Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Felipe Alcudia"'
Publikováno v:
Tetrahedron. 60:871-875
The Diels–Alder reaction of enantiomerically pure (E)-γ-keto-α,β-unsaturated p-tolylsulphoxides 3 with cyclopentadiene give four easily separable diastereomers. The effect of several Lewis acids on the reaction was studied, finding a high endo s
Autor:
Eugenia Blanco, Fernando Iglesias-Guerra, José M. Vega-Pérez, Felipe Alcudia, José I. Candela
Publikováno v:
Chirality. 14:199-203
Chlorambucilamide derivatives involving chiral glycosyl glycerols derived from D-glucosamine were synthesized in good yield by coupling the chlorambucil moiety to the amino group of ω-amino-(ω-1)-hydroxyalkyl 2-acylamino-4,6-O-benzylidene-2-deoxy-
Publikováno v:
The Journal of Organic Chemistry. 67:345-356
Two modular and highly convergent approaches for the synthesis of both isomers of a large number of optically pure C(2)-symmetric bis-sulfoxides have been developed, and their scope and limitations have been assessed. The first one uses as intermedia
C 2 -Symmetric Bis-Sulfoxide: Highly Diastereoselective 1,4-Addition to Stabilised Michael Acceptors
Publikováno v:
Tetrahedron. 56:3749-3753
The reaction of (S,S)-bis-p-tolylsulfinylmethane with highly stabilised Michael acceptors was studied in detail. The stereochemical outcome of the reaction was shown to be under thermodynamic control. While an equimolar mixture of Michael adducts was
Autor:
Aranzazu Roca, Inmaculada Fernández, Abdelhak Benabra, José L. Espartero, Noureddine Khiar, Ana Alcudia, Felipe Alcudia
Publikováno v:
Tetrahedron Letters. 40:2029-2032
Various chiral secondary alcohols have been used to study the dependence of the stereochemical outcome of sulfinate and phosphinate ester synthesis on the nature of the base used to catalyse the reaction. From this study it has been shown that the ac
Publikováno v:
Carbohydrate Research. 308:57-62
Cyclophosphamides derived from alkyl 2-amino-4,6- O -benzylidene-2-deoxy- β - d -allopyranosides have been synthesized with good yield by treatment of the corresponding 2-amino-2-deoxy- d -allose derivatives with bis(2-chloroethyl)phosphoramide dich
Publikováno v:
Tetrahedron: Asymmetry. 7:3353-3356
The stereochemical outcome of the reaction of chiral secondary alcohols with a phosphinyl chloride was found to be highly dependent on the achiral base used. Thus, the reaction of the readily available sugar derived carbinols, 1 and 2 , with methylph
Autor:
Margarita Vega, Felipe Alcudia, José I. Candela, Fernando Iglesias-Guerra, José M. Vega-Pérez
Publikováno v:
Journal of Mass Spectrometry. 31:493-499
The electron impact ionization mass spectra of new alkyl (and phenyl) 4,6-benzylidene-2-amino-N-alkyl- and N,N-dialkyl-2-deoxy-D-hexopyranosides and benzyl (and phenyl) 4,6-O-benzylidene-2,3-di-O-alkyl-D- hexopyranosides were examined. Three general
Publikováno v:
Tetrahedron Letters. 35:5719-5722
Diacetone- D -glucose (DAG) reacts with t -BuSOCl in the presence of NEt 3 and Py to give (−)-( S )- and (+)-( R )- tert -butanesulfinate respectively, in high diastereomeric excess. These sulfinates were transformed into various enantiomerically p
Publikováno v:
Tetrahedron: Asymmetry. 5:709-716
Homochiral D - and L -hexose precursors have been prepared in good overall yield from ( R )-methyl- p -tolylsulfoxide as the sole asymmetric inductor. The process involves sequential condensation of the sulfoxide with ethyl 2-furancarboxylate, stereo