Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Felipe, Batalini"'
Autor:
Christos Miliotis, Yuling Ma, Xanthi-Lida Katopodi, Dimitra Karagkouni, Eleni Kanata, Kaia Mattioli, Nikolas Kalavros, Yered H. Pita-Juárez, Felipe Batalini, Varune R. Ramnarine, Shivani Nanda, Frank J. Slack, Ioannis S. Vlachos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The landscape of non-coding mutations in cancer progression and immune evasion is largely unexplored. Here, we identify transcrptome-wide somatic and germline 3′ untranslated region (3′-UTR) variants from 375 gastric cancer patients from
Externí odkaz:
https://doaj.org/article/7e900114ce37476b816c721095f77f00
Autor:
Shizhong Ke, Fabin Dang, Lin Wang, Jia-Yun Chen, Mandar T. Naik, Wenxue Li, Abhishek Thavamani, Nami Kim, Nandita M. Naik, Huaxiu Sui, Wei Tang, Chenxi Qiu, Kazuhiro Koikawa, Felipe Batalini, Emily Stern Gatof, Daniela Arango Isaza, Jaymin M. Patel, Xiaodong Wang, John G. Clohessy, Yujing J. Heng, Galit Lahav, Yansheng Liu, Nathanael S. Gray, Xiao Zhen Zhou, Wenyi Wei, Gerburg M. Wulf, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/CCDH1) prevents cell-cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-act
Externí odkaz:
https://doaj.org/article/0b6bab263e5b452fb61f77b6a5e52d6a
Autor:
Riccardo Panella, Cody A. Cotton, Valerie A. Maymi, Sachem Best, Kelsey E. Berry, Samuel Lee, Felipe Batalini, Ioannis S. Vlachos, John G. Clohessy, Sakari Kauppinen, Pier Paolo Pandolfi
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1470 (2023)
microRNA-22 (miR-22) is an oncogenic miRNA whose up-regulation promotes epithelial-mesenchymal transition (EMT), tumor invasion, and metastasis in hormone-responsive breast cancer. Here we show that miR-22 plays a key role in triple negative breast c
Externí odkaz:
https://doaj.org/article/2a0cc842d22f401da62df9ad1d52e98f
Publikováno v:
BMJ case reports. 15(4)
A woman in her 50s previously treated for early-stage breast cancer, parotid mucoepidermoid carcinoma and Caroli's disease was diagnosed with stage IV pancreatic ductal adenocarcinoma (PDAC) metastatic to the liver and was found to harbour a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b3a28236e4a49048377ed63eb779d49
https://pubmed.ncbi.nlm.nih.gov/35487638
https://pubmed.ncbi.nlm.nih.gov/35487638
Publikováno v:
Future Science OA, Vol 8, Iss 4 (2022)
Cancer is associated with significant morbimortality globally. Advances in screening, diagnosis, management and survivorship were substantial in the last decades, however, challenges in providing personalized and data-oriented care remain. Artificial
Externí odkaz:
https://doaj.org/article/fcc7a83b023b4febae8696244c6f16b7
Autor:
Felipe Batalini, Ellie G. Peacock, Lindsey Stobie, Alison Robertson, Judy Garber, Jeffrey N. Weitzel, Nadine M. Tung
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract The introduction of next-generation sequencing has resulted in testing multiple genes simultaneously to identify inherited pathogenic variants (PVs) in cancer susceptibility genes. PVs with low minor allele frequencies (MAFs) (
Externí odkaz:
https://doaj.org/article/ec32db004ab8481dbdebc4950356163f
Autor:
Felipe Batalini, Doga C. Gulhan, Xanthi Lida Katopodi, Nikolas Kalavros, Antuan Tran, Dimitra Karagkouni, Emily Stern-Gatof, Stuart Schnitt, Judy E. Garber, Gerburg M. Wulf, Peter J. Park, Ioannis Vlachos, Nadine Tung
Publikováno v:
Cancer Research. 83:P5-12
Background Breast cancers in women with a germline BRCA1/2 mutation (gBRCAm) have homologous recombination deficiency (HRD) and are sensitive to therapies causing double-strand DNA breaks. In TBCRC 031 (INFORM), both neoadjuvant cisplatin and doxorub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::225c6bbf0d4d72b8011aead8cfde79c6
https://doi.org/10.1158/1538-7445.sabcs22-p5-12-03
https://doi.org/10.1158/1538-7445.sabcs22-p5-12-03
Publikováno v:
Respiratory Medicine Case Reports, Vol 27, Iss , Pp - (2019)
Immune checkpoint inhibitors are known to cause a variety of immune-related adverse events, including pneumonitis. When symptomatic, treatment typically consists of temporary or permanent cessation of the checkpoint inhibitor and several weeks of cor
Externí odkaz:
https://doaj.org/article/27da89c6fba448568ad2a280f1be5024
Autor:
Gerburg M. Wulf, Peter J. Park, Hans P. Eikesdal, Helen Won, David B. Solit, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Per E. Lønning, Stian Knappskog, Erica L. Mayer, Eric P. Winer, Nadine M. Tung, Nabihah Tayob, Niya Xiong, Madeline Polak, Antuan Tran, Victor Mao, Doga C. Gulhan, Felipe Batalini
Supplementary Figure from Mutational Signature 3 Detected from Clinical Panel Sequencing is Associated with Responses to Olaparib in Breast and Ovarian Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76099960cff7a30f9165cf9999813e69
https://doi.org/10.1158/1078-0432.22488711
https://doi.org/10.1158/1078-0432.22488711
Autor:
Gerburg M. Wulf, Peter J. Park, Hans P. Eikesdal, Helen Won, David B. Solit, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Per E. Lønning, Stian Knappskog, Erica L. Mayer, Eric P. Winer, Nadine M. Tung, Nabihah Tayob, Niya Xiong, Madeline Polak, Antuan Tran, Victor Mao, Doga C. Gulhan, Felipe Batalini
Purpose:The identification of patients with homologous recombination deficiency (HRD) beyond BRCA1/2 mutations is an urgent task, as they may benefit from PARP inhibitors. We have previously developed a method to detect mutational signature 3 (Sig3),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03e9c8c371af9cc37633a91a713e1fa
https://doi.org/10.1158/1078-0432.c.6532794
https://doi.org/10.1158/1078-0432.c.6532794