Výsledky vyhledávání - "Felipe Beccaria Casagrande"

Akademický článek

Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site

Autor: Ilyas Chachoua, Ilias Tzelepis, Hao Dai, Jia Pei Lim, Anna Lewandowska-Ronnegren, Felipe Beccaria Casagrande, Shuangyang Wu, Johanna Vestlund, Carolina Diettrich Mallet de Lima, Deeksha Bhartiya, Barbara A. Scholz, Mirco Martino, Rashid Mehmood, Anita Göndör

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Gene-gating of a MYC oncogenic super-enhancer (OSE) increases its expression in colon cancer cells in a poorly understood process. Here the authors show that MYC gating requires a CTCF binding site (CTCFBS) within the OSE that directs the stepwise tr

Externí odkaz: https://doaj.org/article/893a77cc51f74de0b36357c417ac2c2c

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Akademický článek

Insulin Modulates Inflammatory Cytokine Release in Acute Stages and Augments Expression of Adhesion Molecules and Leukocytes in Lungs on Chronic Stages of Paracoccidioidomycosis

Autor: Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Emanuella Sarmento Alho de Sousa, João Pedro Tôrres Guimarães, Lavínia Maria Dal’Mas Romera, Fernando Henrique Galvão Tessaro, Sandro Rogério de Almeida, Stephen Fernandes de Paula Rodrigues, Joilson O. Martins

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Type 1 diabetesmellitus (T1D) is caused by partial destruction of the insulin-producing beta cells in the pancreas and is a major issue for public health care worldwide. Reduced or impaired immunological responses, which render patients more suscepti

Externí odkaz: https://doaj.org/article/793f78e2948646a2bed9dd41ba2719f8

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Akademický článek

Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs

Autor: Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Fernanda Peixoto Barbosa Nunes, Lavínia Maria Dal’Mas Romera, Suelen Silvana dos Santos, Fernando Henrique Galvão Tessaro, Paula Regina Knox de Souza, Sandro Rogério Almeida, Joilson Oliveira Martins

Publikováno v: Journal of Diabetes Research, Vol 2018 (2018)

Paracoccidioidomycosis, a key issue for Brazilian health service, can be aggravated in patients with impaired immunological responses, such as diabetic patients. We evaluated the role of insulin in inflammatory parameters in diabetic and nondiabetic

Externí odkaz: https://doaj.org/article/7e04e41548c84045b4c01bba3234d9cb

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Dissertation/ Thesis

Efeito da insulina em micose sistêmica causada por Paracoccidioides brasiliensis em animais diabéticos e sadios

Autor: Felipe Beccaria Casagrande

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

A paracoccidioidomicose é uma enfermidade sistêmica causada principalmente pelo fungo Paracoccidioides brasiliensis. Recentemente, observou-se que a capacidade fagocítica dos macrófagos alveolares (MA) em animais diabéticos está diminuída em c

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-19102015-100624/

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Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

Publikováno v: Cardiovascular Research.

AimsRecent studies have revealed a close connection between cellular metabolism and the chronic inflammatory process of atherosclerosis. While the link between systemic metabolism and atherosclerosis is well established, the implications of altered m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc4e5f7d56c6c5f4fc76b3882b6a3d5e
https://doi.org/10.1093/cvr/cvad038

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Insulin Modulates Inflammatory Cytokine Release in Acute Stages and Augments Expression of Adhesion Molecules and Leukocytes in Lungs on Chronic Stages of Paracoccidioidomycosis

Autor: Sabrina de Souza Ferreira, João Pedro Tôrres Guimarães, Joilson O. Martins, Lavínia Maria Dal'Mas Romera, Sandro Rogério de Almeida, Fernando Henrique Galvão Tessaro, Stephen F. Rodrigues, Felipe Beccaria Casagrande, Emanuella Sarmento Alho de Sousa

Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Type 1 diabetes mellitus (T1D) is caused by partial destruction of the insulin-producing beta cells in the pancreas and is a major issue for public health care worldwide. Reduced or impaired immunological responses, which render patients more suscept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94a33369bc30677270479de06f6d005
https://doi.org/10.3389/fimmu.2020.583385

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Insulin modulates cell migration and cytokines secretion during pulmonary infection caused by Paracoccidioides brasiliensis in diabetic and non-diabetic mice

Autor: Felipe Beccaria Casagrande

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

Diabetes mellitus (DM) compreende um conjunto de doenças metabólicas de grande importância e incidência mundial. Nele, o DM do tipo 1 é caracterizado pela destruição de células pancreáticas produtoras de insulina, e dentre seus sintomas, a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0809b13976b1e07387d2385fe610433

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Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice

Autor: Felipe Beccaria Casagrande, Maristela Tsujita, Momtchilo Russo, Eliane Gomes, Maria Aparecida Oliveira, Wothan Tavares de Lima, Fernanda Peixoto Barbosa Nunes, Sabrina de Souza Ferreira, Joilson O. Martins

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

Introduction: Reports have shown that the onset of diabetes mellitus (DM) in patients previously diagnosed with asthma decreases asthmatic symptoms, whereas insulin aggravates asthma. The present study evaluated the modulatory effect of insulin on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b494b4a15368ae1bce0caff56d8419d8

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Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs

Autor: Sabrina de Souza Ferreira, Suelen Silvana dos Santos, Lavínia Maria Dal'Mas Romera, Sandro Rogério de Almeida, Fernando Henrique Galvão Tessaro, Fernanda Peixoto Barbosa Nunes, Paula Regina de Souza, Joilson O. Martins, Felipe Beccaria Casagrande

Publikováno v: Journal of Diabetes Research
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Diabetes Research, Vol 2018 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d664e772eab9c60ddb9920cc6163f4

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Insulin modulates cytokine release, collagen and mucus secretion in lung remodeling of allergic diabetic mice

Autor: Felipe Beccaria Casagrande, Joilson O. Martins, Sabrina de Souza Ferreira, Fernanda Peixoto Barbosa Nunes

Introduction The role of insulin in lung remodeling in a model of asthma in healthy and diabetic mice was evaluated. Material and methods Diabetic male BALB/c mice (alloxan, 50 mg/kg, intravenous) and controls were sensitized by subcutaneous (s.c.) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dfcb0619706fb60360972f5b6b3d6e

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