaceutical Sciences; Vol. 47 Núm. 4 (2011); 655-663
Brazilian Journal of Pharmaceutical Sciences; v. 47 n. 4 (2011); 655-663
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Anticoagulant therapy is essential for the prevention of risks associated with the formation of thrombus in patients after surgery, especially in orthopedics. Recently, new oral anticoagulants were introduced in the therapeutic arsenal. This fact is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d933f42ead57193be718baef3338c716
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400002&lng=en&tlng=en
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8
Detection of new urinary exemestane metabolites by gas chromatography coupled to mass spectrometry
Autor: Bruno C. Garrido, Monica Costa Padilha, Xavier de la Torre, Gustavo de Albuquerque Cavalcanti, Felipe Dias Leal, Francisco Radler de Aquino Neto
Publikováno v: Steroids. 76(10-11)
Exemestane is an aromatase enzyme complex inhibitor. Its metabolism in humans is not fully described and there is only one known metabolite: 17β-hydroxyexemestane. In this work, excretion studies were performed with four volunteers aiming at the det
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ed5def47e722b230826a172714c859
https://pubmed.ncbi.nlm.nih.gov/21530565
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